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Cited by 262

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

The Synthesis and Chelation Chemistry of DOTA−Peptide Conjugates

De León-Rodríguez, Luis M., Kovacs, Zoltan·2008·Bioconjugate Chemistry

Abstract

Metal complexes of DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid)-peptide conjugates are increasingly used as targeted imaging and therapeutic radiopharmaceuticals and MRI contrast agents. This review covers the bifunctional derivatives of DOTA, the solution and solid-phase synthesis of DOTA-peptide conjugates, their coordination and chelation chemistry, and the biomedical applications of various DOTA-peptide conjugate metal complexes.

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Metadata

Authors
De León-Rodríguez, L. M., & Kovacs, Z.
Venue
Bioconjugate Chemistry
Published
2007-12-12
Volume
19
Issue
2
Pages
391-402
ISSN
  • 1043-1802 (ISSN-L)
  • 1520-4812
OpenAlex
W2037725619
Cited by
262
References
1
FWCI
12.77
Type
journal article
Language
en
Open access
closed

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