The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Playing with the Molecules of Life
Open accessAbstract
Our understanding of the complex molecular processes of living organisms at the molecular level is growing exponentially. This knowledge, together with a powerful arsenal of tools for manipulating the structures of macromolecules, is allowing chemists to to harness and reprogram the cellular machinery in ways previously unimaged. Here we review one example in which the genetic code itself has been expanded with new building blocks that allow us to probe and manipulate the structures and functions of proteins with unprecedented precision.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Adding New Chemistries to the Genetic Code
Liu, C. C., & Schultz, P. G. (2010) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.052308.105824 · Cited by 1,725
Self-citationEncoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome
Neumann, H., Wang, K., Davis, L., Garcia-Alai, M., & Chin, J. W. (2010) · Nature · doi:10.1038/nature08817 · Cited by 622
Expanding and Reprogramming the Genetic Code of Cells and Animals
Chin, J. W. (2014) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060713-035737 · Cited by 476
Protein synthesis by ribosomes with tethered subunits
Orelle, C., Carlson, E. D., Szal, T., Florin, T., Jewett, M. C., & Mankin, A. S. (2015) · Nature · doi:10.1038/nature14862 · Cited by 231
Genetic Incorporation of Unnatural Amino Acids into Proteins in Mycobacterium tuberculosis
Wang, F., Robbins, S., Guo, J., Shen, W., & Schultz, P. G. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009354 · Cited by 64
Self-citation
Cited by
Root of the Tree: The Significance, Evolution, and Origins of the Ribosome
Bowman, J. C., Petrov, A. S., Frenkel-Pinter, M., Penev, P. I., & Williams, L. D. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.9b00742 · Cited by 197
Uncovering post-translational modification-associated protein–protein interactions
Wang, S., Osgood, A. O., & Chatterjee, A. (2022) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2022.102352 · Cited by 153
Chen, Y., Jin, S., Zhang, M., Hu, Y., Wu, K.-L., Chung, A., Wang, S., Tian, Z., Wang, Y., Wolynes, P. G., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-33111-4 · Cited by 90
Selecting Better Biocatalysts by Complementing Recoded Bacteria**
Rubini, R., Jansen, S. C., Beekhuis, H., Rozeboom, H. J., & Mayer, C. (2023) · Angewandte Chemie International Edition · doi:10.1002/anie.202213942 · Cited by 15
Metadata
- Authors
- Young, D. D., & Schultz, P. G.
- Venue
- ACS Chemical Biology
- Publisher
- American Chemical Society (ACS)
- Published
- 2018-01-18
- Volume
- 13
- Issue
- 4
- Pages
- 854-870
- ISSN
- 1554-8929 (ISSN-L)
- 1554-8937
- OpenAlex
- W2783286140
- Cited by
- 345
- References
- 5
- FWCI
- 11.30
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Playing with the Molecules of Life. https://app.cochat.ai/papers/10.1021/acschembio.7b00974
- The paper
- Young, D. D., & Schultz, P. G. (2018). Playing with the Molecules of Life. ACS Chemical Biology. https://doi.org/10.1021/acschembio.7b00974
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
