The DOI matches its Crossref record; 97 of the 97 references it cites were found in a registry or an index.
The inner world of overactive monitoring: neural markers of interoception in obsessive–compulsive disorder
Open accessAbstract
Background: Obsessive–compulsive disorder (OCD) patients typically overmonitor their own behavior, as shown by symptoms of excessive doubt and checking. Although this is well established for the patients’ relationship with external stimuli in the environment, no study has explored their monitoring of internal body signals, a process known to be affected in anxiety-related syndromes. Here, we explored this issue through a cardiac interoception task that measures sensing of heartbeats. Our aim was to explore key behavioral and electrophysiological aspects of internal-cue monitoring in OCD, while examining their potential distinctiveness in this condition. Method: We administered a heartbeat detection (HBD) task (with related interoceptive confidence and awareness measures) to three matched groups (OCD patients, panic disorder patients, healthy controls) and recorded ongoing modulations of two task-relevant electrophysiological markers: the heart evoked potential (HEP) and the motor potential (MP). Results: Behaviorally, OCD patients outperformed controls and panic patients in the HBD task. Moreover, they exhibited greater amplitude modulation of both the HEP and the MP during cardiac interoception. However, they evinced poorer confidence and awareness of their interoceptive skills. Conclusions: Convergent behavioral and electrophysiological data showed that overactive monitoring in OCD extends to the sensing of internal bodily signals. Moreover, this pattern discriminated OCD from panic patients, suggesting a condition-distinctive alteration. Our results highlight the potential of exploring interoceptive processes in the OCD spectrum to better characterize the population's cognitive profile. Finally, these findings may lay new bridges between somatic theories of emotion and cognitive models of OCD.
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“Interoceptive abnormalities are noted in psychoses (Brosey and Woodward, 2017), obsessive-compulsive disorders (Yoris et al., 2017) and eating disorders (Jenkinson et al., 2018).”
From Physiological feelings (2019) · cites this paper as Yoris et al., 2017
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“While the majority of clinical conditions are associated with reduced interoceptive accuracy, interoceptive accuracy has been found to be increased in anxiety and panic disorder (for reviews, see Domschke et al., 2010; Paulus and Stein, 2010) and in OCD (Yoris et al., 2017).”
From Atypical interoception as a common risk factor for psychopathology: A review (2021) · cites this paper as Yoris et al., 2017
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“consistent with research findings that individuals with OCD over-monitor their internal bodily signals, such as heart beats [65].”
From Habit as a therapeutic component in psychological treatment for obsessive-compulsive disorder: A randomised controlled feasibility study. (2026) · cites this paper as [65]
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Citations
Cites
The Hospital Anxiety and Depression Scale
Zigmond, A. S., & Snaith, R. P. (1983) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1983.tb09716.x · Cited by 47,139
Nonparametric permutation tests for functional neuroimaging: A primer with examples
Nichols, T. E., & Holmes, A. P. (2002) · Human Brain Mapping · doi:10.1002/hbm.1058 · Cited by 6,256
How do you feel? Interoception: The sense of the physiological condition of the body
Craig, A. D. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn894 · Cited by 6,006
Randomization, Bootstrap and Monte Carlo Methods in Biology
Manly, B. F. J. (2018) · Chapman & Hall/CRC eBooks · doi:10.1201/9781315273075 · Cited by 4,209
Neural systems supporting interoceptive awareness
Critchley, H. D., Wiens, S., Rotshtein, P., Öhman, A., & Dolan, R. J. (2004) · Nature Neuroscience · doi:10.1038/nn1176 · Cited by 3,406 · cited 7×
“2016), fMRI studies and meta-analyses (Critchley et al. 2004; Pollatos et al. 2007; Schulz et al. 2016), and brain stimulation studies (Pollatos et al.”
BackgroundMethodInfluentialThe Obsessive-Compulsive Inventory: Development and validation of a short version.
Foa, E. B., Huppert, J. D., Leiberg, S., Langner, R., Kichic, R., Hajcak, G., & Salkovskis, P. M. (2002) · Psychological Assessment · doi:10.1037/1040-3590.14.4.485 · Cited by 2,959
Self-citationThe epidemiology of obsessive-compulsive disorder in the National Comorbidity Survey Replication
Ruscio, A. M., Stein, D. J., Chiu, W. T., & Kessler, R. C. (2010) · Molecular Psychiatry · doi:10.1038/mp.2008.94 · Cited by 2,771
Interoception: the sense of the physiological condition of the body
(Bud) Craig, A. (2003) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(03)00090-4 · Cited by 2,556
Obsessional-compulsive problems: A cognitive-behavioural analysis
Salkovskis, P. M. (1985) · Behaviour Research and Therapy · doi:10.1016/0005-7967(85)90105-6 · Cited by 1,842
Knowing your own heart: Distinguishing interoceptive accuracy from interoceptive awareness
Garfinkel, S. N., Seth, A. K., Barrett, A. B., Suzuki, K., & Critchley, H. D. (2015) · Biological Psychology · doi:10.1016/j.biopsycho.2014.11.004 · Cited by 1,624
Research works printed but not linked: 3
- Spielberger, 1970, Manual for the Stait-Trait Anxiety Inventory
- First, 2002, Structured Clinical Interview for DSM-IV Axis I Disorders, Research Version, Patient Edition (SCID-I/P)
- 1994, DSM-IV: Diagnostic and Statistical Manual
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Dynamic Regulation of Interoceptive Processing in Relaxation and AnxietyPreprint
Zhang, J., Zhang, Y., Hua, J., Li, N., Northoff, G., & Luo, Y. (2025) · Research Square · doi:10.21203/rs.3.rs-7435608/v1
Raviv, L., Tarrasch, R., & Dar, R. (2026) · Research Square · doi:10.21203/rs.3.rs-9556022/v1
I sync, therefore I am: brain–body synchrony in typical and disordered consciousness
Young, A., Ericson, M., & Schooler, J. W. (2026) · Neuroscience of Consciousness · doi:10.1093/nc/niag028
“OCD patients outperform controls on heartbeat detection tasks and show greater early-to-mid HEP amplitude during both interoceptive and exteroceptive monitoring, despite poorer confidence and metacognitive awareness of their interoceptive performance ( Yoris et al. 2017).”
Wang, J., Li, E., An, X., & Ming, D. (2026) · Psychological Medicine · doi:10.1017/s003329172610453x · Cited by 2
“…(notably the right frontal cortex), central areas, and parietal lobes (Cambi et al., 2024; Flasbeck et al., 2020; Herrera et al., 2025; Judah et al., 2018; Koreki et al., 2024; Lutz et al., 2019; Müller et al., 2015; Pang et al., 2019; Terhaar et al., 2012; Yoris et al., 2017; Zhou et al., 2022).”
Can the Heartbeat-Evoked Potential (HEP) be Separated from Cardiac Artefact (CA) Using Beamforming?Preprint
Virjee, R.-I., Kandasamy, R., Garfinkel, S. N., Yogarajah, M., Vladimir Litvak, A., & Carmichael, D. W. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.07.11.737958
Wilson, L. A., Scarfo, J., Sambol, S., Coceski, M., & Rehm, I. C. (2026) · Journal of Psychopathology and Behavioral Assessment · doi:10.1007/s10862-026-10319-y
“Alternative interoceptive profiles may have emerged had a sam - ple of participants with clinically verified OCD diagnoses been compared to healthy controls (e.g., Eng et al., 2020, 2022 ) or related clinical groups (e.g., anxiety disorders; Yoris et al., 2017 ).”
Hartmann, H., Proposito, A., Riva, F., & Lamm, C. (2026) · Psychophysiology · doi:10.1111/psyp.70391
“Moreover, an imbalance in difficulty between the interoceptive and exteroceptive conditions has been observed in other studies using similar intero-ceptive tasks (Salamone et al. 2020; Yoris et al. 2017).”
Zhang, G., Han, H., Cheng, J., Luo, Q., Stern, E. R., & Wang, Z. (2026) · Biological Psychiatry · doi:10.1016/j.biopsych.2026.10.014
Metadata
- Authors
- Yoris, A., García, A. M., Traiber, L., Santamaría-García, H., Martorell, M., Alifano, F., Kichic, R., Moser, J. S., Cetkovich, M., Manes, F., Ibáñez, A., & Sedeño, L.
- Affiliations
- Consejo Nacional de Investigaciones Científicas y Técnicas (AR)
- Instituto de Neurología Cognitiva (AR)
- Favaloro University (AR)
- Michigan State University (US)
- Corresponding author
- Sedeño, L.
- Venue
- Psychological Medicine
- Publisher
- Cambridge University Press (CUP)
- Published
- 2017-04-04
- Volume
- 47
- Issue
- 11
- Pages
- 1957-1970
- ISSN
- 0033-2917 (ISSN-L)
- 1469-8978
- OpenAlex
- W2604761667
- Cited by
- 124
- References
- 97
- Citations by year
- 2026: 13 · 2025: 8 · 2024: 9 · 2023: 17 · 2022: 8 · 2021: 12 · 2020: 14 · 2019: 27 · 2018: 10 · 2017: 6
- FWCI
- 19.28
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Psychological Medicine (publishedVersion)
- PubMed (publishedVersion)
- Americanae (AECID Library) (submittedVersion, cc-by-nc-nd)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (submittedVersion, cc-by-nc-nd)
- CONICET Digital (CONICET) (submittedVersion, cc-by-nc-sa)
- Funders
- Fundación INECO (15150012)
- Consejo Nacional de Investigaciones Científicas y Técnicas (1130920, 15150012)
- Comisión Nacional de Investigación Científica y Tecnológica (FONDAP-15150012, 1140114, 15150012, 1130920)
- Fondo para la Investigación Científica y Tecnológica (2012-0412, 2012‐1309, PICT 2012)
- Fondo de Financiamiento de Centros de Investigación en Áreas Prioritarias (15150012)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- obsessive-compulsive disorder, interoception, heartbeat detection, motor potential, interoceptive awareness, panic disorder
- MeSH terms
- Adult, Evoked Potentials, Female, Heart Rate, Humans, Male, Middle Aged, Obsessive-Compulsive Disorder, Panic Disorder, Evoked Potentials, Motor, Young Adult, Interoception
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