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Electron-Transfer Processes of Cytochrome c at Interfaces. New Insights by Surface-Enhanced Resonance Raman Spectroscopy

Murgida, Daniel H., Hildebrandt, Peter·2004·Accounts of Chemical Research

Abstract

The heme protein cytochrome c acts as an electron carrier at the mitochondrial-membrane interface and thus exerts its function under the influence of strong electric fields. To assess possible consequences of electric fields on the redox processes of cytochrome c, the protein can be immobilized to self-assembled monolayers on electrodes and studied by surface-enhanced resonance Raman spectroscopy. Such model systems may mimic some essential features of biological interfaces including local electric field strengths. It is shown that physiologically relevant electric field strengths can effectively modulate the electron-transfer dynamics and induce conformational transitions.

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Metadata

Authors
Murgida, D. H., & Hildebrandt, P.
Venue
Accounts of Chemical Research
Published
2004-09-08
Volume
37
Issue
11
Pages
854-861
ISSN
  • 0001-4842 (ISSN-L)
  • 1520-4898
OpenAlex
W2163702232
Cited by
236
References
0
FWCI
4.15
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Electron-Transfer Processes of Cytochrome c at Interfaces. New Insights by Surface-Enhanced Resonance Raman Spectroscopy. https://app.cochat.ai/papers/10.1021/ar0400443
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Murgida, D. H., & Hildebrandt, P. (2004). Electron-Transfer Processes of Cytochrome c at Interfaces. New Insights by Surface-Enhanced Resonance Raman Spectroscopy. Accounts of Chemical Research. https://doi.org/10.1021/ar0400443

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