The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Galectins: structure, function and therapeutic potential
Open accessAbstract
Galectins are a family of animal lectins that bind β-galactosides. Outside the cell, galectins bind to cell-surface and extracellular matrix glycans and thereby affect a variety of cellular processes. However, galectins are also detectable in the cytosol and nucleus, and may influence cellular functions such as intracellular signalling pathways through protein–protein interactions with other cytoplasmic and nuclear proteins. Current research indicates that galectins play important roles in diverse physiological and pathological processes, including immune and inflammatory responses, tumour development and progression, neural degeneration, atherosclerosis, diabetes, and wound repair. Some of these have been discovered or confirmed by using genetically engineered mice deficient in a particular galectin. Thus, galectins may be a therapeutic target or employed as therapeutic agents for inflammatory diseases, cancers and several other diseases.
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Cites
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Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation
Demetriou, M., Granovsky, M., Quaggin, S., & Dennis, J. W. (2001) · Nature · doi:10.1038/35055582 · Cited by 901
Regulation of Cytokine Receptors by Golgi N-Glycan Processing and Endocytosis
Partridge, E. A., Le Roy, C., Di Guglielmo, G. M., Pawling, J., Cheung, P., Granovsky, M., Nabi, I. R., Wrana, J. L., & Dennis, J. W. (2004) · Science · doi:10.1126/science.1102109 · Cited by 735
Toscano, M. A., Bianco, G. A., Ilarregui, J. M., Croci, D. O., Correale, J., Hernandez, J. D., Zwirner, N. W., Poirier, F., Riley, E. M., Baum, L. G., et al. (2007) · Nature Immunology · doi:10.1038/ni1482 · Cited by 653
Self-citationCritical role of galectin-3 in phagocytosis by macrophages
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Self-citationRole of galectin-3 in diabetic nephropathy
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Cited by
Yu, L., Ruifrok, W. P. T., Meissner, M., Bos, E. M., van Goor, H., Sanjabi, B., van der Harst, P., Pitt, B., Goldstein, I. J., Koerts, J. A., et al. (2013) · Circulation: Heart Failure · doi:10.1161/circheartfailure.112.971168 · Cited by 435
Sato, S., St‐Pierre, C., Bhaumik, P., & Nieminen, J. (2009) · Immunological Reviews · doi:10.1111/j.1600-065x.2009.00790.x · Cited by 299
Macrophages in spinal cord injury: Phenotypic and functional change from exposure to myelin debris
Wang, X., Cao, K., Sun, X., Chen, Y., Duan, Z., Sun, L., Guo, L., Bai, P., Sun, D., Fan, J., et al. (2015) · Glia · doi:10.1002/glia.22774 · Cited by 288
Lalancette-Hébert, M., Swarup, V., Beaulieu, J. M., Bohacek, I., Abdelhamid, E., Weng, Y. C., Sato, S., & Kriz, J. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.1498-12.2012 · Cited by 251
Potapenko, I. O., Haakensen, V. D., Lüders, T., Helland, Å., Bukholm, I., Sørlie, T., Kristensen, V. N., Lingjærde, O. C., & Børresen-Dale, A.-L. (2010) · Molecular Oncology · doi:10.1016/j.molonc.2009.12.001 · Cited by 158
Metadata
- Authors
- Yang, R.-Y., Rabinovich, G. A., & Liu, F.-T.
- Venue
- Expert Reviews in Molecular Medicine
- Publisher
- Cambridge University Press (CUP)
- Published
- 2008-06
- Volume
- 10
- Pages
- e17-e17
- ISSN
- 1462-3994 (ISSN-L)
- OpenAlex
- W2138790009
- Cited by
- 862
- References
- 7
- FWCI
- 13.93
- Type
- journal article
- Language
- en
- Open access
- bronze
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
