The DOI matches its Crossref record.
Structure of phosphate-free ribonuclease A refined at 1.26 .ANG.
Abstract
The structure of phosphate-free bovine ribonuclease A has been refined at 1.26-A resolution by a restrained least-squares procedure to a final R factor of 0.15. X-ray diffraction data were collected with an electronic position-sensitive detector. The final model consists of all atoms in the polypeptide chain including hydrogens, 188 water sites with full or partial occupancy, and a single molecule of 2-methyl-2-propanol. Thirteen side chains were modeled with two alternate conformations. Major changes to the active site include the addition of two waters in the phosphate-binding pocket, disordering of Gln-11, and tilting of the imidazole ring of His-119. The structure of the protein and of the associated solvent was extensively compared with three other high-resolution, refined structures of this enzyme.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Structural mechanism of angiogenin activation by the ribosome
(2024) · doi:10.1038/s41586-024-07508-8 · Cited by 51
Coskun, D., Chen, W., Clark, A. J., Lu, C., Harder, E. D., Wang, L., Friesner, R. A., & Miller, E. B. (2022) · Journal of Chemical Theory and Computation · doi:10.1021/acs.jctc.2c00954 · Cited by 28
Metadata
- Authors
- Wlodawer, A., Svensson, L. A., Sjoelin, L., & Gilliland, G. L.
- Venue
- Biochemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 1988-04-19
- Volume
- 27
- Issue
- 8
- Pages
- 2705-2717
- ISSN
- 0006-2960 (ISSN-L)
- 1520-4995
- OpenAlex
- W2046033652
- Cited by
- 342
- References
- 0
- FWCI
- 8.64
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Structure of phosphate-free ribonuclease A refined at 1.26 .ANG. https://app.cochat.ai/papers/10.1021/bi00408a010
- The paper
- Wlodawer, A., Svensson, L. A., Sjoelin, L., & Gilliland, G. L. (1988). Structure of phosphate-free ribonuclease A refined at 1.26 .ANG. Biochemistry. https://doi.org/10.1021/bi00408a010
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
