The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.
Green Synthesis of Fluorescent Carbon Dots from Gynostemma for Bioimaging and Antioxidant in Zebrafish
Abstract
Fluorescent carbon dots (CDs) have been synthesized via the calcination method using natural gynostemma as the precursor, without any toxic ingredients or surface passivation chemicals. CDs have a narrow size distribution, and the mean particle size is about 2.5 nm. CDs exhibit good water dispersibility and can emit intense blue fluorescence under 365 nm UV light in an aqueous solution, which can be stable in different conditions. The biotoxicity of CDs on the embryonic development of zebrafish is evaluated, the hatch rate and survival rate of embryos are around 90%, and the malformation rate is less than 10%. Because of the excellent fluorescence stability and biocompatibility, CDs can be used in zebrafish for bioimaging. In addition, the antioxidative stress property of CDs is investigated both in vitro and in vivo, and the presence of CDs can promote the mRNA expression of related genes to encode more antioxidant proteins in zebrafish. Therefore, fluorescent CDs would be a potential candidate for bioimaging and treating diseases caused by excessive oxidation damage, such as cancer, senility, and other diseases associated with aging.
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Cites
Electrophoretic Analysis and Purification of Fluorescent Single-Walled Carbon Nanotube Fragments
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Quantum-Sized Carbon Dots for Bright and Colorful Photoluminescence
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Self-citation
Cited by
Carbon Dots: A New Type of Carbon-Based Nanomaterial with Wide Applications
Liu, J., Li, R., & Yang, B. (2020) · ACS Central Science · doi:10.1021/acscentsci.0c01306 · Cited by 1,936
Self-citationBiomass-Based Carbon Dots: Current Development and Future Perspectives
Wareing, T. C., Gentile, P., & Phan, A. N. (2021) · ACS Nano · doi:10.1021/acsnano.1c03886 · Cited by 665
Properties, synthesis, and applications of carbon dots: A review
Ozyurt, D., Kobaisi, M. A., Hocking, R. K., & Fox, B. (2023) · Carbon Trends · doi:10.1016/j.cartre.2023.100276 · Cited by 640
Applications of carbon dots in environmental pollution control: A review
Long, C., Jiang, Z., Shangguan, J., Qing, T., Zhang, P., & Feng, B. (2021) · Chemical Engineering Journal · doi:10.1016/j.cej.2020.126848 · Cited by 434
Nguyen, D. D., & Lai, J.-Y. (2022) · Chemical Engineering Journal · doi:10.1016/j.cej.2022.134970 · Cited by 178
Metadata
- Authors
- Wei, X., Li, L., Liu, J., Yu, L., Li, H., Cheng, F., Yi, X., He, J., & Li, B.
- Venue
- ACS Applied Materials & Interfaces
- Publisher
- American Chemical Society (ACS)
- Published
- 2019-02-13
- Volume
- 11
- Issue
- 10
- Pages
- 9832-9840
- ISSN
- 1944-8244 (ISSN-L)
- 1944-8252
- OpenAlex
- W2912274077
- Cited by
- 257
- References
- 46
- FWCI
- 11.29
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wei, X., Li, L., Liu, J., Yu, L., Li, H., Cheng, F., Yi, X., He, J., & Li, B. (2019). Green Synthesis of Fluorescent Carbon Dots from Gynostemma for Bioimaging and Antioxidant in Zebrafish. ACS Applied Materials & Interfaces. https://doi.org/10.1021/acsami.9b00074
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