Translational termination: “stop” for protein synthesis or “pause” for regulation of gene expression
Abstract
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTranslational termination: "stop" for protein synthesis or "pause" for regulation of gene expressionWarren P. Tate and Chris M. BrownCite this: Biochemistry 1992, 31, 9, 2443–2450Publication Date (Print):March 10, 1992Publication History Published online1 May 2002Published inissue 10 March 1992https://pubs.acs.org/doi/10.1021/bi00124a001https://doi.org/10.1021/bi00124a001research-articleACS PublicationsRequest reuse permissionsArticle Views218Altmetric-Citations99LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access opt…
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The translation termination signal is more than a stop codon, including the downstream +4 site (tetranucleotide stop signal).
“It has long been recognized that the translation termination signal is more than a stop codon [86,87], leading to an early proposal of tetranucleotide stop signal including the downstream +4 site [63,65,87,88].”
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- Authors
- Tate, W. P., & Brown, C. M.
- Affiliations
- University of Otago (NZ)
- Venue
- Biochemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 1992-03-10
- Volume
- 31
- Issue
- 9
- Pages
- 2443-2450
- ISSN
- 0006-2960 (ISSN-L)
- 1520-4995
- OpenAlex
- W2090583952
- Cited by
- 138
- References
- 0
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 1 · 2021: 1 · 2020: 1 · 2018: 8 · 2015: 2 · 2014: 3 · 2012: 1
- FWCI
- 5.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biochemistry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Research and Splicing
- Keywords
- translation termination, stop codon, ribosome pausing, gene expression regulation, ribosome, translation termination factor
- MeSH terms
- Base Sequence, Codon, Escherichia coli, Gene Expression Regulation, Humans, RNA, Messenger, RNA, Ribosomal, Saccharomyces cerevisiae, Protein Biosynthesis
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