The DOI matches its Crossref record; 278 of the 278 references it cites were found in a registry or an index.
Phase Transitions of Associative Biomacromolecules
Open accessAbstract
Multivalent proteins and nucleic acids, collectively referred to as multivalent associative biomacromolecules, provide the driving forces for the formation and compositional regulation of biomolecular condensates. Here, we review the key concepts of phase transitions of aqueous solutions of associative biomacromolecules, specifically proteins that include folded domains and intrinsically disordered regions. The phase transitions of these systems come under the rubric of coupled associative and segregative transitions. The concepts underlying these processes are presented, and their relevance to biomolecular condensates is discussed.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Room-Temperature Ionic Liquids: Solvents for Synthesis and Catalysis. 2
Hallett, J. P., & Welton, T. (2011) · Chemical Reviews · doi:10.1021/cr1003248 · Cited by 12,578
Room-Temperature Ionic Liquids. Solvents for Synthesis and Catalysis
Welton, T. (1999) · Chemical Reviews · doi:10.1021/cr980032t · Cited by 11,852
Biomolecular condensates: organizers of cellular biochemistry
Banani, S. F., Lee, H. O., Hyman, A. A., & Rosen, M. K. (2017) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.7 · Cited by 6,100
Rubinstein, M., & Colby, R. H. (2003) · doi:10.1093/oso/9780198520597.001.0001 · Cited by 5,686
Molecular thermodynamics of fluid-phase equilibria
Rowlinson, J. S. (1970) · The Journal of Chemical Thermodynamics · doi:10.1016/0021-9614(70)90078-9 · Cited by 5,424
THE EFFECTS OF SHAPE ON THE INTERACTION OF COLLOIDAL PARTICLES
Onsager, L. (1949) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1949.tb27296.x · Cited by 4,934
Thermodynamics of High Polymer Solutions
Flory, P. J. (1942) · The Journal of Chemical Physics · doi:10.1063/1.1723621 · Cited by 4,374
Liquid phase condensation in cell physiology and disease
Shin, Y., & Brangwynne, C. P. (2017) · Science · doi:10.1126/science.aaf4382 · Cited by 4,152
Theory of Microphase Separation in Block Copolymers
Leibler, L. (1980) · Macromolecules · doi:10.1021/ma60078a047 · Cited by 3,903
Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation
Brangwynne, C. P., Eckmann, C. R., Courson, D. S., Rybarska, A., Hoege, C., Gharakhani, J., Jülicher, F., & Hyman, A. A. (2009) · Science · doi:10.1126/science.1172046 · Cited by 3,202
Cited by
(2023) · doi:10.1038/s41467-023-41586-y · Cited by 118
Fluorescent protein and peptide tags alter condensate formation and dynamics in vivo and in vitro
Dörner, K., Gut, M. J., Overwijn, D., Cao, F., Siketanc, M., Heinrich, S., Beuret, N., Meyer, J., Sharpe, T., Lindorff-Larsen, K., et al. (2026) · EMBO Reports · doi:10.1038/s44319-025-00626-y · Cited by 45
(2025) · doi:10.1038/s41557-025-01847-3 · Cited by 40
Regulation of Peptide Liquid–Liquid Phase Separation by Aromatic Amino Acid Composition
Netzer, A., Baruch Leshem, A., Veretnik, S., Edelstein, I., & Lampel, A. (2024) · Small · doi:10.1002/smll.202401665 · Cited by 28
The filamentous ultrastructure of the PopZ condensate is required for its cellular function
Scholl, D., Boyd, T., Latham, A. P., Salazar, A., Khan, A. M. A. M., Boeynaems, S., Holehouse, A. S., Lander, G. C., Sali, A., Park, D., et al. (2026) · Nature Structural & Molecular Biology · doi:10.1038/s41594-025-01742-y · Cited by 14
Metadata
- Authors
- Pappu, R. V., Cohen, S. R., Dar, F., Farag, M., & Kar, M.
- Venue
- Chemical Reviews
- Publisher
- American Chemical Society (ACS)
- Published
- 2023-03-07
- Volume
- 123
- Issue
- 14
- Pages
- 8945-8987
- ISSN
- 0009-2665 (ISSN-L)
- 1520-6890
- OpenAlex
- W4323350303
- Cited by
- 367
- References
- 278
- FWCI
- 9.17
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Phase Transitions of Associative Biomacromolecules. https://app.cochat.ai/papers/10.1021/acs.chemrev.2c00814
- The paper
- Pappu, R. V., Cohen, S. R., Dar, F., Farag, M., & Kar, M. (2023). Phase Transitions of Associative Biomacromolecules. Chemical Reviews. https://doi.org/10.1021/acs.chemrev.2c00814
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
