Theoretical Design and Analysis of Multivolume Digital Assays with Wide Dynamic Range Validated Experimentally with Microfluidic Digital PCR
Kreutz, Jason E., Munson, Todd, Huynh, Toan, Shen, Feng, Du, Wenbin, Ismagilov, Rustem F.·2011·Analytical Chemistry
Cited by (148)
Items 101–148 of 148
- Designing and interpretation of digital assays: Concentration of target in the sample and in the source of samplePawel R. Debski, Piotr Garstecki · 2016 · Biomolecular Detection and Quantification
- Size-tunable droplet microfluidic system using an on-chip microfluidic peristaltic pumpTuo Ma, Yousu Wang, Shixin Sun, Tingrui Pan, Baoqing Li, Jiaru Chu · 2021 · Sensors and Actuators A Physical
- Rapid and semiquantitative detection of Staphylococcus epidermidis in humor samples by microfluidic platformXinlian Zhang, Xiaoxu Li, Qi Liu, Shaorui Ke, Yinghong Ji, Sixiu Liu, Guodong Sui · 2018 · Sensors and Actuators B Chemical
- Fabrication and packaging of a mass-producible capillary-assembled microchip for simple and multiplexed bioassayTerence G. Henares, Akihiro Shirai, Kenji Sueyoshi, Tatsuro Endo, Hideaki Hisamoto · 2015 · Sensors and Actuators B Chemical
- Application of Droplet Digital PCR Technology in Muscular Dystrophies ResearchIoana Maria Lambrescu, Alexandra Popa, Emilia Manole, Laura Cristina Ceafalan, Gisela F. Gaina · 2022 · International Journal of Molecular Sciences
- Calibration-free assays on standard real-time PCR devicesPawel R. Debski, Kamil Gewartowski, Seweryn Bajer, Piotr Garstecki · 2017 · Scientific Reports
- Microfluidic One-Pot Digital Droplet FISH Using LNA/DNA Molecular Beacons for Bacteria Detection and Absolute QuantificationYu‐Ting Kao, Silvia Calabrese, Nadine Borst, Michael Lehnert, Yu-Kai Lai, Franziska Schlenker, Peter Juelg, Roland Zengerle, Piotr Garstecki, Felix von Stetten · 2022 · Biosensors
- A size reduction method for rapid digital PCR using thin-film chip and vacuum pouch microfluidic systemCheng-Je Lee, Yu‐Hsiang Hsu · 2021 · Microfluidics and Nanofluidics
- Ferrodrop Dose-Optimized Digital Quantification of Biomolecules in Low-Volume SamplesSoroush Kahkeshani, Janay Elise Kong, Qingshan Wei, Derek K. Tseng, Omai B. Garner, Aydogan Özcan, Dino Di Carlo · 2018 · Analytical Chemistry
- Detachable and reassemble sandwiching device with high dynamic range for multivolume droplet digital polymerase chain reactionsChunyang Wei, Chengzhuang Yu, Jiyu Meng, Junwei Li, Qinghua Li, Shanshan Li · 2023 · Sensors and Actuators B Chemical
- SlipChip Device for Digital Nucleic Acid AmplificationFeng Shen · 2017 · Methods in molecular biology
- Rapid and ultrasensitive digital PCR (dPCR) profiling of EGFRvIII in tumor cells and tissuesDeeksha Saxena, Saad Sheikh, Gary D. Kao, Zev A. Binder, Michelle Alonso‐Basanta, Donald M. O’Rourke, MacLean P. Nasrallah, Jay F. Dorsey · 2019 · Neuro-Oncology Advances
- General methods for quantitative interpretation of results of digital variable-volume assaysToan Huynh, Samantha A. Byrnes, Tim C. Chang, Bernhard H. Weigl, Kevin Paul Nichols · 2019 · The Analyst
- Role of periodic inner dripping on compound jets in a capillary deviceZhaomiao Liu, Ju Wang, Yan Pang, Qiang Zhou, Mengqi Li · 2019 · International Journal of Multiphase Flow
- Modular RCA-CRISPR/Cas12a amplification on a multi-volume SlipChip for ultrafast, single-copy quantification of circRNA and miRNA in ovarian cancerLingxi Tian, Yan Gao, Lu Yang, Xu Feng, Zirui Feng, Lihan Zi, Zaian Deng, Jun Yang · 2025 · Lab on a Chip
- Investigation of co-flow step emulsification (CFSE) microfluidic device and its applications in digital polymerase chain reaction (ddPCR)Chunyang Wei, Wei Lv, Yanjing Ding, Chen Wang, Chengduo Sun, X.M. Feng, Tianqi Zhang, Junwei Li, Qinghua Li, Shanshan Li · 2024 · Journal of Colloid and Interface Science
- Detection of microRNAs Using Chip-Based QuantStudio 3D Digital PCRCristina Borzi, Linda Calzolari, Davide Conte, Gabriella Sozzi, Orazio Fortunato · 2017 · Methods in molecular biology
- Multiplex Immunoassays Utilizing Differential Affinity Using Aptamers Generated by MARASJi-Ching Lai, Horng-Er Horng, Chin‐Yih Hong · 2017 · Scientific Reports
- New Precision Engineering Methods for Low‐Cost Mass Production of Functional Giant Magnetic Glass‐Coated Particles as Immune BiomarkersSuk‐Heung Song, Sujeong Lim, Hye-Yeon Choi, Ju-Ho Kim, Yong‐Gyun Jung, Wook Park · 2020 · Advanced Engineering Materials
- Flow-LAMP: Label-Free Digital LAMP Using Scatter-Based Flow Cytometry on Vortex-Generated Polydisperse Gel BeadsYuchong Zheng, Wanjun Yao, Zerui Wu, Liqun He, Weidong Zheng, Zida Li · 2025 · Analytical Chemistry
- Current and emerging molecular diagnostic approaches in the detection of human parasitesDario Pistone, Giulia Bevivino, Maria Greta Dipaola, Claudio Bandi, Fabrizio Lombardo · 2026 · Parasitology Research
- Advances in absolute quantitative PCR and biomedical applicationsShiChao LI, Feng Xu, XiaYu XU, Lei Cao, Ting Wen, Tianjian Lu, Bin GAO, Yinghui Li · 2016 · Scientia Sinica Vitae
- A Multi‐Volume Microfluidic Device for Automated and Wide Dynamic Range Digital LAMP ApplicationsKaiyue Chen, Nan Rong, Chanqiong Zhang, Jian Xu, Hao Hua He, Wenying Liu, Yinjia Xu, Yanzhao Wu, Qi Ouyang, Yunlong Zhou et al. · 2024 · Advanced Materials Technologies
- Microfluidic Tools for DNA AnalysisYi Zhang, Xingyu Jiang · 2013 · Springer eBooks
- Should genetic testing go digital?Michael A. VanInsberghe, Kevin A. Heyries, Carl L. Hansen · 2012 · Expert Review of Molecular Diagnostics
- An Automated Multi-Sample Digital LAMP Platform for Quantitative Detection of SDC2 Methylation in Colorectal CancerHao Hua He, Yanzhao Wu, Lai Wei, Lin Zhou, Zhirui Liu, Nan Rong, Chunxiong Luo, Chanqiong Zhang, Wei Yang · 2025 · Analytical Chemistry
- StratoLAMP-2: A Microfluidics-Free, Deep-Learning Platform for Multiplex Digital Molecular DiagnosticsJiazhao Chen, Jingyi Ding, Rui Deng, Yi Wang, Zida Li · 2025 · Analytical Chemistry
- Microfluidic digital focus assays for the quantification of infectious influenza virusSiddharth Raghu Srimathi, Maxinne A. Ignacio, Maria Flaquer Rife, Sheldon Tai, Donald Kirby Milton, Margaret A. Scull, Don L. DeVoe · 2025 · Lab on a Chip
- Fabrication of planar monolayer microreactor array for visual statistical analysis and droplet-based digital quantitative analysis in situNing Zhang, Chao Yue, Junping Liu, Xiaobo Zhan, Zhi Cheng, Chao Li, Yaohua Du, Feng Tian · 2022 · Analytical and Bioanalytical Chemistry
- Surface Acoustic Wave Nebulization as a Mass Spectrometry Ionization Source, Characterization and ApplicationYue Huang · 2014 · ResearchWorks at the University of Washington (University of Washington)
- Lossless and Contamination-Free Digital PCRPeiyu Liao, Mengcheng Jiang, Zitian Chen, Fangli Zhang, Yue Ming Sun, Jun Hui Nie, Meijie Du, Jianbin Wang, Peng Fei, Yanyi Huang · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Optimizing the Single-Molecule Counting Process of Solid-State NanoporesMartin Charron · 2020 · uO Research (University of Ottawa)
- A digital nonenzymatic nucleic acid amplification assay for ultrasensitive detection of cell-free microRNA in human serumTao Yu, Aditi Dey Poonam, Amy A. Halbing, Shengwei Zhang, Yingmiao Liu, Zheng Li, William Marx, Andrew B. Nixon, Qingshan Wei · 2025 · Sensors & Diagnostics
- SlipChip: from principle to applicationsYang Luo, Weijie Yuan, Sujin Jung, Feng Shen · 2026 · Lab on a Chip
- Systematic characterization and mechanistic insights into ultrasonically actuated sharp-tip capillary droplet generationQi Zhang, Li Ran, Gang Li · 2026 · Lab on a Chip
- Partitioning and subsampling statistics in compartment-based quantification methodsManuel Loskyll, Daniel Podbiel, Andreas Erwin Guber, Jochen H. O. Hoffmann · 2023 · PLoS ONE
- Materials-driven innovations in digital nucleic acid amplification technologies: Transforming molecular diagnosticsJiazhao Chen, Jingyi Ding, Kai Wu, Zida Li · 2025 · Chemical Engineering Journal
- Mechanistic Studies of Reactions at the Single-Molecule Level using Microfluidics with Applications in Molecular DiagnosticsBing Sun · 2014 · CaltechTHESIS (California Institute of Technology)
- Design, Analysis, and Translation of 3D Hydrodynamic Tweezer MicroeddiesValerie H. Lieu · 2012 · ResearchWorks at the University of Washington (University of Washington)
- Absolute Nucleic Acid Quantification System and AnalysisBofan Song, Qi Song, W. Jin, Qingchang Tian, Ying Mu · 2015 · International Conference on Industrial Technology and Management Science (ITMS)
- Microdroplet Array for Nucleic Acid Amplification StrategiesYingnan Sun · 2019 · Springer eBooks
- Absolute quantification of particle number concentration using a digital single particle counting systemLi Zhang, Yujun Yang, Jun-Yi Xiong, Zhen Wu, Zhixiong Xie, Dai‐Wen Pang, Zhiling Zhang · 2019 · Microchimica Acta
- Test Article for automation purposesNing Zhang, Chao Li, Xuechen Dou, Yaohua Du, Feng Tian · 2022 · Critical Reviews in Analytical Chemistry
- Droplet-based Microfluidic Platform for Quantitative MicrobiologyCyprien Guermonprez · 2016
- A digital droplet microarray for measuring tolerance to antibioticsRena Fukuda, Nadia Nikulin, Shenghao Tan, Tobias Dörr, Nate Cira · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- A compact centrifugal multi-volume digital PCR disk (MV-dPCR disk) with integrated pneumatic stabilizationYu-Kai Lai, Marvin Heyer, Silvia Calabrese, Tobias Hutzenlaub, Nils Paust, Jacob Friedrich Hess · 2026 · Lab on a Chip
- Digital bioassays through the lens of partitioning strategiesUlysse Le Bas, Guillaume Gines · 2026 · Chemical Communications
- SANDWiCH: An Oil-Free High-Throughput Microwell-Array Platform for Digital Loop-Mediated Isothermal AmplificationJeonghwan Oh, Dong Hyun Han, Jong-Ho Park, Juhyun Lee, Kyung Tae Noh, Je-Kyun Park · 2026 · Analytical Chemistry