The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Investigating the Interaction of Cellulose Nanofibers Derived from Cotton with a Sophisticated 3D Human Lung Cell Coculture
Abstract
Cellulose nanofibers are an attractive component of a broad range of nanomaterials. Their intriguing mechanical properties and low cost, as well as the renewable nature of cellulose make them an appealing alternative to carbon nanotubes (CNTs), which may pose a considerable health risk when inhaled. Little is known, however, concerning the potential toxicity of aerosolized cellulose nanofibers. Using a 3D in vitro triple cell coculture model of the human epithelial airway barrier, it was observed that cellulose nanofibers isolated from cotton (CCN) elicited a significantly (p < 0.05) lower cytotoxicity and (pro-)inflammatory response than multiwalled CNTs (MWCNTs) and crocidolite asbestos fibers (CAFs). Electron tomography analysis also revealed that the intracellular localization of CCNs is different from that of both MWCNTs and CAFs, indicating fundamental differences between each different nanofibre type in their interaction with the human lung cell coculture. Thus, the data shown in the present study highlights that not only the length and stiffness determine the potential detrimental (biological) effects of any nanofiber, but that the material used can significantly affect nanofiber-cell interactions.
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Cites
Cellulose nanocrystals: chemistry, self-assembly, and applications
Habibi, Y., Lucia, L. A., & Rojas, O. J. (2010) · Chemical Reviews · doi:10.1021/cr900339w · Cited by 5,980
Monopoli, M. P., Walczyk, D., Campbell, A., Elia, G., Lynch, I., Baldelli Bombelli, F., & Dawson, K. A. (2011) · Journal of the American Chemical Society · doi:10.1021/ja107583h · Cited by 1,835
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Cited by
Current characterization methods for cellulose nanomaterials
Foster, E. J., Moon, R. J., Agarwal, U. P., Bortner, M. J., Bras, J., Camarero-Espinosa, S., Chan, K. J., Clift, M. J. D., Cranston, E. D., Eichhorn, S. J., et al. (2018) · Chemical Society Reviews · doi:10.1039/c6cs00895j · Cited by 1,021
Self-citationIsolation of Thermally Stable Cellulose Nanocrystals by Phosphoric Acid Hydrolysis
Camarero Espinosa, S., Kuhnt, T., Foster, E. J., & Weder, C. (2013) · Biomacromolecules · doi:10.1021/bm400219u · Cited by 665
Self-citationNanotechnology in agriculture: Opportunities, toxicological implications, and occupational risks
Iavicoli, I., Leso, V., Beezhold, D. H., & Shvedova, A. A. (2017) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2017.05.025 · Cited by 656
Sacui, I. A., Nieuwendaal, R. C., Burnett, D. J., Stranick, S. J., Jorfi, M., Weder, C., Foster, E. J., Olsson, R. T., & Gilman, J. W. (2014) · ACS Applied Materials & Interfaces · doi:10.1021/am500359f · Cited by 647
Self-citationCellulose nanocomposites: Fabrication and biomedical applications
Joseph, B., K, S. V., Sabu, C., Kalarikkal, N., & Thomas, S. (2020) · Journal of Bioresources and Bioproducts · doi:10.1016/j.jobab.2020.10.001 · Cited by 377
Metadata
- Authors
- Clift, M. J. D., Foster, E. J., Vanhecke, D., Studer, D., Wick, P., Gehr, P., Rothen-Rutishauser, B., & Weder, C.
- Venue
- Biomacromolecules
- Publisher
- American Chemical Society (ACS)
- Published
- 2011-09-06
- Volume
- 12
- Issue
- 10
- Pages
- 3666-3673
- ISSN
- 1525-7797 (ISSN-L)
- 1526-4602
- OpenAlex
- W1973315409
- Cited by
- 196
- References
- 3
- FWCI
- 4.07
- Type
- journal article
- Language
- en
- Open access
- closed
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- Clift, M. J. D., Foster, E. J., Vanhecke, D., Studer, D., Wick, P., Gehr, P., Rothen-Rutishauser, B., & Weder, C. (2011). Investigating the Interaction of Cellulose Nanofibers Derived from Cotton with a Sophisticated 3D Human Lung Cell Coculture. Biomacromolecules. https://doi.org/10.1021/bm200865j
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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