The DOI matches its Crossref record.
Synthesis-Modification Integration: One-Step Fabrication of Boronic Acid Functionalized Carbon Dots for Fluorescent Blood Sugar Sensing
Abstract
In this paper, we have presented a novel strategy to fabricate fluorescent boronic acid modified carbon dots (C-dots) for nonenzymatic blood glucose sensing applications. The functionalized C-dots are obtained by one-step hydrothermal carbonization, using phenylboronic acid as the sole precursor. Compared with conventional two-step fabrication of nanoparticle-based sensors, the present "synthesis-modification integration" strategy is simpler and more efficient. The added glucose selectively leads to the assembly and fluorescence quenching of the C-dots. Such fluorescence responses can be used for well quantifying glucose in the range of 9-900 μM, which is 10-250 times more sensitive than that of previous boronic acid based fluorescent nanosensing systems. Due to "inert" surface, the C-dots can well resist the interferences from various biomolecules and exhibit excellent selectivity. The proposed sensing system has been successfully used for the assay of glucose in human serum. Due to simplicity and effectivity, it exhibits great promise as a practical platform for blood glucose sensing.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Glowing Graphene Quantum Dots and Carbon Dots: Properties, Syntheses, and Biological Applications
Zheng, X. T., Ananthanarayanan, A., Luo, K. Q., & Chen, P. (2015) · Small · doi:10.1002/smll.201402648 · Cited by 2,190
Nanocarbons for Biology and Medicine: Sensing, Imaging, and Drug Delivery
Panwar, N., Soehartono, A. M., Chan, K. K., Zeng, S., Xu, G., Qu, J., Coquet, P., Yong, K.-T., & Chen, X. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.9b00099 · Cited by 555
Iravani, S., & Varma, R. S. (2020) · Environmental Chemistry Letters · doi:10.1007/s10311-020-00984-0 · Cited by 532
Li, L., & Dong, T. (2018) · Journal of Materials Chemistry C · doi:10.1039/c7tc05878k · Cited by 452
Pan, D., Jiao, J., Li, Z., Guo, Y., Feng, C., Liu, Y., Wang, L., & Wu, M. (2015) · ACS Sustainable Chemistry & Engineering · doi:10.1021/acssuschemeng.5b00771 · Cited by 304
Metadata
- Authors
- Shen, P., & Xia, Y.
- Venue
- Analytical Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2014-05-22
- Volume
- 86
- Issue
- 11
- Pages
- 5323-5329
- ISSN
- 0003-2700 (ISSN-L)
- 1520-6882
- OpenAlex
- W2042246864
- Cited by
- 596
- References
- 0
- FWCI
- 24.27
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Synthesis-Modification Integration: One-Step Fabrication of Boronic Acid Functionalized Carbon Dots for Fluorescent Blood Sugar Sensing. https://app.cochat.ai/papers/10.1021/ac5001338
- The paper
- Shen, P., & Xia, Y. (2014). Synthesis-Modification Integration: One-Step Fabrication of Boronic Acid Functionalized Carbon Dots for Fluorescent Blood Sugar Sensing. Analytical Chemistry. https://doi.org/10.1021/ac5001338
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
