Action of Proteolytic Enzymes on Tropocollagen and Insoluble Collagen*

The Native and Denatured States of Soluble Collagen

Boedtker, H., & Doty, P. M. (1956) · Journal of the American Chemical Society · doi:10.1021/ja01598a024 · Cited by 332

Effects of Pepsin Treatment on the Interaction Properties of Tropocollagen Macromolecules*

Rubin, A. L., Drake, M. P., Davison, P. F., Pfahl, D., Speakman, P. T., & Schmitt, F. O. (1965) · Biochemistry · doi:10.1021/bi00878a001 · Cited by 186

Tropocollagen: Significance of Protease-Induced Alterations

Rubin, A. L., Pfahl, D., Speakman, P. T., Davidson, P. F., & Schmitt, F. O. (1963) · Science · doi:10.1126/science.139.3549.37 · Cited by 170

A Comparison between the Dimensions of Some Macromolecules Determined by Electron Microscopy and by Physical Chemical Methods

Hall, C. E., & Doty, P. M. (1958) · Journal of the American Chemical Society · doi:10.1021/ja01539a001 · Cited by 152

Subunits of the collagen molecule

Piez, K. A., Lewis, M. S., Martin, G. R., & Gross, J. (1961) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0006-3002(61)90226-8 · Cited by 136

The Introduction of Intramolecular Covalent Cross-linkages into Ichthyocol Tropocollagen with Monofunctional Aldehydes

Veis, A., & Drake, M. P. (1963) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67933-5 · Cited by 85

The Physical Characterization of Monomeric Tropocollagen*

Davison, P. F., & Drake, M. P. (1966) · Biochemistry · doi:10.1021/bi00865a040 · Cited by 70

The Unusual Links and Cross-Links of Collagen

Harding, J. J. (1965) · Advances in protein chemistry · doi:10.1016/s0065-3233(08)60389-7 · Cited by 67

The Precipitation of Collagen Fibers from Solution

Wood, G. C. (1964) · International review of connective tissue research · doi:10.1016/b978-1-4831-6751-0.50007-0 · Cited by 66

Concerning Some Special Structural Features of the Collagen Molecule

Gallop, P. M. (1964) · Biophysical Journal · doi:10.1016/s0006-3495(64)86929-0 · Cited by 57

Effects of water-extractable components from bis-GMA-based methacrylate resin on collagen from bovine tendon

Okamoto, Y., Shintani, H., Inoue, T., & Okuda, K. (1986) · Archives of Oral Biology · doi:10.1016/0003-9969(86)90092-0 · Cited by 6

The part played by the extracellular components (collagen and albumin) in the decrease in reactivity of adipose tissue in old rats

Jelínková, M., Stuchlíková, E., & Málková, H. (1969) · Experimental Gerontology · doi:10.1016/0531-5565(69)90024-2 · Cited by 6

Hypophysectomy as an effective block in cross-linking of collagen

Deyl, Z., Everitt, A. V., & Rosmus, J. (1967) · Experimental Gerontology · doi:10.1016/0531-5565(67)90022-8 · Cited by 6

INFLUENCE OF CYCLODEXTRINS ON THE PHYSICAL PROPERTIES OF COLLAGEN

Chellam, J. (2013) · International Journal of Pharma and Bio Sciences · Cited by 5

Peptide fragments released from the collagen molecule by pronase

Deyl, Z., Rosmus, J., & Adam, M. (1971) · FEBS Letters · doi:10.1016/0014-5793(71)80062-5 · Cited by 5

Solubilization of intact collagen from hamster and baboon lung

Stock, J. W., Henning, M. C., & Collins, J. F. (1981) · Analytical Biochemistry · doi:10.1016/0003-2697(81)90198-6 · Cited by 5

Interaction of platelets with collagen modified by irradiation or partial proteolysis

Jeleńska, M., Wegrzynowicz, Z., Dancewicz, A. M., & Kopeć, M. (1973) · Thrombosis Research · doi:10.1016/0049-3848(73)90079-0 · Cited by 5

Some Properties of Insoluble Bovine Corneal Collagen

Šulcová, H., Praus, R., Deyl, Z., Goldman, J. N., & Rosmus, J. (1972) · Connective Tissue Research · doi:10.3109/03008207209152051 · Cited by 5

The hexose content of the α chains of codfish skin collagen

Francois, C. J., & Glimcher, M. J. (1966) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(66)90417-x · Cited by 5

A review of marine collagens: approaches on extractions, applications, market, and future trends

Ersinger, V. F. A., Lamas, D. L., & Massa, Á. E. (2025) · Environmental Science and Pollution Research · doi:10.1007/s11356-025-36684-x · Cited by 5

The Seventh Frederick H. Verhoeff Lecture. Collagenase and collagenase inhibitors.

François, J. (1977) · Europe PMC (PubMed Central) · Cited by 4

COLLAGEN CHEMISTRY IN RELATION TO ISINGLASS AND ISINGLASS FININGS. PART II

Leach, A. A., & Barrett, J. (1967) · Journal of the Institute of Brewing · doi:10.1002/j.2050-0416.1967.tb03057.x · Cited by 4

Nonspecific collagenolytic activity: Hydrolysis of native collagen by a mold protease

Nordwig, A., & BRETSCHNEIDER, G. (1971) · Biochimica et Biophysica Acta (BBA) - Enzymology · doi:10.1016/0005-2744(71)90197-5 · Cited by 4

Intermolecular Relationship between Neutral-salt-soluble and Acid-soluble Collagen

DAVIDSON, R. J., & Cooper, D. R. (1968) · Nature · doi:10.1038/217168a0 · Cited by 4

The effect of acetylation on the stability of collagen fiber

Fujimoto, D. (1970) · Biochimica et Biophysica Acta (BBA) - Protein Structure · doi:10.1016/0005-2795(70)90057-7 · Cited by 4

Fractionation of pepsin-digested, denatured collagen

Pikkarainen, J., Lampiaho, K., & Kulonen, E. (1971) · Biochimica et Biophysica Acta (BBA) - Protein Structure · doi:10.1016/0005-2795(71)90096-1 · Cited by 4

On the presence and localization of an unknown ninhydrin positive compound in ageing collagen

Deyl, Z., & Rosmus, J. (1967) · Experimental Gerontology · doi:10.1016/0531-5565(67)90008-3 · Cited by 4

Fractionation of pepsin-digested, denatured collagen

Lampiaho, K., Niinikoski, J., Kari, A., & Kulonen, E. (1968) · Biochimica et Biophysica Acta (BBA) - Protein Structure · doi:10.1016/0005-2795(68)90066-4 · Cited by 4

The Degradation of Human Dentine Collagen by Enzymes Derived From Bacillus Subtilis

Scott, P. G., & Leaver, A. G. (1974) · Connective Tissue Research · doi:10.3109/03008207409152258 · Cited by 4

The effects of dipalmitoyl phosphatidyl choline on the precipitation of native fibrils and segment‐long‐spacing aggregates from collagen solution

McKenzie, J. C., Belton, J. C., & Klein, R. M. (1981) · Journal of Supramolecular Structure and Cellular Biochemistry · doi:10.1002/jsscb.1981.380150303 · Cited by 4

Further studies on the chromatographic separation of the collagen molecular subunits

Cooper, D. R., & Davidson, R. J. (1968) · Journal of Chromatography A · doi:10.1016/0021-9673(68)80064-0 · Cited by 4

Studies on the structure of collagen III1. On the presence of α-keto acids in collagen

Rosmus, J., & Deyl, Z. (1967) · Cellular and Molecular Life Sciences · doi:10.1007/bf02144149 · Cited by 4

THE INTRODUCTION OF SYNTHETIC CROSS‐LINKS INTO TROPOCOLLAGEN AND THEIR EFFECTS ON THE THERMAL STABILITY OF THE MOLECULE

Woodlock, A. F., & Harrap, B. S. (1969) · International Journal of Protein Research · doi:10.1111/j.1399-3011.1969.tb01630.x · Cited by 3

Chemical Modification of Collagen and the Effects on Enzyme-Binding: Mechanistic Considerations

Giacin, J. R., & Gilbert, S. G. (1977) · Advances in experimental medicine and biology · doi:10.1007/978-1-4684-3282-4_28 · Cited by 3

On the interaction between basic telopeptides and DNA

Deyl, Z., Málková, H., & Rosmus, J. (1967) · Cellular and Molecular Life Sciences · doi:10.1007/bf02154136 · Cited by 3

Optical characterization of orientation of collagen

Chang, E. P., & Chien, J. C. W. (1973) · Biopolymers · doi:10.1002/bip.1973.360121209 · Cited by 3

Immunological properties of glomerular basement membrane antigens solubilized by elastase digestion

Stuffers-Heiman, M., Tjoeng-Mutsaerts, N., Ferwerda, W., & van Es, L. A. (1980) · Journal of Immunological Methods · doi:10.1016/0022-1759(80)90120-9 · Cited by 3

The role of the telopeptide region of collagen in the platelet-collagen interaction

Chesney, C. M., Pifer, D. D., Dabbous, M. K., & Brinkley, B. (1979) · Thrombosis Research · doi:10.1016/0049-3848(79)90253-6 · Cited by 3

2.24 Hydrogels of Decellularized Matrix

White, L. J., Saldin, L. T., Keane, T. J., Cramer, M. C., Shakesheff, K. M., & Badylak, S. F. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-803581-8.09313-9 · Cited by 2

Ageing simulating changes in the telopeptide region of the collagen molecule

Rosmus, J., Vančíková, O., & Deyl, Z. (1967) · Experimental Gerontology · doi:10.1016/0531-5565(67)90019-8 · Cited by 2

A Review of the Literature: Collagen: Its Physical Characteristics and Degradation

Weissman, A. M. (1969) · Journal of Periodontology-Periodontics · doi:10.1902/jop.1969.40.10.611 · Cited by 2

Binding of betamethasone and dexamethasone by collagen

Kanfer, I. (1977) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.1977.tb11323.x · Cited by 2

Increased lability of lung collagen crosslinks

Richmond, V. L. (1980) · Analytical Biochemistry · doi:10.1016/0003-2697(80)90075-5 · Cited by 2

PLATELET-COLLAGEN INTERACTION AND MICROVESICULATION

Siljander, P. R. M. (2000) · Työväentutkimus Vuosikirja · Cited by 2

Aging of connective tissue. Age dependency of collagen depolymerization by ionizing radiation

Svojtková, E., Deyl, Z., & Adam, M. (1973) · Experimental Gerontology · doi:10.1016/0531-5565(73)90006-5 · Cited by 1

Mineralization of nanomaterials for bone tissue engineering

Marelli, B., Ghezzi, C. E., & Nazhat, S. N. (2013) · Elsevier eBooks · doi:10.1533/9780857097231.3.387 · Cited by 1

Contamination of Acid‐Soluble Collagen with Nitrogenous Material from the Dialysis Tubing

Crevasse, G. A., & PEARSON, A. M. (1969) · Journal of Food Science · doi:10.1111/j.1365-2621.1969.tb14360.x · Cited by 1

Studies on the structure of collagen IV. A.C-terminal sequence from the pronase treated collagen

Bump, S., Deyl, Z., & Rosmus, J. (1967) · Cellular and Molecular Life Sciences · doi:10.1007/bf02137940 · Cited by 1

Healing of Biodegradable Vascular Prosthesis. Incorporation of3H-Valine Into Proteins in the Subendothelial Scar and Host Intima-Media of Rat Aorta

MOCZAR, M., Bessou, J.-P., & Loisance, D. Y. (1983) · Connective Tissue Research · doi:10.3109/03008208309005609 · Cited by 1

Purification, Partitioning and uses of fish pepsin for collagen extraction and protein hydrolysate production

Nalinanon, S. (2010) · PSU Knowledge Bank (Prince of Songkla University) · Cited by 1

Design of Collagen-mimetic peptides

Kaur, P. (2017) · CUNY Academic Works (City University of New York) · Cited by 1

An Electrical Birefringence Study of the Contribution of Permanent and Induced Dipole Moments to Acid-Soluble Collagen Polarization

Bernengo, J. C., Roux, B., & Herbage, D. (1979) · Springer eBooks · doi:10.1007/978-1-4684-3497-2_24 · Cited by 1

Development of edible films from gelatin extracted from Argentine shortfin squid «Illex Argentinus» with the use of an enzyme (pepsin) aided process

Waheed, H. (2017) · eScholarship@McGill (McGill) · doi:10.82308/7978 · Cited by 1

Corneal Collagenases and their Inhibition

François, J., & Cambie, E. (1976) · Documenta ophthalmologica. Proceedings series · doi:10.1007/978-94-010-1569-1_3

Novel Biofabrication Technologies to Recapitulate In Vivo Geometries in Collagen Hydrogels

Rodriguez-Rivera, V. (2014) · Scholar Commons (University of South Carolina)

The collagenolytic action of the proteolytic complex of streptomyces griseus on synthetic substrates

Rassulin, Y. A., & Шибнев, В. А. (1970) · Russian Chemical Bulletin · doi:10.1007/bf00861504

The absence of α-keto acids in polymeric collagen

Ayad, S., STEVEN, F. S., & Jackson, D. S. (1969) · Biochimica et Biophysica Acta (BBA) - Protein Structure · doi:10.1016/0005-2795(69)90079-8

The extraction of tropocollagen and proteoglycans from bovine eyes and investigation of their recombination using a new method to quantify fibrillogenesis

Sama, B. A. (2011) · Digital Repository Service (Northeastern University) · doi:10.17760/d20000956

Diffuse Obstructive Pulmonary Syndromes ENZYME DIGESTION

Martin, C. J., & Sugihara, T. T. (1973)

Segment-long-spacing aggregate from pepsin-solubilized bone collagen.

Kuboki, Y., Sasaki, S., SAITO, J., Ono, T., & Kawanishi, Y. (1973) · PubMed

Spontane Uterusperforation bei Endomyometritis puerperalis durch erh�hten Kollagenabbau

Hertel, H., & Schmitt, W. (1968) · Archives of Gynecology and Obstetrics · doi:10.1007/bf00668074

On the localization of tryptophane in the α3 chain of collagen

Deyl, Z., Rosmus, J., & Málková, H. (1967) · Cellular and Molecular Life Sciences · doi:10.1007/bf02136397

Studies on the inhibition of experimental liver fibrosis

Tsujii, T., Fukuhara, M., Fukuda, S., Matsui, T., Matsuoka, Y., Tamura, M., Morita, T., Kimura, K., & MORIYA, W. (1975) · Gastroenterologia Japonica · doi:10.1007/bf02776655

Inorganic–Organic Hybrids: Mimicking Native Bone

Park, H., Rezabeigi, E., & Nazhat, S. N. (2021) · Royal Society of Chemistry eBooks · doi:10.1039/9781788019828-00134

Collagen-Derived Membrane: Corneal Implantation

Dunn, M. W., Nishihara, T., Stenzel, K. H., Branwood, A. W., & Rubin, A. L. (1967) · Springer eBooks · doi:10.1007/978-1-4615-6555-0_15

Enhanced Recovery of Functional Collagen from Fish Processing Waste Via Ultrasound-Assisted Pretreatment: Process Optimization, Structural Analysis, and Cytocompatibility Study

Faralizadeh, S., Rahimabadi, E. Z., Bahrami, S. H., & hasannia, S. (2025) · Waste and Biomass Valorization · doi:10.1007/s12649-025-03438-2

The effects of proteases on the soluble and insoluble collagens and the structures of insoluble collagen fiber

Nishihara, T. (1962) · Cited by 12

Studies on the Structure of Collagen Utilizing a Collagenolytic Enzyme from Tadpole*

Kang, A. H., Nagai, Y., Piez, K. A., & Gross, J. (1966) · Biochemistry · doi:10.1021/bi00866a016 · Cited by 166

Action of Trypsin on the Properties of Collagen1

Page, R. O., & Page, A. W. (1930) · Industrial & Engineering Chemistry · doi:10.1021/ie50245a032 · Cited by 1

Effects of Pepsin Treatment on the Interaction Properties of Tropocollagen Macromolecules*

Rubin, A. L., Drake, M. P., Davison, P. F., Pfahl, D., Speakman, P. T., & Schmitt, F. O. (1965) · Biochemistry · doi:10.1021/bi00878a001 · Cited by 186

Some Properties of the Products of Reaction of Tadpole Collagenase with Collagen*

Sakai, T., & Gross, J. (1967) · Biochemistry · doi:10.1021/bi00854a021 · Cited by 246