The DOI matches its Crossref record.
Mechanisms of cooperativity and allosteric regulation in proteins
Abstract
AUosteric proteins control and coordinate chemical events in the living cell. When Monod conceived that idea he said that he had discovered the second secret of life. The first was the structure of DNA. The theory as published by Monod et al.(1963) was concerned chiefly with cooperativity and feedback inhibition of enzymes, such as the inhibition of threonine deaminase, the first enzyme in the pathway of the synthesis of isoleucine, by isoleucine, and its activation by valine. Two years later the theory was formalized by Monod et al.(1965).
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Dendron-Mediated Self-Assembly, Disassembly, and Self-Organization of Complex Systems
Rosen, B. M., Wilson, C. J., Wilson, D. A., Peterca, M., Imam, M. R., & Percec, V. (2009) · Chemical Reviews · doi:10.1021/cr900157q · Cited by 1,204
Structural Symmetry and Protein Function
Goodsell, D. S., & Olson, A. J. (2000) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.biophys.29.1.105 · Cited by 950
Cooperativity in Noncovalent Interactions
Mahadevi, A. S., & Sastry, G. N. (2016) · Chemical Reviews · doi:10.1021/cr500344e · Cited by 933
Hunter, C. A., & Anderson, H. L. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200902490 · Cited by 802
Synthetische molekulare Motoren und mechanische Maschinen
Kay, E. R., Leigh, D. A., & Zerbetto, F. (2007) · Angewandte Chemie · doi:10.1002/ange.200504313 · Cited by 624
Metadata
- Authors
- Perutz, M. F.
- Venue
- Quarterly Reviews of Biophysics
- Publisher
- Cambridge University Press (CUP)
- Published
- 1989-05
- Volume
- 22
- Issue
- 2
- Pages
- 139-237
- ISSN
- 0033-5835 (ISSN-L)
- 1469-8994
- OpenAlex
- W4230158786
- Cited by
- 645
- References
- 0
- FWCI
- 2.12
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Mechanisms of cooperativity and allosteric regulation in proteins. https://app.cochat.ai/papers/10.1017/s0033583500003826
- The paper
- Perutz, M. F. (1989). Mechanisms of cooperativity and allosteric regulation in proteins. Quarterly Reviews of Biophysics. https://doi.org/10.1017/s0033583500003826
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
