Polysarcosine-functionalized lipid nanoparticles for therapeutic mRNA delivery

Nogueira, Sara S., Schlegel, Anne, Maxeiner, Konrad, Weber, Benjamin, Barz, Matthias, Schroer, Martin A., Blanchet, Clement E., Svergun, Dmitri I. +5 more·2020·ACS Applied Nano Materials

Cited by (252)

Items 101–200 of 252

  1. Advances in engineered nanosystems: immunomodulatory interactions for therapeutic applications
    Rupam Khatua, Bibrita Bhar, Souradeep Dey, Chitra Jaiswal, Jorge I. Victoria, Biman B. Mandal · 2024 · Nanoscale
  2. Recent Advances in Lipid Nanoparticles: Nucleic Acid Therapeutics and Targeting Strategies
    Sharat Sarmah, Sourav Baidya, Mrinmoy De · 2025 · Small
  3. Material Design for Next-Generation mRNA Vaccines Using Lipid Nanoparticles
    Akon Higuchi, Tzu‐Cheng Sung, Ting Wang, Qing‐Dong Ling, Suresh S. Kumar, Shih-Tien Hsu, Akihiro Umezawa · 2022 · Journal of macromolecular science. Part C, Reviews in macromolecular chemistry and physics/Journal of macromolecular science. Reviews in macromolecular chemistry and physics
  4. Poly(2-methyl-2-oxazoline) as a polyethylene glycol alternative for lipid nanoparticle formulation
    Dwain George van Zyl, Livia Palmerston Mendes, Raphaela P. Semper, Christine Rueckert, Patrick Baumhof · 2024 · Frontiers in Drug Delivery
  5. Cyclic Poly(2-methyl-2-oxazoline)-Lipid Conjugates Are Good Alternatives to Poly(ethylene glycol)-Lipids for Lipid Nanoparticle mRNA Formulation
    Bianka Golba, Zifu Zhong, Matteo Romio, Ruben Almey, Dieter L. D. Deforce, Maarten Dhaenens, Niek N. Sanders, Edmondo Maria Benetti, Bruno G. De Geest · 2025 · Biomacromolecules
  6. The impact of chemical reactivity on the quality and stability of RNA–LNP pharmaceuticals
    Tristan Kovačič, Heinrich Haas, Lior Stotsky‐Oterin, Aleš Štrancar, Urban Bren, Dan Peer · 2025 · Nature Reviews Chemistry
  7. Designing Highly Stable Poly(sarcosine)-Based Telodendrimer Micelles with High Drug Content Exemplified with Fulvestrant
    Qing Bo Yu, R. England, Anders Gunnarsson, Robert Luxenhofer, Kevin Edward Treacher, Marianne B. Ashford · 2022 · Macromolecules
  8. Π-Π interactions stabilize PeptoMicelle-based formulations of Pretomanid derivatives leading to promising therapy against tuberculosis in zebrafish and mouse models
    Nils‐Jørgen Knudsen Dal, Gabriela Giannina Schäfer, Andrew M. Thompson, Sascha Schmitt, Natalja Redinger, Noelia Alonso‐Rodríguez, Kerstin Johann, Jessica Ojong, Jens Wohlmann, Andreas Best et al. · 2023 · Journal of Controlled Release
  9. Emerging Strategies for Immunotherapy of Solid Tumors Using Lipid‐Based Nanoparticles
    Soraia Fernandes, Marco Cassani, Francesca Cavalieri, Giancarlo Forte, Frank Caruso · 2023 · Advanced Science
  10. The Production of Polysarcosine‐Containing Nanoparticles by Ring‐Opening Polymerization‐Induced Self‐Assembly
    Anna H. Morrell, Nicholas J. Warren, Paul D. Thornton · 2024 · Macromolecular Rapid Communications
  11. Emerging lipid–polymer hybrid nanoparticles for genome editing
    Mariana d'Almeida Gameiro, João Filipe Mano, Vítor M. Gaspar · 2024 · Polymer Chemistry
  12. Polypeptoids and Peptoid–Peptide Hybrids by Transition Metal Catalysis
    Zachary S. Clauss, Jessica R. Kramer · 2021 · ACS Applied Materials & Interfaces
  13. Photocleavable core cross-linked polymeric micelles of polypept(o)ides and ruthenium( ii ) complexes
    Tobias Alexander Bauer, Jonas Eckrich, Nadine Wiesmann, Felix Kuczelinis, Wen Ce Sun, Xiaolong Zeng, Benjamin Weber, Si Wu, Nicolas H. Bings, Sebastian Strieth et al. · 2021 · Journal of Materials Chemistry B
  14. Polysarcosine functionalised cationic polyesters efficiently deliver self-amplifying mRNA
    Hulya Bayraktutan, Rafał Jerzy Kopiasz, Amr Elsherbeny, Magda Martínez-Espuga, Nurcan Gümüş, Umut Can Öz, Krunal Polra, Paul F. McKay, Robin J. Shattock, Paloma Ordóñez‐Morán et al. · 2024 · Polymer Chemistry
  15. Discovery of a Peptoid-Based Nanoparticle Platform for Therapeutic mRNA Delivery via Diverse Library Clustering and Structural Parametrization
    Elizabeth R. Webster, Nicole E. Peck, Juan Diego Echeverri, Shima Gholizadeh, Wei-Lun Tang, Rinette W.L. Woo, Anushtha Sharma, Weiqun Liu, Chris S. Rae, Adrienne Sallets et al. · 2024 · ACS Nano
  16. Critical considerations of mRNA–LNP technology for CAR-T therapy: components, payloads and emerging horizons
    Yunfeng Qu, Renfa Liu, Desheng Sun, Zhifei Dai · 2024 · Materials Chemistry Frontiers
  17. Lipid-Polyhydroxyalkanoate Hybrid Nanoparticles as Sustainable Platform for mRNA delivery
    Zihnil Adha Islamy Mazrad, Chee Leng Lee, Tianxia Zhang, Nicole M. Warne, Nhu Thao Huynh, Md. Shahruk Nur‐A‐Tomal, Neil R. Cameron, Leonie van ‘t Hag, Colin William Pouton, Kristian Kempe · 2025 · European Journal of Pharmaceutics and Biopharmaceutics
  18. Form factor determination of biological molecules with X-ray free electron laser small-angle scattering (XFEL-SAS)
    Clement Emmanuel Blanchet, Adam R. Round, Haydyn D. T. Mertens, Kartik Ayyer, Melissa Ann Graewert, Salah Awel, Daniel Franke, Katerina Dörner, S. Bajt, Richard Bean et al. · 2023 · Communications Biology
  19. Polypeptides as alternatives to PEGylation of therapeutic agents
    Huali Chen, Qianyu Zhang · 2023 · Expert Opinion on Drug Delivery
  20. Better, Faster, Stronger: Accelerating mRNA ‐Based Immunotherapies With Nanocarriers
    Henrique Carvalho, Tiago A. S. Fidalgo, Rita C. Acúrcio, Ana I. Matos, Ronit Satchi‐Fainaro, Helena F. Florindo · 2024 · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
  21. The influence of protein corona on liposomal delivery systems: A comprehensive review
    Solmaz Mojarad-Jabali, Yousef Fatahi, Rassoul Dinarvand · 2025 · European Journal of Pharmaceutical Sciences
  22. Lipoplexes and polyplexes as nucleic acids delivery nanosystems: The current state and future considerations
    Bruno Costa, Beatriz Boueri, Claudia L. Oliveira, Isabel Silveira, António José Ribeiro · 2022 · Expert Opinion on Drug Delivery
  23. mRNA therapeutics for disease therapy: principles, delivery, and clinical translation
    Dawei Zhou, Ke Wang, Ying‐Ao Zhang, Ke Ma, Xiaochun Yang, Zhen-Yi Li, Shoushan Yu, Kezheng Chen, Sheng‐Lin Qiao · 2023 · Journal of Materials Chemistry B
  24. Lipid nanoparticles: A delicate nucleic acid delivery system to be further explored
    Runpu Ma, Yuting Li, Yang Su, Peng Chen, Sitao Xie, Weihong Tan, Xiangsheng Liu · 2024 · Nano Today
  25. Direct structural investigation of pH responsiveness in mRNA lipid nanoparticles: Refining paradigms
    Christoph Wilhelmy, Lukas Uebbing, Bastian Kolb, Melissa Ann Graewert, Thomas Nawroth, Heinrich Haas, Peter Langguth · 2025 · Journal of Controlled Release
  26. Engineered Antifouling Peptides with Sarcosine Branches for Robust Electrochemical Detection of the HER2 Biomarker in Real Biological Samples
    Hao Zhou, Mingjun Shi, Wenhao Yang, Ning Song, Xiliang Luo · 2025 · ACS Sensors
  27. Implications of Anaphylaxis Following mRNA-LNP Vaccines: It Is Urgent to Eliminate PEG and Find Alternatives
    Jinxing Song, Dihan Su, Hongbing Wu, Jeremy Guo · 2025 · Pharmaceutics
  28. Biomaterial-Mediated Protein Expression Induced by Peptide-mRNA Nanoparticles Embedded in Lyophilized Collagen Scaffolds
    Rik Oude Egberink, Helen M. Zegelaar, Najoua El Boujnouni, Elly M. M. Versteeg, Willeke F. Daamen, Roland E. Brock · 2022 · Pharmaceutics
  29. Tuning the Cross-Linking Density and Cross-Linker in Core Cross-Linked Polymeric Micelles and Its Effects on the Particle Stability in Human Blood Plasma and Mice
    Tobias Alexander Bauer, Irina Alberg, Lydia Zengerling, Pol Besenius, Kaloian Koynov, Bram Slütter, Rudolf Zentel, Ivo Que, Heyang Zhang, Matthias Barz · 2023 · Biomacromolecules
  30. Toward Quantitative End-Group Fidelity in the Synthesis of High Molecular Weight Polysarcosine
    Zlata Nagorna, Matthias Barz, Joachim F. R. Van Guyse · 2025 · ACS Macro Letters
  31. Polyglycerol‐Based Lipids: A Next‐Generation Alternative to PEG in Lipid Nanoparticles for Advanced Drug Delivery Systems
    Yara Ensminger, Rashmi Rashmi, Michael Karimov, Gideon Nölte, Markus Hafke, Ann‐Cathrin Schmitt, Christian David Díaz‐Oviedo, Johannes Köbberling, Rainer Haag · 2025 · Macromolecular Rapid Communications
  32. Crafting Stable Antibiotic Nanoparticles via Complex Coacervation of Colistin with Block Copolymers
    Thomas Daniel Vogelaar, Anne Eriksson Agger, Janne Elin Reseland, Dirk Linke, Håvard Jenssen, Reidar Lund · 2024 · Biomacromolecules
  33. Recyclable Polythioesters and Poly(thioester‐co‐peptoid)s via Ring‐Opening Cascade Polymerization of Amino Acid N ‐Carboxyanhydrides
    Shuo Wang, Zi‐You Tian, Hua Lu · 2024 · Angewandte Chemie International Edition
  34. [11C]Carboxylated Tetrazines for Facile Labeling of Trans‐Cyclooctene‐Functionalized PeptoBrushes
    Rocío García Vázquez, Umberto Maria Battisti, Vladimir Shalgunov, Gabriela Giannina Schäfer, Matthias Barz, Matthias M. Herth · 2021 · Macromolecular Rapid Communications
  35. Navigating the Biomolecular Corona: Biological Interactions and Therapeutic Implications of RNA–Lipid Nanoparticles
    Anamika Saini, Shiyao Li, Zhaoran Wang, Magdalena Plebanski, Yi Ju · 2026 · ACS Nano
  36. On the origin of the low immunogenicity and biosafety of a neutral α-helical polypeptide as an alternative to polyethylene glycol
    Jialing Sun, Junyi Chen, Yiming Sun, Yingqin Hou, Zhibo Liu, Hua Lu · 2023 · Bioactive Materials
  37. The optimization strategies of LNP-mRNA formulations: Development and challenges for further application
    Sizhen Wang, Beibei Guo, Huan Wang, Feng Yang · 2024 · Journal of Drug Delivery Science and Technology
  38. Molecular Dynamics Simulation of Lipid Nanoparticles Encapsulating mRNA
    Zhigang Zhang, Dazhi Cheng, Wenqin Luo, Donling Hu, Tiantian Yang, Kaixuan Hu, Li Liang, Wei Liu, Jianping Hu · 2024 · Molecules
  39. Enhancing antitumor immunity through chemotherapeutic-derived lipid nanoparticle-induced immunogenic cell death and CD40L/Flt3L mRNA-mediated dendritic cell activation
    Xucheng Hou, Chang Wang, Yichen Zhong, Leiming Wang, Diana D. Kang, Gabrielle S. Lubitz, Yonger Xue, Zhengwei Liu, Siyu Wang, Haoyuan Li et al. · 2025 · Journal of Controlled Release
  40. A Molecular View of Lipid Nanoparticles: Insights into their Morphology and Structural Plasticity
    Sudha Porte, V Vadhana, Durba Sengupta · 2025 · Small
  41. A PEG-lipid-free COVID-19 mRNA vaccine triggers robust immune responses in mice
    Min Li, Yixuan Huang, Jiacai Wu, Sanpeng Li, Miao Mei, Haixia Chen, Ning Wang, Weigang Wu, Boping Zhou, Xu Tan et al. · 2022 · Materials Horizons
  42. Anti-PEG antibodies in nanomedicine: Mechanisms, risks, and opportunities
    Suyama Prasansali Mihindukulasooriya, Zhaoran Wang, Shiyao Li, Anamika Saini, Kirsty Wilson, Magdalena Plebanski, Stephen J. Kent, Yi Ju · 2026 · Advanced Drug Delivery Reviews
  43. Cross‐Linkable Polyion Complex Micelles from Polypept(o)ide‐Based ABC‐Triblock Copolymers for siRNA Delivery
    Leon Capelôa, Mina Yazdi, Heyang Zhang, Xiaobing Chen, Yu Nie, Ernst Wagner, Ulrich Lächelt, Matthias Barz · 2021 · Macromolecular Rapid Communications
  44. Novel Lipid Nanoparticle (LNP) Delivery Systems Enabling the Advancement of RNA Therapeutics
    Honglei Zhang, Shaowei Han, Xueyan Zhang, Jingxuan Ma, Lijie Jin, Yanfeng Wang, Yuqing Ma, Teng Ma, Fei Yu, Gengshen Song · 2026 · Advanced Healthcare Materials
  45. Well‐Defined Anisotropic Self‐Assembly from Peptoids and Their Biomedical Applications
    Yota Okuno, Yasuhiko Iwasaki · 2023 · ChemMedChem
  46. Bioinspired and bioengineered nucleic acid drug carriers
    Jiamin Zuo, Zhiguo Lü, Jing Ru Guo, Ruichen Zhao, Tianlu Zhang, Zhaoxia Wang, Yun Fei Yuan, Jianwen Deng, Junliang Yuan, Xin Zhang · 2024 · Science China Materials
  47. Technological breakthroughs and advancements in the application of mRNA vaccines: a comprehensive exploration and future prospects
    Zhimeng Wei, Shuai Zhang, Xingya Wang, Ying Xue, Sheng Dang, Jingbo Zhai · 2025 · Frontiers in Immunology
  48. Bispecific antibodies and nanotechnology: a strategic alliance in cancer immunotherapy
    Elisa Battistini, Philipp Lapuhs, Alberto Jiménez, Sergio Garrido-Areal, Lucía Rivas-Gómez, Ivana Zagorac, Luis Álvarez‐Vallina, Marı́a José Alonso, Lucía Sanjurjo · 2025 · Molecular Cancer
  49. Deciphering the biological fate of mRNA-LNP-based biologics: A perspective from tissue to intracellular distribution
    Xu, Xin, Cui, Lili, Zhang, Yong, Gu, Jingkai · 2026 · Acta Pharmaceutica Sinica B
  50. The Kinetic Pathways for the Formation of Complex Coacervate Micelles of Antimicrobial Peptides and Block Copolymers
    Thomas Daniel Vogelaar, Henrik Martin Hansen Torjusen, Theyencheri Narayanan, Reidar Lund · 2024 · Macromolecules
  51. PEG‐Free Monosialoganglioside Lipid Nanoparticles with Spleen‐Selective mRNA Delivery for Cancer Immunotherapy
    Ziqian Wang, Xingwu Liu, Jiahui Jin, Xiaoyi Liu, Cong Liu, Fengfei Xie, Xingyun Wang, Fangjie An, Bao Xiao, Hanchao Cheng et al. · 2025 · Advanced Functional Materials
  52. Designing around immune memory to counter PEG immunogenicity
    Namit Chaudhary, Kathryn A. Whitehead · 2025 · Nature Materials
  53. Overcoming the PEG dilemma with Poly(2-ethyl-2-oxazoline) lipids in lipid nanoparticle formulations
    Randall W. Moreadith, Wookhyun Kim, Kelley Smith, Kunsang Yoon, Rebecca Weimer, Zhihao Fang · 2025 · European Polymer Journal
  54. Novel lipid nanoparticle provides potent SARS-CoV-2 mRNA vaccine at low dose with low local reactogenicity, high thermostability and limited systemic biodistribution
    Suman Alishetty, Manuel J. Carrasco, Mohamad‐Gabriel Alameh, Mikell A. Paige, Hooda Said, Lacey Wright, Aarthi Narayanan, Farhang Alem, Keziah R. Hernandez, Patrick Martin Gillevet et al. · 2021 · Research Square
  55. Influence of structural variations in polysarcosine functionalized lipids on lipid nanoparticle‐mediated mRNA delivery
    Runcheng Tan, Guangqi Huang, Cong Wei, Zepeng He, Tianyu Zhao, Yi Shi, Zhijia Liu, Yongming Chen · 2024 · Journal of Polymer Science
  56. Nano-immunotherapeutic strategies for targeted RNA delivery: Emphasizing the role of monocyte/macrophages as nanovehicles to treat glioblastoma multiforme
    Amanda-Lee Ezra Manicum, Saman Sargazi, Sobia Razzaq, Govindarajan Venkat Kumar, Abbas Rahdar, Simge Er Zeybekler, Qurrat Ul Ain, Muhammad Bilal, M. Ali Aboudzadeh · 2022 · Journal of Drug Delivery Science and Technology
  57. ACE mRNA (Additional Chimeric Element incorporated IVT mRNA) for Enhancing Protein Expression by Modulating Immunogenicity
    Sora Son, Minsa Park, Jin Kuk Kim, Kyuri Lee · 2024 · Advanced Science
  58. Utility of Triethyloxonium Tetrafluoroborate for Chloride Removal during Sarcosine N‐Carboxyanhydride Synthesis: Improving NCA Purity
    Leon Capelôa, Rafael Miravet Martí, Aroa Duro‐Castaño, Vicent J. Nebot, Matthias Barz · 2024 · Chemistry - A European Journal
  59. Miktoarm Star-polypept(o)ide-Based Polyion Complex Micelles for the Delivery of Large Nucleic Acids
    David Schwiertz, Jennifer Angelina, Heyang Zhang, Matthias Barz · 2024 · Biomacromolecules
  60. Ganglioside-incorporating lipid nanoparticles as a polyethylene glycol-free mRNA delivery platform
    Yafi S. Permana, Mincheol Jang, Kyunghwan Yeom, Erinn Fagan, Jin Hyoung Kim, Jisik Choi, Ji‐Ho Park · 2025 · Biomaterials Science
  61. Electron‐Deficient Alkyne Lipids Enable Efficient Synthesis of Comparable Polymer Lipids via Copper‐Free Azide‐Alkyne Cycloaddition
    Florian T. Kaps, Anna‐Lena Ziegler, Paul Fritsche, Ekaterina Takmakova, Andrew Kerr, Susanne Boye, Albena Lederer, Robert Luxenhofer · 2025 · Angewandte Chemie International Edition
  62. Poly(sarcosine) and Poly(2-ethyl-2-oxazoline) Tethered To mRNA Provide Stealth Properties To mRNA Polyplexes
    Victor Marx, Yuki Mochida, Shigehito Osawa, Theofilus A. Tockary, Jumpei Norimatsu, Hidetomo Yokoo, Makoto Oba, Satoshi Uchida · 2025 · ACS Applied Nano Materials
  63. Inflammatory and immune-mediated toxicity of lipid nanoparticles
    Soyeon Kim, Choeun Park, Yeji Lee, Kunwoo Lee, Hyukjin Lee, K. Lee · 2026 · Biomedicine & Pharmacotherapy
  64. Towards mRNA therapeutics 2.0
    Kenneth R. Chien, Kylie S. Foo, Nevin Witman · 2026 · Nature Reviews Drug Discovery
  65. Reversible transformation of peptide assembly between densified-polysarcosine-driven kinetically and helix-orientation-driven thermodynamically stable morphologies
    Mohamed S. Elafify, Toru Itagaki, Nermeen Adel ElKasabgy, Sinar Sayed, Yoshihiro Ito, Motoki Ueda · 2023 · Biomaterials Science
  66. Membrane-active diacylglycerol-terminated thermoresponsive polymers: RAFT synthesis and biocompatibility evaluation
    Izabela Kurowska, Karolina Halina Markiewicz, Katarzyna Niemirowicz-Laskowska, Paweł Misiak, Mathias Destarac, Przemysław Wielgat, Iwona Misztalewska‐Turkowicz, Gabriela Siemiaszko, Halina Car, Agnieszka Zofia Wilczewska · 2022 · European Polymer Journal
  67. The benefits of emerging alternatives to PEG for lipid nanoparticle RNA delivery systems
    Manon Berger, Manon Degey, Alicia Curnel, Brigitte Évrard, Géraldine Piel · 2025 · Nanomedicine
  68. Solid Lipid Nanoparticles Coated with Glucosylated poly(2-oxazoline)s: A Supramolecular Toolbox Approach
    Johanna K. Elter, František Sedlák, Tomáš Palušák, Nicol Bernardová, Volodymyr Lobaz, Eva Tihlaříková, Vilém Neděla, Pavel Šácha, Martin Hrubý · 2025 · Biomacromolecules
  69. Molecular localization and exchange kinetics in pharmaceutical liposome and mRNA lipoplex nanoparticle products determined by small angle X-ray scattering and pulsed field gradient NMR diffusion measurements
    Daniel Schlattmann, Benjamin Weber, Leonard Wyszynski, Monika Schönhoff, Heinrich Haas · 2024 · European Journal of Pharmaceutics and Biopharmaceutics
  70. Tailoring Lipid-Based Drug Delivery Nanosystems by Synchrotron Small Angle X-ray Scattering
    Barbara Sartori, Benedetta Marmiroli · 2022 · Pharmaceutics
  71. The role of excipients in lipid nanoparticle metabolism: implications for enhanced therapeutic effect
    Karlene L. M. Knaggs, Yikai Sun, Brianna A. Walz, Janice Pang, Omar F. Khan · 2025 · Therapeutic Delivery
  72. Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects
    Yu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li, Zhiyong Tang · 2026 · Cancer Nexus
  73. Nanoparticle Clearance and New Horizons in Engineered Drug Delivery
    Bryan James Mathis, Alexander Zaboronok, Ying Shi, Yoshiyuki Nagumo, Hiroyuki Nishiyama, Yuji Hiramatsu · 2026 · Pharmaceutics
  74. Unlocking the potential of nanocarrier-mediated mRNA delivery across diverse biomedical frontiers: A comprehensive review
    Smita Pawar, Prashant Pingale, Atul Garkal, Riyaz Ali M. Osmani, Kavita Rai Gajbhiye, Madhur Kulkarni, Krutika Pardeshi, Tejal A Mehta, Amarjitsing Rajput · 2024 · International Journal of Biological Macromolecules
  75. Simple Scattering: Lipid nanoparticle structural data repository
    Lee Joon Kim, David S. Shin, Wellington Claiton Leite, Hugh O’Neill, Oliver Ruebel, Andrew Tritt, Greg L. Hura · 2024 · Frontiers in Molecular Biosciences
  76. Ethylene oxide graft copolymers reduce the immunogenicity of lipid nanoparticles
    Ya‐Lin Qi, Hesong Han, Albert K. Liu, Sheng Zhao, Atip Lawanprasert, Josefine Eilsø Nielsen, Hema Choudhary, Dengpan Liang, Annelise E. Barron, Niren Murthy · 2024 · RSC Advances
  77. Optimizing the targeting of lipid nanoparticles for gene therapy
    Lei Yue, Xiulei Gao, Wei Qi, Luhong Zhang, Yuefei Wang · 2025 · Nanoscale Horizons
  78. Overcoming PEG Antigenicity: Statistical PEG Isomers Reduce Antibody Binding
    Mareike Deuker, Dominik Schulz, Kaloian Koynov, Svenja Morsbach, Holger Frey, Katharina Landfester · 2025 · Advanced Science
  79. Nanomaterial-enabled RNA therapeutics: bridging delivery barriers to clinical translation
    Kshipra Pandey, Sneha Jha, Loka Bikash Chaliha, Haren B. Gosai, Ritu Patel · 2026 · Frontiers in Nanotechnology
  80. Beyond PEG: Emerging Polymer Lipid Alternatives for Lipid Nanoparticle (LNP) Formulations
    Zihnil Adha Islamy Mazrad, Yi Ju, Stephen John Kent, Colin William Pouton, Kristian Kempe · 2026 · Advanced Science
  81. Visible Light Conjugation with Triazolinediones as a Route to Degradable Poly(ethylene glycol)–Lipids for mRNA Lipid Nanoparticle Formulation
    Bianka Golba, Matthieu Soete, Zifu Zhong, Niek N. Sanders, Filip Du Prez, Hannes A. Houck, Bruno G. De Geest · 2023 · Angewandte Chemie
  82. Synthetic-polymer-assisted antisense oligonucleotide delivery: targeted approaches for precision disease treatment
    Ana Cubillo Alvarez, Dylan Maguire, Ruairí P. Brannigan · 2025 · Beilstein Journal of Nanotechnology
  83. Combining Core Cross-Linking and π–π-Interactions in Polymer Micelles Based on Polypept(o)ide AB3 Miktoarm Star Polymers
    David Schwiertz, Gabriela Giannina Schäfer, Matthias Barz · 2025 · Macromolecules
  84. Polypept(o)ide Based Biodegradable Cylindrical Polymer Brushes: Controlling Size, Shape, Surface Functionality, and Stability
    Christine Ilona Seidl, Bonan Zhao, Xinye Gao, Rüdiger Berger, Lin Jian, Kaloian Koynov, Meike Gangluff, Rivka Fontijn, Lu Su, Jeroen Bussmann et al. · 2025 · ACS Applied Materials & Interfaces
  85. Controlled Synthesis and Properties of Poly( l -homoserine)
    Isaac Benavides, Timothy J. Deming · 2023 · ACS Macro Letters
  86. From Self‐Organization to Tumor‐Immune Therapy: How Things Started and How They Evolved
    Matthias Barz, Lutz Nuhn, Gerhard Hörpel, Rudolf Zentel · 2022 · Macromolecular Rapid Communications
  87. The RNA delivery dilemma—lipid versus polymer nanoparticle platforms
    Cláudia Martins, Michael J. Mitchell, Dan Peer, Yvonne Perrie, Daniel J. Siegwart, Marı́a José Alonso, Juan Aparicio-Blanco · 2026 · Drug Delivery and Translational Research
  88. pH-Dependent Solution Micellar Structure of Amphoteric Polypeptoid Block Copolymers with Positionally Controlled Ionizable Sites
    Meng Zhang, Yun Liu, Xiaobing Zuo, Shuo Qian, Sai Venkatesh Pingali, Richard E. Gillilan, Qingqiu Huang, Donghui Zhang · 2023 · Biomacromolecules
  89. Polypept(o)ide‐Based Core–Shell Bottlebrush Polymers: A Versatile Platform for Drug Encapsulation
    Bonan Zhao, Jingyuan Wei, Rüdiger Berger, Lin Jian, Kaloian Koynov, Heyang Zhang, Matthias Barz · 2025 · Macromolecular Bioscience
  90. Chemische Ansätze für synthetische Wirkstofftransportsysteme für systemische Anwendungen
    Daniel Braatz, Mariam Cherri, Michael Tully, Mathias Dimde, Guoxin Ma, Ehsan Mohammadifar, Felix Reisbeck, Vahid Ahmadi, Michael Schirner, Rainer Haag · 2022 · Angewandte Chemie
  91. Synthesis of Heterotelechelic Poly( N ‐ethylglycine) Polymers: from Polypeptoid Lipid Conjugates to Protein‐Polymer Conjugates
    Ewout Buijs, Zlata Nagorna, Joachim F. R. Van Guyse, Matthias Barz · 2025 · Macromolecular Rapid Communications
  92. A modular polymer platform for efficient mRNA delivery in cancer immunotherapy
    Guanyou Lin, Jianxi Huang, Xinqi Li, Yunshan Liu, Taylor Juenke, Arthur Finstad, Miqin Zhang · 2025 · Nanoscale Horizons
  93. Polypeptide-engineered lipid nanoparticles for mRNA delivery with limited immunogenicity
    Jin‐Yue Zeng, Yue Zhang, Gui Zhao, Brandon Yi Loong Seow, Nithiyaa Balakrishnan, Jin Hao Goh, Yi Yan Yang · 2026 · Nature Communications
  94. Recyclable Polythioesters and Poly(thioester‐co‐peptoid)s via Ring‐Opening Cascade Polymerization of Amino Acid N‐Carboxyanhydrides
    Shuo Wang, Zi‐You Tian, Hua Lu · 2024 · Angewandte Chemie
  95. Self‐Assembled Nanocarriers of Synthetic and Natural Plasmalogens for Potential Nanomedicine Development
    Yu Wu, Borislav Angelov, Yuru Deng, Takehiko Fujino, Md. Shamim Hossain, Thomas Bizien, Angelina Angelova · 2024 · Advanced Therapeutics
  96. A Transient Initiator for Polypeptoids Postpolymerization α ‐Functionalization via Activation of a Thioester Group
    Solomiia Borova, Christine Schlutt, Joachim Nickel, Robert Luxenhofer · 2021 · Macromolecular Chemistry and Physics
  97. Advanced sample environments and sample requirements for biological SAXS
    Melissa Ann Graewert, Dmitri I. Svergun · 2022 · Methods in enzymology on CD-ROM/Methods in enzymology
  98. Knowledge-Based Design of Multifunctional Polymeric Nanoparticles
    Mira Behnke, Caroline T. Holick, Antje Vollrath, Stephanie Schubert, Ulrich S. Schubert · 2023 · Handbook of experimental pharmacology
  99. Electron‐Deficient Alkyne Lipids Enable Efficient Synthesis of Comparable Polymer Lipids via Copper‐Free Azide‐Alkyne Cycloaddition
    Florian T. Kaps, Anna‐Lena Ziegler, Paul Fritsche, Ekaterina Takmakova, Andrew Kerr, Susanne Boye, Albena Lederer, Robert Luxenhofer · 2025 · Angewandte Chemie
  100. Pioneering next-generation mRNA therapeutics through molecular engineering and delivery optimization
    Lin Qi, Zhihong Li, Zunyong Feng, Jianping Liu, Xiaoyuan Shawn Chen · 2025 · Materials Today