Cited by 11Proteins in Food SystemsProtein Hydrolysis and Bioactive PeptidesProtein Interaction Studies and Fluorescence Analysis

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The Whey–Plant Protein Heteroprotein Systems with Synergistic Properties and Versatile Applications

Liu, Chang, Wang, Ruhua, Wang, Tianyang, Gu, Chunkai, Zhang, Lingling, Meng, Demei, Pan, Mingfei, Yang, Rui·2025·Journal of Agricultural and Food Chemistry

Abstract

Combining animal protein with plant protein is a feasible approach to provide heteroprotein formulations with versatile properties. This review introduces the interactions of typical protein whey protein (WP) from milk with soy protein (SP), pea protein (PP), rapeseed protein (RAP), lupine protein (LP), and rice protein (RIP) through physical and chemical methods. The characteristics of whey-plant protein complexes are described with particular emphasis on the protein types, structures, and properties. In addition, the factors that influence the formation of whey-plant complexes are reviewed. The potential food applications of whey-plant protein complexes are reviewed. Overcoming the shortcomings and future challenges for applications of the heteroprotein in the food field are highlighted. This review will fill the gap of whey protein and are important for the development of more versatile properties of whey proteins as well as a systematic understanding of the synergistic biological roles of these active proteins.

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Crossref · 10.1021/acs.jafc.4c10736

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Metadata

Authors
Liu, C., Wang, R., Wang, T., Gu, C., Zhang, L., Meng, D., Pan, M., & Yang, R.
Affiliations
Tianjin University of Science and Technology (CN)
Corresponding author
  • Meng, Demei
  • Pan, Mingfei
  • Yang, Rui
Venue
Journal of Agricultural and Food Chemistry
Published
2025-02-03
Volume
73
Issue
8
Pages
4440-4454
ISSN
  • 0021-8561 (ISSN-L)
  • 1520-5118
OpenAlex
W4407112904
Cited by
11
References
2
Citations by year
2026: 8 · 2025: 3
FWCI
0.81
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Agricultural and Food Chemistry (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Natural Science Foundation of China (31972067)
  • National Natural Science Foundation of Tianjin (23JCZDJC00610)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Proteins in Food Systems
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Protein Hydrolysis and Bioactive Peptides
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Interaction Studies and Fluorescence Analysis
Keywords
whey protein, plant proteins, protein-protein interaction, soy protein, pea protein, rapeseed protein, lupine protein, rice protein, protein structure, food applications, functional proteins
MeSH terms
Whey Proteins, Animals, Plant Proteins, Soybean Proteins

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