On the Seeding and Oligomerization of pGlu-Amyloid Peptides (in vitro)

Schilling, Stephan, Lauber, Thomas, Schaupp, Michael, Manhart, Susanne, Scheel, Eike, Böhm, Gerald, Demuth, Hans-Ulrich·2006·Biochemistry
DOI 10.1021/bi0612667

Cited by (258)

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  5. Prevention of Amyloid-β Fibril Formation Using Antibodies Against the C-terminal Region of Amyloid-β1-40 and Amyloid-β1-42
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  6. Lessons from a Rare Familial Dementia: Amyloid and Beyond
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  8. Synthesis and Evaluation of a Novel PET Radioligand for Imaging Glutaminyl Cyclase Activity as a Biomarker for Detecting Alzheimer’s Disease
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  9. Postmortem Neocortical 3H-PiB Binding and Levels of Unmodified and Pyroglutamate Aβ in Down Syndrome and Sporadic Alzheimer’s Disease
    Violetta N. Pivtoraiko, Tamara Racic, Eric E. Abrahamson, Victor L. Villemagne, Benjamin L. Handen, Ira T. Lott, Elizabeth Head, Miloš D. Ikonomović · 2021 · Frontiers in Aging Neuroscience
  10. The Small Molecule GAL-201 Efficiently Detoxifies Soluble Amyloid β Oligomers: New Approach towards Oral Disease-Modifying Treatment of Alzheimer’s Disease
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  11. A commonly used Drosophila model of Alzheimer's disease generates an aberrant species of amyloid‐β with an additional N‐terminal glutamine residue
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    Tetsuya Suhara, Makoto Higuchi, Michie Miyoshi · 2008 · The Tohoku Journal of Experimental Medicine
  13. Landscape of Protein Post-Translational Modifications in Age-Related Neurodegenerative Disorders: Implications in Protein Aggregation, Altered Cellular Processes, and Therapeutics
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  14. A Screen of Plant-Based Natural Products Revealed That Quercetin Prevents Pyroglutamylated Amyloid-β (Aβ3(pE)-42) Uptake in Astrocytes As Well As Resulting Astrogliosis and Synaptic Dysfunction
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  15. The Influence of Coordination Mode on the Redox Properties of Copper Complexes with Aβ(3‐16) and Its Pyroglutamate Counterpart pAβ(3‐16)
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  16. How Single Site Mutations Can Help Understanding Structure Formation of Amyloid β1−40
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  17. PET Applications in Animal Models of Neurodegenerative and Neuroinflammatory Disorders
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  18. An Overview of Glutaminyl Cyclase as a Promising Drug Target for Alzheimer’s Disease
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  19. Immunotherapy Against N-Truncated Amyloid-β Oligomers
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  23. Purification of recombinant Aβ(1‐42) and pGlu‐Aβ(3‐42) using preparative SDS‐PAGE
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  24. Comparative properties of Aβ1–42, Aβ11–42, and [Pyr11]Aβ11–42 generated from O-acyl isopeptides
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  25. Energy-dependent transport at dural lymphatic vessels is necessary for Aβ brain clearance in Alzheimer’s disease
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  26. Metal Ion Binding to Human Glutaminyl Cyclase: A Structural Perspective
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  27. Pyroglutamylation modulates electronic properties and the conformational ensemble of the amyloid β‐peptide
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  28. Structure and Toxicity of the Prefibrillar Aggregation States of Beta Peptides in Alzheimer’s Disease
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  29. Immunotherapeutics for Neurological Disorders
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  30. How very small changes in the peptide sequence of β-amyloids influence their redox properties. Electrochemical studies of Aβ(11-16) and pAβ(11-16) in two different electrolytes.
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  31. Die Amyloidablagerung in einem Mausmodell der Alzheimer Demenz und die Modulation der β-Amyloid-Peptidentstehung durch membranverankerte Inhibitoren
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  32. Amyloid imaging in Alzheimer´s disease and mild cognitive impairment by Positron Emission Tomography
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  33. Production et catabolisme des peptides amyloïdes dans la maladie d’Alzheimer
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  34. Paradigmenwechsel bei der Alzheimer-Krankheit: Intrazelluläre Aggregation von Amyloid-beta verursacht den Zellverlust unabhängig von extrazellulären Plaques
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  35. IMMUNOTHERAPY IN COMBINATION WITH BEHAVIORAL ENRICHMENT IN A CANINE MODEL OF AGING
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  36. PATHOGENIC ROLE OF MICROGLIA-DERIVED MICROVESICLES IN NEURODEGENERATION
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  37. Modeling Peptide-binding Interactions and Polymer-binding Interactions and their Role in Mass Spectrometry
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  38. Hereditary forms of cerebrovascular amyloidosis
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  39. Biophysical Analysis of the Structure and Aggregation of Amyloid beta Peptide
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  41. N-truncated Aβ4-x peptides in Alzheimer's disease: generation, degradation, and relationship with neuropathological hallmarks
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  42. How Very Smallchanges in the Peptide Sequence of β‑Amyloids Influence Their Redox Properties. Electrochemical Studies of Aβ(11-16) and pAβ(11-16)
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  43. Consequences of protein aggregation, underlying cellular and molecular mechanisms that lead to neurodegeneration
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  44. Imaging Alzheimer’s Disease Beyond Amyloid Plaques
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  45. Diagnostic and prognostic role of serum/plasma and CSF amyloid beta peptide levels in traumatic brain injury: a systematic review and meta-analysis
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