The DOI matches its Crossref record; the references it cites are not checked yet.
Neurocognitive consequences of HIV in southern India:A preliminary study of clade C virus
Abstract
The neurocognitive impact of the clade C viral strain of human immunodeficiency virus (HIV) has not been determined. The purpose of this study was to examine neurocognitive function in southern India among individuals with the clade C virus with advanced HIV. A battery of cognitive tasks sensitive to the effects of HIV on brain function was translated and administered in Tamil and Telegu, two widely spoken languages in southern India. A sample of 30 treatment-naïve HIV-positive individuals with a median CD4 cell count of 97, and 30 age and education matched healthy controls obtained from the same region of India, were included in the study. Results revealed significant differences on most cognitive tests, with lower performances obtained by the HIV-positive individuals. These results suggest that cognitive difficulties are present among individuals with the clade C virus in India, with as many as 56% of the patients with advanced HIV meeting the criterion for impairment in two cognitive domains. Additional study is needed to determine if clade C HIV infection is more or less prone to cause neurocognitive deficit than the clade B virus. Furthermore, the impact of antiretroviral therapy on neurocognitive dysfunction in clade C virual infection needs to be determined.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In an Indian study, among patients with advanced HIV, 56% met the criterion for impairment in two cognitive domains.
“In an Indian study, among patients with advanced HIV, 56% were found to meet the criterion for impairment in two cognitive domains.[5]”
From Management of psychiatric disorders with HIV and dermatological disorders (2022) · cites this paper as [5]
Citations
The citation lists haven’t been fetched yet
References 24 · Cited by 73
Research works printed but not linked: 1
- Das Gupta, J. , Kumar, K.G. , Rao, S.L. , Wilkie, F.L. , Waldrop-Valverde, D. , Subbakrishna, D.K. , Desai, A. , Ravi, V. , Rao, B.S. , Satish, K.S. , Kumar, M. , & Satishchandra, P. (2005).Cognitive deficits in neurologically asymptomatic HIV-seropositiveadults: A study from South India.Poster presented at the HIV Infection and the Central NervousSystem: Developed and Resource Limited Settings conference, Frascati,Italy.
Metadata
- Authors
- YEPTHOMI, T., PAUL, R., VALLABHANENI, S., KUMARASAMY, N., TATE, D. F., SOLOMON, S., & FLANIGAN, T.
- Affiliations
- YR Gaitonde Centre for AIDS Research and Education (IN)
- Brown University (US)
- Venue
- Journal of the International Neuropsychological Society
- Publisher
- Cambridge University Press (CUP)
- Published
- 2006-05
- Volume
- 12
- Issue
- 3
- Pages
- 424-430
- ISSN
- 1355-6177 (ISSN-L)
- 1469-7661
- OpenAlex
- W1980018132
- Cited by
- 73
- References
- 24
- Citations by year
- 2024: 1 · 2022: 1 · 2021: 2 · 2020: 5 · 2019: 6 · 2017: 4 · 2016: 4 · 2015: 8 · 2014: 4 · 2013: 6 · 2012: 4
- FWCI
- 1.62
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the International Neuropsychological Society (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (K23MH065857, K23MH073416, K23MH65857)
- National Institute of Allergy and Infectious Diseases (P30-AI 42853, P30AI042853)
- Topics
- Life Sciences › Immunology and Microbiology › Virology › HIV Research and Treatment
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS drug development and treatment
- Health Sciences › Medicine › Infectious Diseases › Infectious Diseases and Tuberculosis
- Keywords
- HIV-associated neurocognitive disorders, advanced HIV disease, neurocognitive impairment, cognitive function, Tamil language, South India, antiretroviral therapy, treatment-naive HIV
- MeSH terms
- Adult, Brain, Cognition Disorders, Female, Humans, India, Male, Neuropsychological Tests, Severity of Illness Index, HIV-1, HIV Infections, CD4 Antigens
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review