The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Breaking Down Lignin to High-Value Chemicals: The Conversion of Lignocellulose to Vanillin in a Gene Deletion Mutant of Rhodococcus jostii RHA1
Abstract
The aromatic polymer lignin represents a possible renewable source of aromatic chemicals, if biocatalytic routes for lignin breakdown can be developed. The availability of a genome sequence for Rhodococcus jostii RHA1, a bacterium that breaks down lignin, has allowed the application of a targeted pathway engineering strategy to lignin breakdown to produce vanillin, a valuable food/flavor chemical. A gene deletion strain of R. jostii RHA1 in which the vanillin dehydrogenase gene had been deleted, when grown on minimal medium containing 2.5% wheat straw lignocellulose and 0.05% glucose, was found to accumulate vanillin with yields of up to 96 mg/L after 144 h, together with smaller amounts of ferulic acid and 4-hydroxybenzaldehyde.
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Cites
The Catalytic Valorization of Lignin for the Production of Renewable Chemicals
Zakzeski, J., Bruijnincx, P. C. A., Jongerius, A. L., & Weckhuysen, B. M. (2010) · Chemical Reviews · doi:10.1021/cr900354u · Cited by 4,468
Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels
Atsumi, S., Hanai, T., & Liao, J. C. (2008) · Nature · doi:10.1038/nature06450 · Cited by 1,945
Cited by
A review on biopolymer production via lignin valorization
Rajesh Banu, J., Kavitha, S., Yukesh Kannah, R., Poornima Devi, T., Gunasekaran, M., Kim, S.-H., & Kumar, G. (2019) · Bioresource Technology · doi:10.1016/j.biortech.2019.121790 · Cited by 319
Xu, Z., Lei, P., Zhai, R., Wen, Z., & Jin, M. (2019) · Biotechnology for Biofuels · doi:10.1186/s13068-019-1376-0 · Cited by 276
Mohamed, E. T., Werner, A. Z., Salvachúa, D., Singer, C. A., Szostkiewicz, K., Rafael Jiménez-Díaz, M., Eng, T., Radi, M. S., Simmons, B. A., Mukhopadhyay, A., et al. (2020) · Metabolic Engineering Communications · doi:10.1016/j.mec.2020.e00143 · Cited by 136
Lignin depolymerization and biotransformation to industrially important chemicals/biofuels
Radhika, N. L., Sachdeva, S., & Kumar, M. (2022) · Fuel · doi:10.1016/j.fuel.2021.122935 · Cited by 88
Ding, Z., Ge, Y., Sar, T., Kumar, V., Harirchi, S., Binod, P., Sirohi, R., Sindhu, R., Wu, P., Lin, F., et al. (2023) · Bioresource Technology · doi:10.1016/j.biortech.2023.128793 · Cited by 26
Retracted
Metadata
- Authors
- Sainsbury, P. D., Hardiman, E. M., Ahmad, M., Otani, H., Seghezzi, N., Eltis, L. D., & Bugg, T. D. H.
- Venue
- ACS Chemical Biology
- Publisher
- American Chemical Society (ACS)
- Published
- 2013-08-08
- Volume
- 8
- Issue
- 10
- Pages
- 2151-2156
- ISSN
- 1554-8929 (ISSN-L)
- 1554-8937
- OpenAlex
- W2006826092
- Cited by
- 273
- References
- 2
- FWCI
- 11.93
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
