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Cited by 304

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Fabricating Large Arrays of Microwells with Arbitrary Dimensions and Filling Them Using Discontinuous Dewetting

Jackman, Rebecca J., Duffy, David C., Ostuni, Emanuele, Willmore, Nikolaos D., Whitesides, George M.·1998·Analytical Chemistry

Abstract

This paper describes the fabrication of large (up to 45 cm(2)) arrays of microwells, with volumes as small as ∼3 fL/well and densities as high as 10(7) wells/cm(2). These arrays of microwells are formed by casting an elastomer, poly(dimethylsiloxane) (PDMS), against "masters" prepared by photolithography; arrays of microwells in other polymers can be formed by using a master consisting of posts in PDMS. A straightforward technique, discontinuous dewetting, allows wells to be filled rapidly (typically on the order of 10(4) wells/s) and uniformly with a wide range of liquids. Several rudimentary strategies for addressing microwells are investigated, including electroosmotic pumping and gaseous diffusion.

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Metadata

Authors
Jackman, R. J., Duffy, D. C., Ostuni, E., Willmore, N. D., & Whitesides, G. M.
Venue
Analytical Chemistry
Published
1998-05-01
Volume
70
Issue
11
Pages
2280-2287
ISSN
  • 0003-2700 (ISSN-L)
  • 1520-6882
OpenAlex
W2091697423
Cited by
304
References
1
FWCI
11.22
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Fabricating Large Arrays of Microwells with Arbitrary Dimensions and Filling Them Using Discontinuous Dewetting. https://app.cochat.ai/papers/10.1021/ac971295a
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Jackman, R. J., Duffy, D. C., Ostuni, E., Willmore, N. D., & Whitesides, G. M. (1998). Fabricating Large Arrays of Microwells with Arbitrary Dimensions and Filling Them Using Discontinuous Dewetting. Analytical Chemistry. https://doi.org/10.1021/ac971295a

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