Why do some organisms use a urea-methylamine mixture as osmolyte? Thermodynamic compensation of urea and trimethylamine N-oxide interactions with protein
Lin, Tiao-Yin, Timasheff, Serge N.·1994·Biochemistry
Cited by (372)
Items 201–300 of 372
- Single‐Molecule‐Level Evidence for the Osmophobic EffectDaniel Aioanei, Shanshan Lv, Isabella Tessari · 2011 · Angewandte Chemie
- Microscopic significance of hydrophobic residues in the protein-stabilizing effect of trimethylamine N-oxide (TMAO)Yanmei Yang, Yuguang Mu, Weifeng Li · 2016 · Physical Chemistry Chemical Physics
- Testing the dependence of stabilizing effect of osmolytes on the fractional increase in the accessible surface area on thermal and chemical denaturations of proteinsSafikur Rahman, Syed Ausaf Ali, Asimul Islam · 2015 · Archives of Biochemistry and Biophysics
- Protein folding and stability in the presence of osmolytesAlexander V. Fonin, Vladimir Nikolaevich Uversky, Irina М. Kuznetsova, Туроверов Константин Константинович · 2016 · BIOPHYSICS
- Chemical chaperone-mediated protein folding: stabilization of P22 tailspike folding intermediates by glycerolRajesh Mishra, Rajiv Bhat, Robert Seckler · 2007 · Biological Chemistry
- Dynamical Effects of Trimethylamine N-Oxide on Aqueous Solutions of UreaXiaojing Teng, Toshiko Ichiye · 2019 · The Journal of Physical Chemistry B
- Counteracting Effect of Charged Amino Acids Against the Destabilization of Proteins by ArginineBramhini Anumalla, Nagu Prakash Prabhu · 2019 · Applied Biochemistry and Biotechnology
- Osmolyte-Induced Collapse of a Charged MacromoleculeMrinmoy Mukherjee, Jagannath Mondal · 2019 · The Journal of Physical Chemistry B
- Influence of polar co-solutes and salt on the hydration of lipid membranesAmanuel Wolde-Kidan, Quoc Dat Pham, Alexander Schlaich, Philip Loche, Emma Sparr, Roland R. Netz, Emanuel Schneck · 2019 · Physical Chemistry Chemical Physics
- Individual and combined effects of urea and trimethylamine N-oxide (TMAO) on protein structuresZhaoqian Su, Cristiano L. Dias · 2019 · Journal of Molecular Liquids
- Effect of Sucrose on Formation of the .BETA.-Amyloid Fibrils and D-Aspartic Acids in A.BETA.1-42.Tadashi Ueda, Makiko Nagata, Akira Monji, Ichiro Yoshida, Nobutada Tashiro, Taiji Imoto · 2002 · Biological and Pharmaceutical Bulletin
- Urea and methylamines have similar effects on aldose reductase activityMaurice B. Burg, Eugenia M. Peters · 1997 · American Journal of Physiology-Renal Physiology
- Bulk Gold-Catalyzed Reactions of Isocyanides, Amines, and Amine N-OxidesErik R. Klobukowski, Robert J. Angelici, L. Keith Woo · 2012 · Organometallics
- Anomalous lateral diffusion of lipids during the fluid/gel phase transition of a lipid membraneAbhay Kumar, Snehasis Daschakraborty · 2023 · Physical Chemistry Chemical Physics
- Interactions of Trimethylamine N −Oxide and Water with c yclo -AlanylglycineKaren G. Hovagimyan, John T. C. Gerig · 2005 · The Journal of Physical Chemistry B
- Osmolyte solutions and protein foldingChar Y. Hu, Bernard Montgomery Pettitt, Joerg Roesgen · 2009 · F1000 Biology Reports
- Regulation of interrenal gland steroidogenesis in the Atlantic stingray (Dasyatis sabina)Scott Nunez, John M. Trant · 1999 · Journal of Experimental Zoology
- Collapse of a Hydrophobic Polymer in a Mixture of DenaturantsPayel Das, Zhen Xia, Ruhong Zhou · 2013 · Langmuir
- How Does a Hydrophobic Macromolecule Respond to a Mixed Osmolyte Environment?Indrajit Tah, Jagannath Mondal · 2016 · The Journal of Physical Chemistry B
- Effect of compatible and noncompatible osmolytes on the enzymatic activity and thermal stability of bovine liver catalaseHessam Sepasi Tehrani, Ali Akbar Moosavi‐Movahedi, Hedayatollah Ghourchian · 2012 · Journal of Biomolecular Structure and Dynamics
- Urea and KCl have differential effects on enzyme activities in liver and muscle of estivating versus nonestivating speciesKyra J. Cowan, Kenneth B. Storey · 2002 · Biochemistry and Cell Biology
- Effect of Temperature and Solvent on Fibrillation of Human Serum AlbuminNITIN KUMAR PANDEY, Sudeshna Ghosh, Debi Ranjan Tripathy · 2015 · Protein and Peptide Letters
- Living with urea stressLaishram Rajendrakumar Singh, Tanveer Ali Dar, Faizan Ahmad · 2009 · Journal of Biosciences
- From propensities to patterns to principles in protein foldingGeorge D. Rose · 2023 · Proteins Structure Function and Bioinformatics
- Effects of a Protecting Osmolyte on the Ion Atmosphere Surrounding DNA DuplexesJoshua M. Blose, Suzette A. Pabit, Steve P. Meisburger, Li Li, Christopher D. Jones, Lois Pollack · 2011 · Biochemistry
- Counteraction of the deleterious effects of urea on structure and stability of mammalian kidney proteins by osmolytesMohammad Aasif Dar, Wahiduzzaman, Asimul Islam · 2017 · International Journal of Biological Macromolecules
- Mechanisms of urea tolerance in urea-adapted populations ofDrosophila melanogasterRegine Etienne, Kechener Fortunat, Valerie A. Pierce · 2001 · Journal of Experimental Biology
- TMAO: Protecting proteins from feeling the heatMayank M. Boob, Shahar Sukenik, Martin Gruebele, Taras V. Pogorelov · 2023 · Biophysical Journal
- A current perspective on the compensatory effects of urea and methylamine on protein stability and functionSafikur Rahman, Marina Warepam, Laishram Rajendrakumar Singh, Tanveer Ali Dar · 2015 · Progress in Biophysics and Molecular Biology
- Osmolyte induced enhancement of expression and solubility of human dihydrofolate reductase: An in vivo studyNaira Rashid, Charu Thapliyal, Pratima Chaudhuri · 2017 · International Journal of Biological Macromolecules
- Improved Procedure for the Synthesis of Enamine N-OxidesDavid Bernier, Alexander J. Blake, Simon Woodward · 2008 · The Journal of Organic Chemistry
- The effect of aqueous solutions of trimethylamine-N-oxide on pressure induced modifications of hydrophobic interactionsRahul Sarma, Sandip Paul · 2012 · The Journal of Chemical Physics
- Interplay between conformational dynamics and substrate binding regulates enzymatic activity: a single-molecule FRET studyDavid Scheerer, Dorit Levy, Remi Casier, Inbal Riven, Hisham Mazal, Gilad Haran · 2025 · Chemical Science
- On the Molecular Mechanism of Stabilization of Proteins by Cosolvents: Role of Lifshitz Electrodynamic ForcesSrinivasan Damodaran · 2012 · Langmuir
- Can Urea and Trimethylamine-N-oxide Prevent the Pressure-Induced Phase Transition of Lipid Membrane?Archita Maiti, Snehasis Daschakraborty · 2022 · The Journal of Physical Chemistry B
- A rationale for the contrasting activity (towards globular proteins) of tert-butyl alcohol and trimethylamine N-oxideGiuseppe Graziano · 2012 · Physical Chemistry Chemical Physics
- Factor Defining the Effects of Glycine Betaine on the Thermodynamic Stability and Internal Dynamics of Horse Cytochrome cRishu Jain, Deepak Sharma, Sandeep Kumar, Rajesh Kumar · 2014 · Biochemistry
- Extreme makeover: the incredible cell membrane adaptations of extremophiles to harsh environmentsArchita Maiti, Shakkira Erimban, Snehasis Daschakraborty · 2024 · Chemical Communications
- Atomistic level understanding of the stabilization of protein Trp cage in denaturing and mixed osmolyte solutionsGargi Borgohain, Sandip Paul · 2018 · Computational and Theoretical Chemistry
- Effect of urea and low temperature on the expression and activity of flavin-containing monooxygenase in the liver and gill of rainbow trout (Oncorhynchus mykiss)B.K. Larsen, Daniel Schlenk · 2001 · Fish Physiology and Biochemistry
- Synergetic effect of polyols with tetrabutylammonium bromide and urea on the thermal stability of lysozymeS. Jain, J. C. Ahluwalia · 1997 · Thermochimica Acta
- The gut metabolite, trimethylamine N-oxide inhibits protein folding by affecting cis–trans isomerization and induces cell cycle arrestKritika Kumari, Marina Warepam, Aniket Kumar Bansal, Tanveer Ali Dar, Vladimir Nikolaevich Uversky, Laishram Rajendrakumar Singh · 2021 · Cellular and Molecular Life Sciences
- Cooperative self-association of phosphorylase kinase from rabbit skeletal muscleNatalia A. Chebotareva, Alexey V. Meremyanin, Valentina F. Makeeva, Livanova Nb, Boris I. Kurganov · 2008 · Biophysical Chemistry
- Combined Effects of Methylated Cytosine and Molecular Crowding on the Thermodynamic Stability of DNA DuplexesMitsuki Tsuruta, Yui Sugitani, Naoki Sugimoto · 2021 · International Journal of Molecular Sciences
- Investigation of Osmolyte Effects on FolM: Comparison with Other Dihydrofolate ReductasesPurva Prashant Bhojane, Michael R. Duff, Harini C. Patel · 2014 · Biochemistry
- Counteracting effects of trimethylamine N-oxide and betaine on the interactions of urea with zwitterionic glycine peptidesPannur Venkatesu, Ho-mu Lin, Ming‐Jer Lee · 2009 · Thermochimica Acta
- Interactions between the protein barnase and co-solutes studied by NMRClare R. Trevitt, D. R. Yashwanth Kumar, Nicholas J. Fowler · 2024 · Communications Chemistry
- Trimethylamine-N-oxide depletes urea in a peptide solvation shellMazin Nasralla, Harrison Laurent, Oliver L. G. Alderman, Thomas Fraser Headen, Lorna Dougan · 2024 · Proceedings of the National Academy of Sciences
- Unfoldness of the denatured state of proteins determines urea: Methylamine counteraction in terms of Gibbs free energy of stabilizationSafikur Rahman, Asimul Islam, Md. Imtaiyaz Hassan · 2019 · International Journal of Biological Macromolecules
- Characterizing osmolyte chemical class hierarchies and functional group requirements for thermal stabilization of proteinsJacob Canepa, Julie Torgerson, D.K. Kim · 2020 · Biophysical Chemistry
- Statistical geometry characterization of global structure of TMAO and TBA aqueous solutionsAlexey V. Anikeenko, Evgenii D. Kadtsyn, Nikolai N. Medvedev · 2017 · Journal of Molecular Liquids
- Cellular zwitterionic metabolite analogs simultaneously enhance reaction rate, thermostability, salt tolerance, and substrate specificity of α-glucosidase瑛介 出口, Kazuya Koumoto · 2011 · Bioorganic & Medicinal Chemistry
- Possible mechanisms of the influence of hexylresorcinol on the structure-dynamic and functional properties of lysozyme proteinYu. F. Krupyanskiǐ, E. G. Abdulnasyrov, Н. Г. Лойко · 2012 · Russian Journal of Physical Chemistry B
- A chemical chaperone induces inhomogeneous conformational changes in flexible proteinsDjemel Hamdane, Christophe Velours, David Cornu, Magali Nicaise, Murielle Lombard, Marc Fontecave · 2016 · Physical Chemistry Chemical Physics
- Interactions of Some Amino Acids with Aqueous Osmoprotectant Proline at 298.15 K: Volumetric and Calorimetric StudiesRuchika Sharma, Nand Kishore · 2006 · Journal of Solution Chemistry
- Amino acids and short peptides do not always stabilize globular proteins: A differential scanning calorimetric study on their interactions with bovine α-lactalbuminBaby Sabulal, Nand Kishore · 1997 · Journal of the Chemical Society Faraday Transactions
- Near infra-red spectra of urea with glycine betaine or trimethylamine N-oxide are additiveMichael Lever, Kelly Randall, Erwin Arno Galinski · 2001 · Biochimica et Biophysica Acta (BBA) - General Subjects
- No effect of trimethylamine N-oxide on the internal dynamics of the protein native foldMargherita Gonnelli, Giovanni Battista STRAMBINI · 2001 · Biophysical Chemistry
- Dynamical Model for the Counteracting Effects of Trimethylamine N-Oxide on Urea in Aqueous Solutions under PressureXiaojing Teng, Toshiko Ichiye · 2020 · The Journal of Physical Chemistry B
- Interactions of S-peptide analogue in aqueous urea and trimethylamine- N -oxide solutions: A molecular dynamics simulation studyRahul Sarma, Sandip Paul · 2013 · The Journal of Chemical Physics
- Hydrophilicity of the hydrophobic group: Effect of cosolvents and ionsH.N. Dilip, Debashree Chakraborty · 2019 · Journal of Molecular Liquids
- Novel Use for the Osmolyte Trimethylamine N-oxide: Retaining the Psychrophilic Characters of Cold-Adapted Protease Deseasin MCP-01 and Simultaneously Improving its ThermostabilityHailun He, Xiu‐Lan Chen, Xi‐Ying Zhang · 2009 · Marine Biotechnology
- Why does TMAO stabilize the globule state of PNIPAM?Andrea Pica, Giuseppe Graziano · 2017 · Polymer
- Effect of cosolvents in the preferential binding affinity of water in aqueous solutions of amino acids and amidesDilip.H.N., Debashree Chakraborty · 2019 · Journal of Molecular Liquids
- Hofmeister Order of Anions on Protein Stability Originates from Lifshitz–van der Waals Dispersion Interaction with the Protein PhaseLei Zhao, Srinivasan Damodaran · 2019 · Langmuir
- Structural landscape of the proline-rich domain of Sos1 nucleotide exchange factorCaleb B. McDonald, Vikas S. Bhat, Dmitry Kurouski · 2013 · Biophysical Chemistry
- Therapeutic Approaches to Delay the Onset of Alzheimer's DiseaseRaj Kumar, Hani Atamna · 2011 · Journal of Aging Research
- Counteracting Effects of TrimethylamineN-Oxide against Urea in Aqueous Solutions: Insights from Theoretical Two-Dimensional Infrared SpectroscopyRavi Malik, Amalendu Chandra · 2023 · The Journal of Physical Chemistry B
- Dimethyl sulfoxide (DMSO) is a stabilizing co-solvent for G-quadruplex DNANabeel Tariq, Takuma Kume, Lingyan Luo · 2022 · Biophysical Chemistry
- Osmolyte-Induced Macromolecular Aggregation Is Length-Scale DependentMrinmoy Mukherjee, Jagannath Mondal · 2019 · The Journal of Physical Chemistry B
- Assistance for Folding of Disease-Causing Plasma Membrane ProteinsKarina Juarez-Navarro, Víctor M. Ayala‐García, Estela Ruiz‐Baca, Iván Meneses‐Morales, Jose Luis Rios-Banuelos, Angélica López-Rodríguez · 2020 · Biomolecules
- Some notes on crystallizing fibrinogen and fibrin fragmentsRussell F. Doolittle · 2002 · Biophysical Chemistry
- Effect of nonpolar confinement on protein Trp cage conformation in aqueous osmolyte solutionsGargi Borgohain, Sandip Paul · 2017 · Journal of Molecular Liquids
- A comparative study of hydrogen bonding structure and dynamics in aqueous urea solution of amides with varying hydrophobicity: Effect of addition of trimethylamine N -oxide (TMAO)Apramita Chand, Snehasis Chowdhuri · 2017 · Journal of Molecular Liquids
- Trimethylamine N‐oxide as a media supplement for cartilage tissue engineeringGrace D. O’Connell, Jason V. Fong, Neil Dunleavy · 2012 · Journal of Orthopaedic Research®
- Salt Potentiates Methylamine Counteraction System to Offset the Deleterious Effects of Urea on Protein Stability and FunctionSafikur Rahman, Md Tabish Rehman, Laishram Rajendrakumar Singh · 2015 · PLoS ONE
- Folding/unfolding of protein Trp cage in aqueous osmolyte solutions under polar confinementGargi Borgohain, Sandip Paul · 2017 · Journal of Molecular Liquids
- Effect of osmolytes on the binding of EGR 1 transcription factor to DNADavid C. Mikles, Vikas S. Bhat, Brett J. Schuchardt, Caleb B. McDonald, Amjad Farooq · 2014 · Biopolymers
- Density variations of TMAO solutions in the kilobar range: Experiments, PC-SAFT predictions, and molecular dynamics simulationsMichael Knierbein, Christoph Held, Christoph Hölzl, Dominik Horinek, Michael Paulus, Gabriele Sadowski, Christian Sternemann, Julia Nase · 2019 · Biophysical Chemistry
- Exclusion and retention of compensatory kosmotropes by HPLC columnsMichael Lever · 1998 · Biochimica et Biophysica Acta (BBA) - General Subjects
- Osmolyte-induced protein stability changes explained by graph theoryMattia Miotto, Nina Warner, Giancarlo Ruocco · 2024 · Computational and Structural Biotechnology Journal
- Urea Stress: Myo-inositol's efficacy to counteract destabilization of TIM-β-globin complex by urea is as good as that of the methylamineWahiduzzaman, Md. Imtaiyaz Hassan, Asimul Islam, Faizan Ahmad · 2019 · International Journal of Biological Macromolecules
- Basket-type G-quadruplex with two tetrads in the presence of TMAO and urea: A molecular dynamics studyEwa Anna Oprzeska‐Zingrebe, Jens Smiatek · 2022 · Journal of Molecular Structure
- Protein-Osmolyte Interactions: Molecular InsightsFasil Ali, Usma Manzoor, Mudasser Azam, Naseem A. Ansari · 2017 · Springer eBooks
- Raman spectroscopic and quantum chemical investigation of the effects of trimethylamine N‐oxide on hydrated guanidinium and hydrogen‐bonded water networksGenevieve A. Verville, Mary Hannah Byrd, Andrew Kamischke · 2021 · Journal of Raman Spectroscopy
- The protein-stabilizing effects of TMAO in aqueous and non-aqueous conditionsHassan Monhemi, Hai Nam Hoang, Daron M. Standley, Tomoko Matsuda, Mohammad Reza Housaindokht · 2022 · Physical Chemistry Chemical Physics
- Thermodynamic properties of aqueous osmolyte solutions at high-pressure conditionsMichael Knierbein, Maximilian Venhuis, Christoph Held, Gabriele Sadowski · 2019 · Biophysical Chemistry
- Thermodynamics of the interactions of some chloro-substituted alcohols with hen egg-white lysozymeBaby Sabulal, Nand Kishore · 1996 · Journal of the Chemical Society Faraday Transactions
- 4-Chlorobutanol induces unusual reversible and irreversible thermal unfolding of ribonuclease A: thermodynamic, kinetic, and conformational characterizationRanjana Mehta, Agnita Kundu, Nand Kishore · 2004 · International Journal of Biological Macromolecules
- Preformulation Research: Assessing Protein Solution Behavior during Early DevelopmentBernardo Pérez-Ramírez, Nicholas A. Guziewicz, Robert Simler · 2010
- Interplay of protein fluctuation and associated water dynamics in osmolyte-induced stabilizationKuldeep Singh Negi, Subhajit Rana, Tanmoy Khan · 2025 · Biophysical Journal
- Effect of TMAO and betaine on the energy landscape of photosystem IJana B. Nieder, Martin Hussels, Robert Bittl, Marc Brecht · 2014 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
- Trimethylamine N-Oxide Reduces the Susceptibility of Escherichia coli to Multiple AntibioticsJiaxin Qiao, Yan Liang, Yao Wang, Morigen Morigen · 2022 · Frontiers in Microbiology
- Probing Selection Mechanism of the Most Favorable Conformation of a Dipeptide in Chaotropic and Kosmotropic SolutionGouri S. Jas, Charles Russell Middaugh, Krzysztof Kuczera · 2016 · The Journal of Physical Chemistry B
- Role of Osmolytes in AmyloidosisSheeza Khan, Zeba Mueed, Ravi Deval, Pankaj Kumar Rai, Dinesh Kumar Prajapati, Nitesh Kumar Poddar · 2019 · IntechOpen eBooks
- Intensifying aqueous two-phase extraction by adding decisive excipients for enhancement of stability and solubility of biomoleculesMaximilian Wessner, Marc Meier, Bettina Bommarius · 2021 · Chemical Engineering and Processing - Process Intensification
- Purification and characterization of a novel l-2-amino-Δ2-thiazoline-4-carboxylic acid hydrolase from Pseudomonas sp. strain ON-4a expressed in E. coliIsamu Tashima, Takashi Yoshida, Yoshihiro Asada · 2006 · Applied Microbiology and Biotechnology
- Effects of urea and trimethylamine-N-oxide on ATPase of requiem shark myofibril and its constituentsSatoshi Kanoh, Masaya Kitamura, Yuta Horie, Yuuki Kasama, Eiji Niwa · 2001 · Fisheries Science
- Influence of TMAO and Pressure on the Folding Equilibrium of TrpCageAngelina Folberth, Nico F. A. van der Vegt · 2022 · The Journal of Physical Chemistry B
- Single-molecule FRET observes opposing effects of urea and TMAO on structurally similar meso- and thermophilic riboswitch RNAsQian Hou, Surajit Chatterjee, Paul E. Lund, Krishna Chaitanya Suddala, Nils G. Walter · 2023 · Nucleic Acids Research