Glycogen Synthase Kinase 3β Phosphorylates Alzheimer's Disease-Specific Ser396 of Microtubule-Associated Protein Tau by a Sequential Mechanism

Li, Tong, Paudel, Hemant K.·2006·Biochemistry

Cited by (141)

Items 101–141 of 141

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  2. Technical considerations in detection of HERV-K in amyotrophic lateral sclerosis: selection of controls and the perils of qPCR
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  3. Specific phosphorylation of microtubule-associated protein 2c by extracellular signal–regulated kinase reduces interactions at its Pro-rich regions
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  4. DpdtpA, A Multi-metal Ion Chelator, Attenuates Tau Phosphorylation and Microglial Inflammatory Response via Regulating the PI3K/AKT/GSK-3β Signal Pathways
    Lu Wang, Yingjuan Wei, Zhenzhou Sun, Lin‐Hua Jiang, Yaling Yin, Panpan Zheng, Yun Fu, Hongwei Wang, Changzheng Li, Jian‐Zhi Wang · 2023 · Neuroscience
  5. FTDP-17 missense mutations site-specifically inhibit as well as promote dephosphorylation of microtubule-associated protein tau by protein phosphatases of HEK-293 cell extract
    Dong Cho Han, Hemant K. Paudel · 2008 · Neurochemistry International
  6. APOE3 Christchurch modulates tau phosphorylation and β-catenin/Wnt/Cadherin signaling in induced pluripotent stem cell-derived cerebral organoids from Alzheimer’s cases
    Randall C. Mazzarino, Paula Andrea Perez-Corredor, Timothy E. Vanderleest, Guido N. Vacano, Justin S. Sanchez, Nelson David Villalba‐Moreno, S Krausemann, MA Mendivil-Perez, David Fernando Aguillon, Marlene Jiménez-Del-Río et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  7. CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions
    Emmy Li, Camila Benitez, Steven C. Boggess, Mark Koontz, Indigo V.L. Rose, Delsy Martinez, Nina M. Dräger, Olivia M. Teter, Avi J. Samelson, Na’im Pierce et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  8. Long-term depression-related tau phosphorylation is enhanced by methylene blue in healthy rat hippocampus
    Cem Süer, N. Yıldız Demircan, Özlem Barutçu, Burak Tan, Nurcan Dursun · 2021 · Pharmacological Reports
  9. High-Fat Diet-Induced Diabetic Conditions Exacerbate Cognitive Impairment in a Mouse Model of Alzheimer's Disease Via a Specific Tau Phosphorylation Pattern
    Yuki Ito, Shuko Takeda, Tsuneo Nakajima, A. Oyama, Haruo Takeshita, Kazumasa Miki, Yoichi Takami, Yasushi Takeya, Munehisa Shimamura, Hiromi Rakugi et al. · 2023 · The Journal of Prevention of Alzheimer s Disease
  10. Molecular Pathways in Alzheimer’s Disease and Cognitive Function
    Xu Chen, Meredith C. Reichert, Li Gan · 2016 · Elsevier eBooks
  11. Tau hyperphosphorylation and axonal damage induced by N,N‐diethyldithiocarbamate (DEDTC) treatment along late postnatal development is followed by a rescue during adulthood
    Juana Utrera, Fèlix Junyent, Luísa de Lemos, Mercè Pallàs, Antoni Camins, Rafael Romero, Carme Auladell · 2009 · Journal of Neuroscience Research
  12. The Effect of the Tau Protein on D. melanogaster Lifespan Depends on GSK3 Expression and Sex
    Ekaterina R. Veselkina, Mikhail V. Trostnikov, Natalia V. Roshina, ELENA G. PASYUKOVA · 2023 · International Journal of Molecular Sciences
  13. Mangiferin Alleviates Formaldehyde‐Induced Tau Hyperphosphorylation and Cognitive Impairment in Mice via the PI3K/AKT/GSK3β Pathway: Insights From Network Pharmacology and Experimental Validation
    Na Wang, Ziteng Sun, Fan Chen, Xinyan Tian, Juan Li, Xiaping He · 2026 · The FASEB Journal
  14. Unique Pathology in the Locus Coeruleus of Individuals with Down Syndrome
    Hannah Saternos, Eric Daniel Hamlett, Samuel J. Guzman, Elizabeth Head, Ann‐Charlotte Granholm, Aurélie Ledreux · 2024 · Journal of Alzheimer s Disease
  15. Drug Discovery from Medicinal Plants against Alzheimer's Disease
    Mona M. Marzouk, Mai Mohammed Farid, Nesrine Mahmoud Hegazi, Shahira M. Ezzat · 2023 · Wiley eBooks
  16. Accessing intractable, phosphorylated intrinsically disordered proteins via a protease‐cleavable inclusion body tag
    Cat Hoang Vesely, Stanislau Stanisheuski, Edward Lien, Patrick N. Reardon, Peter J. Chung, Ryan A. Mehl, Richard B. Cooley · 2026 · Protein Science
  17. Generation of induced pluripotent stem cells with high efficiency from human embryonic renal cortical cells.
    Ling Yao, Ruifang Chen, Pu Wang, Qi Zhang, Hailiang Tang, Huaping Sun · 2016 · PubMed Central
  18. Tau Phosphorylation and Amyloid-β Deposition in the Presence of Formaldehyde
    Jing Lü, Rongqiao He · 2017 · Springer eBooks
  19. Therapeutic targeting of glycogen synthase kinase-3: Strategy to address neurodegenerative diseases
    Saba Noor, Ali Raza, Md. Imtaiyaz Hassan · 2022 · Elsevier eBooks
  20. Distinct Hippocampal Expression Profiles of lncRNAs in Obese Type 2 Diabetes Mice Exhibiting Cognitive Impairment
    Qianqian Xu, Lihui Wang, Qiong Song, Shuai Chen, Kechen Du, Xiahong Teng, Chunlin Zou · 2024 · NeuroMolecular Medicine
  21. SARS-CoV-2 infection leads to Tau pathological signature in neurons
    Cristina Di Primio, Paola Quaranta, Marianna Mignanelli, Giacomo Siano, Matteo Bimbati, Carmen Rita Piazza, Pietro Giorgio Spezia, Paola Perrera, Fulvio Basolo, Anello Marcello Poma et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  22. Non‐amyloid Approaches To Alzheimer's Disease
    Lone Veng, Mary J. Savage, James C. Barrow, Celina Zerbinatti · 2010 · Wiley eBooks
  23. Molecular Mechanisms of Tau Protein Aggregation Inhibition
    Elias Akoury · 2013
  24. Regulation by Glycogen Synthase Kinase-3 Beta of CBP transcriptional coactivator involved in insulin-dependent glucagon gene transcription
    Andrei Matsiulka · 2007
  25. Using TUDCA to treat Alzheimer's disease after pathology onset in APP/PS1 mice
    Pedro Dionísio · 2014 · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
  26. Using TUDCA to treat Alzheimer's disease after pathology onset in APP/PS1 mice
    Faculdade De Farmácia · 2014
  27. Relationship of Adult Neurogenesis with Tau Phosphorylation and GSK-3b Activity in Subventricular Zone
    Xiao-Ping HongCai-Xia, Peng-Wei Wei · 2011
  28. Methylmercury and Cellular Signal Transduction Systems
    Masatake Fujimura, Fusako Usuki · 2022 · Springer eBooks
  29. Unprecedented prospects as forthcoming drug targets: New boulevard in the cure and treatment of neurodegenerative disorders
    Dipanjan Karati, Swarupananda Mukherjee, Nandita Batabyal · 2024 · Elsevier eBooks
  30. Amyloid β Deposition, Tau Phosphorylation, ApoE4 Dysfunction, and Formaldehyde
    Jing Lü, Rongqiao He · 2025 · Springer eBooks
  31. APOE4-APP interactions exert early influences on cerebrovascular structure and function: implications for Alzheimer’s disease
    Lanboling Guo, Jessica Ruth Gaunt, Calvin Chee Hoe Cheah, Albert I. Chen, Stephanie Claudine, Gavin Stewart Dawe, Eyleen Lay Keow Goh, Sok-Hong Kho, Pawan Kumar, Grace G. Y. Lim et al. · 2025 · Frontiers in Neuroscience
  32. Amyloid-β and phosphorylated-tau accumulation in retrosplenial cortex of young Alzheimer's disease model: Impact on network activity
    Carlos A García-Carlos, Anahí Salas-Gallardo, Perla González-Pereyra, Gustavo Basurto-Islas, George Perry, S. Mondragón-Rodríguez · 2026 · Journal of Alzheimer's Disease
  33. Tau nucléaire : un acteur clé dans le stress neuronal
    Audrey Sultan · 2010 · theses.fr (ABES)
  34. Prévention du phénomène de nucléation et de la propagation des tauopathies par immunothérapie passive utilisant un anticorps ciblant une région centrale de la protéine tau
    Marie Albert · 2018 · theses.fr (ABES)
  35. Neurotoxicité précoce et mécanismes de neuroprotection dans des modèles poisson‐zèbre de tauopathies
    Clément Barbereau · 2020 · theses.fr (ABES)
  36. Tau pSer396 and pSer404 Define Distinct Epitope Regions Linked to Different Antibody Functions
    Ruimin Pan, Erin E. Congdon, Jessica E. Chukwu, Christina C. Luo, Einar M. Sigurdsson, Xiang‐Peng Kong · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  37. Phosphoproteomics identifies Rho-kinase-associated phospho-signaling and autophagy-associated alterations in the medial prefrontal cortex of a schizophrenia-related mouse model
    Wenjun Zhu, Rinako Tanaka, Tetsuo Matsuzaki, Tsuyoshi Nakai, Taku Nagai, Toshitaka Nabeshima, Kozo Kaibuchi, Norio Ozaki, Hiroaki Ikesue, Hiroyuki Mizoguchi et al. · 2026 · Pharmacological Research
  38. The protein kinase B pathway as therapeutic target in neurodegenerative diseases: mechanisms and implications
    Rosina Sánchez-Thomas, Sandra Monserrat Bautista-Perez, Ricardo A. Santana-Martínez, Carlos Alfredo Silva‐Islas, Alejandra Figueroa, Diana Barrera‐Oviedo, Perla D. Maldonado · 2026 · Elsevier eBooks
  39. The Tau-mitochondria connection and its impact on cellular energy metabolism in Alzheimer’s disease
    Abhay Kumar Singh, Supraja M.R., Amal P.S., Senthilkumar Krishnamoorthi, Ashok Iyaswamy, Siva Sundara Kumar Durairajan · 2026 · International review of neurobiology
  40. BindingDB Entry 50033570: Switching reversibility to irreversibility in glycogen synthase kinase 3 inhibitors: clues for specific design of new compounds.
    BindingDB · 2012 · UC San Diego
  41. APH-1A and CDK5 Expression Correlates with Tau Hyperphosphorylation and Its Attenuation by Brahmi and Donep-M in STZ induced Alzheimer’s Disease Model
    Umesh Prasad Sah Hathi, Abhishek Kumar, Arora Jyotsna, Suneel Kateriya · 2026 · Research Square