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Terahertz Wave Accelerates DNA Unwinding: A Molecular Dynamics Simulation Study
Abstract
Unwinding the double helix of the DNA molecule is the basis of gene duplication and gene editing, and the acceleration of this unwinding process is crucial to the rapid detection of genetic information. Based on the unwinding of six-base-pair DNA duplexes, we demonstrate that a terahertz stimulus at a characteristic frequency (44.0 THz) can serve as an efficient, nonthermal, and long-range method to accelerate the unwinding process of DNA duplexes. The average speed of the unwinding process increased by 20 times at least, and its temperature was significantly reduced. The mechanism was revealed to be the resonance between the terahertz stimulus and the vibration of purine connected by the weak hydrogen bond and the consequent break in hydrogen bond connections between these base pairs. Our findings potentially provide a promising application of terahertz technology for the rapid detection of nucleic acids, biomedicine, and therapy.
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., Zhang, L., Fan, G., Xu, J., Gu, X., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30183-5 · Cited by 48,884
Abraham, M. J., Murtola, T., Schulz, R., Páll, S., Smith, J. C., Hess, B., & Lindahl, E. (2015) · SoftwareX · doi:10.1016/j.softx.2015.06.001 · Cited by 27,190
Swope, W. C., Andersen, H. C., Berens, P. H., & Wilson, K. R. (1982) · The Journal of Chemical Physics · doi:10.1063/1.442716 · Cited by 4,051
Rattle: A “velocity” version of the shake algorithm for molecular dynamics calculations
Andersen, H. C. (1983) · Journal of Computational Physics · doi:10.1016/0021-9991(83)90014-1 · Cited by 3,081
A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics
SantaLucia, J. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.4.1460 · Cited by 2,793
Genetical Implications of the Structure of Deoxyribonucleic Acid
WATSON, J. D., & CRICK, F. H. C. (1953) · Nature · doi:10.1038/171964b0 · Cited by 2,197
Foloppe, N., & MacKerell, Jr. (2000) · Journal of Computational Chemistry · doi:10.1002/(sici)1096-987x(20000130)21:2<86::aid-jcc2>3.0.co;2-g · Cited by 1,582
DNA sensing by the cGAS–STING pathway in health and disease
Motwani, M., Pesiridis, S., & Fitzgerald, K. A. (2019) · Nature Reviews Genetics · doi:10.1038/s41576-019-0151-1 · Cited by 1,467
de Leeuw, S. W., Perram, J. W., & Smith, E. R. (1980) · Proceedings of the Royal Society of London. A. Mathematical and Physical Sciences · doi:10.1098/rspa.1980.0135 · Cited by 1,353
TRANSCRIPTION OF EUKARYOTIC PROTEIN-CODING GENES
Lee, T. I., & Young, R. A. (2000) · Annual Review of Genetics · doi:10.1146/annurev.genet.34.1.77 · Cited by 860
Metadata
- Authors
- Wu, K., Qi, C., Zhu, Z., Wang, C., Song, B., & Chang, C.
- Venue
- The Journal of Physical Chemistry Letters
- Publisher
- American Chemical Society (ACS)
- Published
- 2020-08-03
- Volume
- 11
- Issue
- 17
- Pages
- 7002-7008
- ISSN
- 1948-7185 (ISSN-L)
- OpenAlex
- W3047487730
- Cited by
- 305
- References
- 27
- FWCI
- 4.70
- Type
- journal article
- Language
- en
- Open access
- closed
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