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Cited by 420

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

The Toxicity of Mercury and Its Chemical Compounds: Molecular Mechanisms and Environmental and Human Health Implications: A Comprehensive Review

Open access
Wu, Yuan-Seng, Osman, Ahmed I., Hosny, Mohamed, Elgarahy, Ahmed M., Eltaweil, Abdelazeem S., Rooney, David W., Chen, Zhonghao, Rahim, Nur Syafiqah, Sekar, Mahendran, Gopinath, Subash C. B., Mat Rani, Nur Najihah Izzati, Batumalaie, Kalaivani, Yap, Pow-Seng·2024·ACS Omega

Abstract

Mercury is a type of hazardous and toxic pollutant that can result in detrimental effects on the environment and human health. This review is aimed at discussing the state-of-the-art progress on the recent developments on the toxicity of mercury and its chemical compounds. More than 210 recent works of literature are covered in this review. It first delineates the types (covering elemental mercury, inorganic mercury compounds, organic mercury compounds), structures, and sources of mercury. It then discusses the pharmacokinetic profile of mercury, molecular mechanisms of mercury toxicity, and clinical manifestation of acute and chronic mercury toxicity to public health. It also elucidates the mercury toxicity to the environment and human health in detail, covering ecotoxicity, neurotoxicity diseases, neurological diseases, genotoxicity and gene regulation, immunogenicity, pregnancy and reproductive system damage, cancer promotion, cardiotoxicity, pulmonary diseases, and renal disease. In order to mitigate the adverse effects of mercury, strategies to overcome mercury toxicity are recommended. Finally, some future perspectives are provided in order to advance this field of research in the future.

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Registry

Crossref · 10.1021/acsomega.3c07047

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Metadata

Authors
Wu, Y.-S., Osman, A. I., Hosny, M., Elgarahy, A. M., Eltaweil, A. S., Rooney, D. W., Chen, Z., Rahim, N. S., Sekar, M., Gopinath, S. C. B., Mat Rani, N. N. I., Batumalaie, K., & Yap, P.-S.
Venue
ACS Omega
Published
2024-01-22
Volume
9
Issue
5
Pages
5100-5126
ISSN
2470-1343 (ISSN-L)
OpenAlex
W4391090816
Cited by
420
References
2
FWCI
66.68
Type
journal article
Language
en
Open access
gold

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