The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Cognitive Behaviour Therapy for Health Anxiety: A Systematic Review and Meta-Analysis
Open accessAbstract
Background: Health anxiety (HA), or hypochondriasis, is a psychological problem characterized by a preoccupation with the belief that one is physically unwell. A 2007 Cochrane review (Thomson and Page, 2007) found cognitive behavioural therapy (CBT) to be an effective intervention for individuals with HA. Similar findings were reported in a recent meta-analysis (Olatunji et al., 2014), which did not employ a systematic search strategy. The current review aimed to investigate the efficacy of CBT for HA, and to update the existing reviews. Method: A systematic search was conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidance, including randomized controlled trials that compared CBT with a control condition for people with HA. Five hundred and sixty-seven studies were found in the original search, of which 14 were included in the meta-analysis. Results: Meta-analysis was conducted on 21 comparisons and a large effect size for CBT compared with a control condition was found at post therapy d = 1.01 (95% confidence interval 0.77–1.25), as well as at 6- and 12-month follow-up. Conclusions: This systematic review and meta-analysis provides support for the hypothesis that CBT is an effective intervention for HA when compared with a variety of control conditions, e.g. treatment-as-usual, waiting list, medication, and other psychological therapies.
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Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
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Cochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series
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BARSKY, A. J., Orav, E. J., & Bates, D. W. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.8.903 · Cited by 912
Warwick, H. M. C., & Salkovskis, P. M. (1990) · Behaviour Research and Therapy · doi:10.1016/0005-7967(90)90023-c · Cited by 587 · cited 2×
“Warwick and Salkovskis (1990) have suggested that HA is best thought of as a continuum, with full clinical diagnosis at the upper end.”
BackgroundSelf-citationSalkovskis, P. M., & Warwick, H. M. C. (1986) · Behaviour Research and Therapy · doi:10.1016/0005-7967(86)90041-0 · Cited by 475 · cited 1×
“…of HA (Warwick & Salkovskis, 1990) has resulted in the development of a focused treatment (Salkovskis, Warwick, & Deale, 2003) which has been tested in single cases (Salkovskis & Warwick, 1986), case series (Warwick & Marks, 1988), and randomised controlled trials (Clark et al., 1998).”
BackgroundSelf-citationA systematic review of the epidemiology of somatisation disorder and hypochondriasis
Creed, F., & Barsky, A. (2004) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(03)00622-6 · Cited by 421
Cognitive Behavior Therapy for Hypochondriasis
BARSKY, A. J., & Ahern, D. K. (2004) · JAMA · doi:10.1001/jama.291.12.1464 · Cited by 322
Two psychological treatments for hypochondriasis: A randomised controlled trial
Clark, D. M., Salkovskis, P. M., Hackmann, A., Wells, A., Fennell, M., Ludgate, J., Ahmad, S., Richards, H. C., & Gelder, M. (1998) · British Journal of Psychiatry · doi:10.1192/bjp.173.3.218 · Cited by 270
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Research works printed but not linked: 1
- 2013, Diagnostic and Statistical Manual of Mental Disorders
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Items 101–118 of 118
Sassen, B. (2023) · Springer eBooks · doi:10.1007/978-3-031-11255-3_7
Zortea, T. C., Salkovskis, P. M., & Craig, C. (2023) · FPOP Bulletin Psychology of Older People · doi:10.53841/bpsfpop.2023.1.163.57
Self-citationArneaud, G. J., Buchanan, T., Gautier, C., & Nadarzynski, T. (2023) · Journal of Psychosexual Health · doi:10.1177/26318318231221923
A clinician’s quick guide to evidence-based approaches: health anxiety
Mahoney, A., Dobinson, K. A., Millard, M., & Newby, J. M. (2024) · Clinical Psychologist · doi:10.1080/13284207.2024.2402333
Adaptation and validation of the Health Anxiety Inventory (short version) for medical settings
Colenutt, J., & Daniels, J. (2025) · The Cognitive Behaviour Therapist · doi:10.1017/s1754470x2400045x · Cited by 1
“…criteria of illness anxiety and somatic symptom disorder (American Psychiatric Association, 2013) and more anxiety based conceptual models that are empirically well supported and evidence based (Cooper et al ., 2017), a review of the utility of current measurements of health anxiety is warranted.”
Nayebzadeh, M., & Emadi, S. E. (2025) · International journal of new findings in health and educational sciences (IJHES). · doi:10.63053/ijhes.114
Sušac, V., & Beljan, I. (2025) · Zdravstveni glasnik · doi:10.47960/2303-8616.2025.1.11.132
Bleichhardt, G. M. (2025) · PiD - Psychotherapie im Dialog · doi:10.1055/a-2420-4264
Davies, J., Salkovskis, P., Laidlaw, K., & Beck, J. S. (2025) · Cambridge University Press eBooks · doi:10.1017/9781009090940.019
Self-citationCrawford, M. J., King, J. D., McQuaid, A., Bassett, P., Leeson, V. C., Tella, O., Di Simplicio, M., Tyrer, P., Tyrer, H., Watt, R. G., et al. (2024) · Figshare · doi:10.6084/m9.figshare.24954503
Ming, J., Chen, H., Li, Y., Wu, X., Zhang, F., & Nie, D. (2025) · BMC Women s Health · doi:10.1186/s12905-025-04129-9
“…counseling [10]), tiered psychological therapies such as cognitive-behavioral therapy for high-risk groups (HPV16/18, newly diagnosed patients) [42, 43], and culturally tailored education initiatives such as de-stigmatization campaigns (e.g., “HPV ≠ Moral Defect”) paired with grassroots health…”
Cocks, F., Davis, C., Peters, C., Nicola, R. D., & Daniels, J. (2026) · Behavioural and Cognitive Psychotherapy · doi:10.1017/s1352465825101252
“Treatment based on this approach has been found to be effective across medical conditions (Cooper et al ., 2017; Daniels et al ., 2020; Petricone-Westwood et al ., 2019; Tyrer et al ., 2021).”
Landeros, C., & Luo, X. I. (2026) · American Journal of Health Promotion · doi:10.1177/08901171261426773
YAPAY ZEKA TEMELLI KURULUŞLARDA DÖNÜŞÜMSEL LIDERLIĞIN ETKISI: BİR META-ANALIZ
Yazıcı, A. M. (2026) · Doğuş Üniversitesi Dergisi · doi:10.31671/doujournal.1706530
Lai, L., Liu, Y., Axelsson, E., Tyrer, P., Li, Y., Lu, Y., Shi, C., & Ren, Z. (2026) · The British Journal of Psychiatry · doi:10.1192/bjp.2026.10647
Therapie von Zwangsspektrumsstörungen
(2024) · Elsevier eBooks · doi:10.1016/b978-3-437-22541-3.00017-8
Fear of psychosis in an OCD analogue sample: Prevalence and associated factors
Pennell, A., Bishop, O. C., Fawcett, J. M., & Fawcett, E. J. (2026) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2026.102139
Özgür, A. E., Kasım, İ., & Uğraş, E. (2026) · Eurasian Journal of Family Medicine · doi:10.33880/ejfm.2026150309
Metadata
- Authors
- Cooper, K., Gregory, J. D., Walker, I., Lambe, S., & Salkovskis, P. M.
- Affiliations
- University of Bath (GB)
- Venue
- Behavioural and Cognitive Psychotherapy
- Publisher
- Cambridge University Press (CUP)
- Published
- 2017-02-23
- Volume
- 45
- Issue
- 2
- Pages
- 110-123
- ISSN
- 1352-4658 (ISSN-L)
- 1469-1833
- OpenAlex
- W2541165905
- Cited by
- 118
- References
- 31
- Citations by year
- 2026: 9 · 2025: 15 · 2024: 16 · 2023: 10 · 2022: 14 · 2021: 13 · 2020: 15 · 2019: 16 · 2018: 7 · 2017: 1
- FWCI
- 1.68
- Type
- journal article
- Language
- en
- Open access
- Licence
- Locations
- Behavioural and Cognitive Psychotherapy (publishedVersion)
- PubMed (publishedVersion)
- ORCA Online Research @Cardiff (Cardiff University) (acceptedVersion)
- ORCA Online Research @Cardiff (Cardiff University) (submittedVersion)
- The University of Bath Online Publications Store (The University of Bath) (submittedVersion)
- Pure (University of Bath) (submittedVersion, other-oa)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Assessments
- Keywords
- cognitive behavioral therapy, health anxiety, treatment efficacy, psychological intervention, control conditions, follow-up outcomes
- MeSH terms
- Anxiety, Anxiety Disorders, Humans, Hypochondriasis, Psychotherapy, Cognitive Behavioral Therapy
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