The Role of Reactive Oxygen Species and Ferroptosis in Heme-Mediated Activation of Human Platelets
NaveenKumar, Somanathapura K., SharathBabu, Bidare N., Hemshekhar, Mahadevappa, Kemparaju, Kempaiah, Girish, Kesturu S., Mugesh, Govindasamy·2018·ACS Chemical Biology
Cited by (137)
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- Zinc protoporphyrin accumulation as a positive regulator of renal heme oxygenase-1 participates in the progression of chronic kidney diseaseLi-Ting Tsai, Cheng‐Tien Wu, Cong-Yun Liu, Chih‐Kang Chiang, Shing‐Hwa Liu · 2025 · Biochemical and Biophysical Research Communications
- A double-edged sword: antibody-mediated procoagulant platelets in COVID-19Sarah L. Millington‐Burgess, Matthew Thomas Harper · 2021 · Platelets
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- Receptor‐Dependent and ‐Independent Effects of Hemin on Platelet Plasma Membrane DisintegrationZoi Laspa, Anne‐Katrin Rohlfing, Ravi Hochuli, Pamela Weronika Sowa, Tatsiana Castor, Meinrad Gawaz · 2026 · The FASEB Journal
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- Hump-Nosed Pit Viper (Hypnale hypnale) Venom-Induced Irreversible Red Blood Cell Aggregation, Inhibition by Monovalent Anti-Venom and N-AcetylcysteineVaddaragudisalu D. Sandesha, Puttaswamy Naveen, Kurnegala Manikanta, Shanmuga S. Mahalingam, Kesturu Subbaiah Girish, Kempaiah Kemparaju · 2024 · Cells
- Prognostic implication of six m6A-modulated genes signature in the ferroptosis for hepatocellular carcinoma patientsYu He, Zhi-Lin Zou, Zuyong Lan, Ming Chang, Xiao Zhang, Risheng Lin, Wen Zhang, Guang-Tao Zhang, Ting Wang, Er-Bao Chen · 2025 · Clinical and Experimental Medicine (Testo stampato)
- Inhibitors of Oxytosis/Ferroptosis: A New Class of Therapeutics for Alzheimer’s DiseasePamela A Maher · 2023 · Springer eBooks
- [Research Progress of Nrf2 and Ferroptosis in Tumor Drug Resistance].Shuning Hu, Xinru Zou, Yixuan Fang, Chengrui Liu, Rui Chen, Lili Ji · 2023 · PubMed Central
- Ferroptosis in Cancer DiseaseBehrouz Hassannia, Tom Vanden Berghe · 2019 · Springer eBooks
- HD Spot: Interpretable Deep Learning Classification of Single Cell Transcript DataEric W. Prince, Todd Cameron Hankinson · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Hemin-induced platelet activation is regulated via ACKR3 chemokine surface receptor - implications for passivation of vulnerable atherosclerotic plaqueZoi Laspa, Valerie Dicenta, David Schaale, Manuel Sigle, Ravi Hochuli, Tatsiana Castor, Alp Bayrak, Tobias Harm, Karin Anne Lydia Mueller, Thanigaimalai Pillaiyar et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Evaluation of dose-dependent hematotoxic effects of celastrol on human blood cells in vitroGayathri Hemant, Kurnegala Manikanta, Somanathapura K. Naveen. Kumar, Chandrashekar Tejas, Mysuru L Sumedini, Kunthurumole S. Prashanth, Kabburahalli Sunitha, Kempaiah Kemparaju, Kesturu Subbaiah Girish · 2026 · Toxicology Letters
- Chitosan/DNA-poly(sodium-4-styrenesulfonate) microspheres for hemoadsorption of histones: Synergistic integration of charge repulsion via phase inversion and in situ crosslinkingYuehua Chen, Shujing Wang, Xu Zhou, Yu Cheng, Jiahao Liang, Shengjun Cheng, Dongmei Tong, Hongyu Xiang, Xianda Liu, Tinghang Yang et al. · 2026 · Carbohydrate Polymers
- Iron metabolism and ferroptosis in cardiovascular diseases: progress in the mechanism and pharmacological interventionYi Jiang, Jing Zhang, Liu-Ting Zeng, Yu-Lin Li, Dong-Jin Wang, Yang Li, Ling-Yun Sun, Fu-Dong Fan · 2026 · Redox Biology
- Heme induced cell death: You can run from TLR4 but you cannot hide from ROSRafael Cardoso Maciel Costa Silva · 2023 · Advances in Redox Research
- Faculty Opinions recommendation of Cytochrome P450 oxidoreductase contributes to phospholipid peroxidation in ferroptosis.Martin Vabulas · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Faculty Opinions recommendation of Cytochrome P450 oxidoreductase contributes to phospholipid peroxidation in ferroptosis.Jason M. Crawford, Natavan Dudkina · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Binding analysis of horse and bovine ferritins using beads immobilized with alpha-casein-: detection of ferritin binding or nonbinding with heme using alpha-casein-immobilized beadsRyo Hasegawa, Ayana Takahashi, Yasunaga Yoshikawa, Koichi Orino · 2023 · Research Square
- Effects of Maternal Protein Diet and Colostrum Quality on the Peripheral Blood Mononuclear Cell Transcriptome of Newborn CalvesShize Xiao, Ilke Van Hese, Zhen Liu, Karen Goossens, Martine Schroyen · 2024 · SSRN Electronic Journal
- Non-Enantioselective, Enantioselective, and Two-Dimensional Liquid Chromatography Coupled with Tandem Mass Spectrometry for the Study of Stereochemical Disposition of Oxylipins in Cgmp-Regulated Hemin-Treated PlateletsXiaoqing Fu, Cornelius Knappe, Anne‐Katrin Rohlfing, Meinrad Gawaz, Michael Laemmerhofer · 2024 · SSRN Electronic Journal
- Fluorescence ‘Turn‐on’ Receptor 2‐((E)‐(6‐(Diethylamino)‐2‐methylpyridin‐3‐ylimino) Methyl) Phenol for Nanomolar Fe (III) Detection in Lung Cancer CellsDinesh Khairnar, JunHyuk Kim, Satish Balasaheb Nimse, Pritam Torawane, Vikas Patil, Nikhil Borane, Anil Kuwar · 2025 · ChemistrySelect
- Platelet lipidome alterations in septic shock: a matched case-control studyEmma de Cartier d’Yves, Mélanie Dechamps, Jérôme Ambroise, Anik Forest, Caroline Daneault, Alessandro Campion, Valentine Robaux, Julien De Poortere, Marie Octave, Audrey Ginion et al. · 2025 · Research and Practice in Thrombosis and Haemostasis
- Hemin-Based Polymer Nanomicelles for Ferroptosis-Mediated Tumor TherapyAbu Raihan Sarkar, Anindita Chanda, Nayana Mukherjee, Mahuya Sengupta, Nikhil Ranjan Jana · 2026 · ACS Applied Bio Materials
- Heme-induced metabolic stress mediates ferroptosis response in sickle erythroblastsCaixia Xi, Mayuko Takezaki, Huidong Shi, Betty S. Pace, Xingguo Zhu · 2026 · Blood Red Cells & Iron
- HIF ‐1α/ HMOX1 ‐Mediated Ferroptosis in Macrophages Exacerbates Malaria ProgressionGuikuan Liang, J Li, Xiongyu Xie, Haiwen Yuan, Wei Xiao, Mingjie Chen, Keyu Lu, Long Xu, Li Pan, Haixia Wei et al. · 2026 · The FASEB Journal
- Non-canonical Platelet activation by oral squamous cell carcinoma extracellular vesicles through cooperative thrombin formationRui Chen, Ge Jin, Thomas M. McIntyre · 2026 · Biochemical and Biophysical Research Communications
- Indian cobra (Naja naja) venom cytotoxin fraction propels platelet apoptosis via the endocytic-lysosomal-mitochondrial axisKunthurumole S. Prashanth, Kollenahalli V. Karthik, Guthalu C. Chithrashree, Gayathri Hemant, Mysuru L Sumedini, Kesturu Subbaiah Girish, Kempaiah Kemparaju · 2026 · International Journal of Biological Macromolecules
- Synergistic modulation of cAMP and cGMP rescues hemin-induced plasma membrane fragmentationZoi Laspa, Anne‐Katrin Rohlfing, Melina Fischer, Ferdinand Kollotzek, Tatsiana Castor, Oliver Borst, Pamela Weronika Sowa, Manuel Sigle, Tobias Harm, Meinrad Gawaz · 2026 · Journal of Biological Chemistry
- A Minimal Hemin-Albumin Nanozyme with Peroxidase-like Activity Enabling Tyrosine-Crosslinked Hydrogel FormationRocío López‐Domene, Alice Delhaes, Arthur Lamouroux, Maria Haykal, Lena Léna Alembik, Thomas Daubon, Océane C. B. Martin, Sébastien Lecommandoux, Élisabeth Garanger · 2026 · ACS Applied Materials & Interfaces
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