The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Human Induced Pluripotent Stem Cells for Tumor Targeted Delivery of Gold Nanorods and Enhanced Photothermal Therapy
Abstract
How to improve effective accumulation and intratumoral distribution of plasmonic gold nanoparticles has become a great challenge for photothermal therapy of tumors. Herein, we reported a nanoplatform with photothermal therapeutic effects by fabricating Au nanorods@SiO2@CXCR4 nanoparticles and loading the prepared nanoparticles into the human induced pluripotent stem cells(AuNRs-iPS). In virtue of the prominent optical properties of Au nanorods@SiO2@CXCR4 and remarkable tumor target migration ability of iPS cells, the Au nanorods delivery mediated by iPS cells via the nanoplatform AuNRs-iPS was found to have a prolonged retention time and spatially even distribution in MGC803 tumor-bearing nude mice observed by photoacoustic tomography and two-photon luminescence. On the basis of these improvements, the nanoplatform displayed a robust migration capacity to target the tumor site and to improve photothermal therapeutic efficacy on inhibiting the growth of tumors in xenograft mice under a low laser power density. The combination of gold nanorods with human iPS cells as a theranostic platform paves an alternative road for cancer theranostics and holds great promise for clinical translation in the near future.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Klopp, A. H., Gupta, A., Spaeth, E., Andreeff, M., & Marini, F. (2011) · Stem Cells · doi:10.1002/stem.559 · Cited by 562
Cited by
Gold Nanoparticles for Photothermal Cancer Therapy
Vines, J. B., Yoon, J.-H., Ryu, N.-E., Lim, D.-J., & Park, H. (2019) · Frontiers in Chemistry · doi:10.3389/fchem.2019.00167 · Cited by 906
Nanomaterials in Targeting Cancer Stem Cells for Cancer Therapy
Qin, W., Huang, G., Chen, Z., & Zhang, Y. (2017) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00001 · Cited by 656
Recent advances in selective photothermal therapy of tumor
Zhao, L., Zhang, X., Wang, X., Guan, X., Zhang, W., & Ma, J. (2021) · Journal of Nanobiotechnology · doi:10.1186/s12951-021-01080-3 · Cited by 445
Versatile Types of Organic/Inorganic Nanohybrids: From Strategic Design to Biomedical Applications
Zhao, N., Yan, L., Zhao, X., Chen, X., Li, A., Zheng, D., Zhou, X., Dai, X., & Xu, F.-J. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00401 · Cited by 429
Cai, Y., Liang, P., Tang, Q., Yang, X., Si, W., Huang, W., Zhang, Q., & Dong, X. (2017) · ACS Nano · doi:10.1021/acsnano.6b07927 · Cited by 422
Metadata
- Authors
- Liu, Y., Yang, M., Zhang, J., Zhi, X., Li, C., Zhang, C., Pan, F., Wang, K., Yang, Y., Martinez de la Fuentea, J., & Cui, D.
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2016-01-19
- Volume
- 10
- Issue
- 2
- Pages
- 2375-2385
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W2232623525
- Cited by
- 211
- References
- 1
- FWCI
- 18.39
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
