Molecular Dissection of the Interaction between Amyloid Precursor Protein and Its Neuronal Trafficking Receptor SorLA/LR11

Andersen, Olav M., Schmidt, Vanessa, Spoelgen, Robert, Gliemann, Jørgen, Behlke, Joachim, Galatis, Denise, McKinstry, William J., Parker, Michael W. +4 more·2006·Biochemistry
DOI 10.1021/bi052120v

Cited by (178)

Items 101–178 of 178

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  2. Phosphorylation and Glycosylation of Amyloid-β Protein Precursor: The Relationship to Trafficking and Cleavage in Alzheimer’s Disease
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  3. Computational method for calculating fluorescence intensities within three-dimensional structures in cells
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  4. The SORL1 polymorphism rs985421 may confer the risk for amnestic mild cognitive impairment and Alzheimer's disease in the Han Chinese population
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  5. Investigating the Endo-Lysosomal System in Major Neurocognitive Disorders Due to Alzheimer’s Disease, Frontotemporal Lobar Degeneration and Lewy Body Disease: Evidence for SORL1 as a Cross-Disease Gene
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  6. The paradigm of amyloid precursor protein in amyotrophic lateral sclerosis: The potential role of the 682 YENPTY 687 motif
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  7. SorLA Deficiency Dissects Amyloid Pathology from Tau and Cholinergic Neurodegeneration in a Mouse Model of Alzheimer's Disease
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  8. Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11
    Robert Spoelgen, Kenneth W. Adams, M. Koker, A.V. Thomas, Olav M. Andersen, Penelope J. Hallett, Kathryn K. Bercury, Daniel Joyner, Meihua Deng, William H. Stoothoff et al. · 2008 · Neuroscience
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  11. SORL1 Gene is Associated with the Conversion from Mild Cognitive Impairment to Alzheimer’s Disease
    Paola Piscopo, Giuseppe Tosto, Chiara Belli, Giuseppina Talarico, Daniela Galimberti, Marina Gasparini, Marco Canevelli, Anna Poleggi, Alessio Crestini, Diego Albani et al. · 2015 · Journal of Alzheimer s Disease
  12. Mutations in SORL1 and MTHFDL1 possibly contribute to the development of Alzheimer’s disease in a multigenerational Colombian Family
    J Moreno, Andrés Villegas Lanau, Lucía Madrigal, Ana Yulied Baena Pineda, Juan Velez Hernandez, Omer Campo, Alejandro Soto-Ospina, Pedronel Araque Marín, Lavanya Rishishwar, Emily T. Norris et al. · 2022 · PLoS ONE
  13. Amine oxidase activity of β-amyloid precursor protein modulates systemic and local catecholamine levels
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  14. Multi-compartmental modeling of SORLA’s influence on amyloidogenic processing in Alzheimer’s disease
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  15. SORLA regulates calpain‐dependent degradation of synapsin
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  16. Amyloidosis causes downregulation of SorLA, SorCS1 and SorCS3 expression in mice
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  17. Retromer Regulates Postendocytic Sorting of β‐Secretase in Polarized Madin–Darby Canine Kidney Cells
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  18. Mutants of Metal Binding Site M1 in APP E2 Show Metal Specific Differences in Binding of Heparin but Not of sorLA
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  19. Effect of Alzheimer's Disease Risk Variant rs3824968 at SORL1 on Regional Gray Matter Volume and Age-Related Interaction in Adult Lifespan
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  20. Neuronal LR11 Expression Does Not Differentiate between Clinically-Defined Alzheimer's Disease and Control Brains
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  21. Endosomal trafficking is required for glycosylation and normal maturation of the Alzheimer’s-associated protein sorLA
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  23. Apolipoprotein E receptor pathways in Alzheimer disease
    Vanessa Schmidt, Anne-Sophie Carlo, Thomas E. Willnow · 2014 · WIREs Systems Biology and Medicine
  24. Bacterial expression, purification, and model membrane reconstitution of the transmembrane and cytoplasmic domains of the human APP binding protein LR11/SorLA for NMR studies
    Xinsheng Wang, Richard L. Gill, Qin Zhu, Fang Tian · 2011 · Protein Expression and Purification
  25. Wild Type and Tangier Disease ABCA1 Mutants Modulate Cellular Amyloid-β Production Independent of Cholesterol Efflux Activity
    Woojin Scott Kim, Andrew Francis Hill, Michael L. Fitzgerald, Mason Wright Freeman, Genevieve M. Evin, Brett Garner · 2011 · Journal of Alzheimer s Disease
  26. The Structure of MESD45–184 Brings Light into the Mechanism of LDLR Family Folding
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  29. SorLA in astrocytes regulates blood-brain barrier integrity
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  30. An exploratory study of the association between SORL1 polymorphisms and sporadic Alzheimer’s disease in the Han Chinese population
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  34. Crystallization and preliminary crystallographic analysis of human LR11 Vps10p domain
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  35. The Genetic Basis of Alzheimer’s Disease
    Basavaraj V. Hooli, Rudolph E. Tanzi · 2016 · Elsevier eBooks
  36. The adaptor protein PICK1 targets the sorting receptor SorLA
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  37. A Particular SORL1 Micro-haplotype May Prevent Severe Liver Disease in a French Cohort of Alpha 1-Antitrypsin-deficient Children
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  39. Downregulation of SNX27 expression does not exacerbate amyloidogenesis in the APP/PS1 Alzheimer's disease mouse model
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  40. Neuronal aging potentiates beta-amyloid generation via amyloid precursor protein endocytosis
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  41. Genetic architecture of RNA editing regulation in Alzheimer’s disease across diverse ancestral populations
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  43. Familial Alzheimer's disease mutation identifies novel role of SORLA in release of neurotrophic exosomes
    Kristian Juul‐Madsen, Ina‐Maria Rudolph, Jemila P. Gomes, Katrina Meyer, Peter Lund Ovesen, Malgorzata Gorniak‐Walas, Marianna Kokoli, Narasimha Swamy Telugu, Malthe von Tangen Sivertsen, Fabia Febbraro et al. · 2025 · Alzheimer s & Dementia
  44. Identification of two pathogenic mutations in SORL1 in early-onset Alzheimer’s disease
    Guozhen Qiu, Feiqi Zhu, Chunyan Xu · 2021 · Journal of Clinical Neuroscience
  45. MiR-7684-5p leads to surgery-induced cognitive decline in mice probably through the downregulation of SorLA.
    Chang-Wei Wei, Shan-Shan Zou, Ting L. Luo, Ya-Nan Hao, Xiaobin Zhou, Wenzhen Shen, Anshi Wu · 2017 · PubMed Central
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  49. Associations of sorLA/SORL1 with Alzheimer's disease
    Olav M. Andersen, Ishita Guha Thakurta · 2015 · Receptors & Clinical Investigation
  50. A membrane proximal helix in the cytosolic domain of the human APP interacting protein LR11/SorLA deforms liposomes
    Richard L. Gill, Xinsheng Wang, Fang Tian · 2014 · Biochimica et Biophysica Acta (BBA) - Biomembranes
  51. Amyloid Precursor Protein
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  57. Role of the 39-kDa receptor-associated protein (RAP) in Alzheimer's disease
    Hoang, T · 2012 · UTAS Research Repository
  58. Regulation of Transport and Processing of Amyloid Precursor Protein by the Sorting Receptor SORLA
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  59. SORL1 adds another piece to the complex puzzle of Alzheimer disease genetics
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  60. Nucleic Acid-Based Risk Factors and Biomarkers: A Future Perspective on their Use and Development in Alzheimer’s Disease
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  61. LossofLR11/SORLAEnhancesEarlyPathologyinaMouse ModelofAmyloidosis:EvidenceforaProximalRolein Alzheimer'sDisease
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  62. Featured Article SORLA regulates calpain-dependent degradation of synapsin
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  67. Additional file 1 of Brain transcriptome analysis reveals subtle effects on mitochondrial function and iron homeostasis of mutations in the SORL1 gene implicated in early onset familial Alzheimer’s disease
    Karissa Barthelson, Stephen Pederson, Morgan Newman, Michael T. Lardelli · 2020 · Figshare
  68. Additional file 9 of Brain transcriptome analysis reveals subtle effects on mitochondrial function and iron homeostasis of mutations in the SORL1 gene implicated in early onset familial Alzheimer’s disease
    Karissa Barthelson, Stephen Pederson, Morgan Newman, Michael T. Lardelli · 2020 · Figshare
  69. Additional file 2 of Brain transcriptome analysis reveals subtle effects on mitochondrial function and iron homeostasis of mutations in the SORL1 gene implicated in early onset familial Alzheimer’s disease
    Karissa Barthelson, Stephen Pederson, Morgan Newman, Michael T. Lardelli · 2020 · Figshare
  70. Additional file 10 of Brain transcriptome analysis reveals subtle effects on mitochondrial function and iron homeostasis of mutations in the SORL1 gene implicated in early onset familial Alzheimer’s disease
    Karissa Barthelson, Stephen Pederson, Morgan Newman, Michael T. Lardelli · 2020 · Figshare
  71. Additional file 4 of Brain transcriptome analysis reveals subtle effects on mitochondrial function and iron homeostasis of mutations in the SORL1 gene implicated in early onset familial Alzheimer’s disease
    Karissa Barthelson, Stephen Pederson, Morgan Newman, Michael T. Lardelli · 2020 · Figshare
  72. Additional file 3 of Brain transcriptome analysis reveals subtle effects on mitochondrial function and iron homeostasis of mutations in the SORL1 gene implicated in early onset familial Alzheimer’s disease
    Karissa Barthelson, Stephen Pederson, Morgan Newman, Michael T. Lardelli · 2020 · Figshare
  73. Additional file 8 of Brain transcriptome analysis reveals subtle effects on mitochondrial function and iron homeostasis of mutations in the SORL1 gene implicated in early onset familial Alzheimer’s disease
    Karissa Barthelson, Stephen Pederson, Morgan Newman, Michael T. Lardelli · 2020 · Figshare
  74. Additional file 6 of Brain transcriptome analysis reveals subtle effects on mitochondrial function and iron homeostasis of mutations in the SORL1 gene implicated in early onset familial Alzheimer’s disease
    Karissa Barthelson, Stephen Pederson, Morgan Newman, Michael T. Lardelli · 2020 · Figshare
  75. Additional file 7 of Brain transcriptome analysis reveals subtle effects on mitochondrial function and iron homeostasis of mutations in the SORL1 gene implicated in early onset familial Alzheimer’s disease
    Karissa Barthelson, Stephen Pederson, Morgan Newman, Michael T. Lardelli · 2020 · Figshare
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  78. Alzheimer's disease risk single nucleotide polymorphism rs11218343 is linked to functional expression of SORL1 in microglia
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