The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Prediction of Membrane Protein Types by Incorporating Amphipathic Effects
Abstract
According to their intramolecular arrangement and position in a cell, membrane proteins are generally classified into the following six types: (1) type I transmembrane, (2) type II transmembrane, (3) multipass transmembrane, (4) lipid chain-anchored membrane, (5) GPI-anchored membrane, and (6) peripheral membrane. Situated in a heteropolar environment, these six types of membrane proteins must have quite different amphiphilic sequence-order patterns in order to stabilize their respective frameworks. To incorporate such a feature into the predictor, the amphiphilic pseudo amino acid composition has been formulated that contains a series of hydrophobic and hydrophilic correlation factors. The success rates thus obtained have been remarkably enhanced in identifying the types of membrane proteins, as demonstrated by the jackknife test and independent data set test, respectively.
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Citations
Cites
Support vector machines for predicting membrane protein types by using functional domain composition
Cai, Y.-D., Zhou, G.-P., & Chou, K.-C. (2003) · Biophysical Journal · doi:10.1016/s0006-3495(03)70050-2 · Cited by 284
Self-citation
Cited by
Ensemble classifier for protein fold pattern recognition
Shen, H.-B., & Chou, K.-C. (2006) · Bioinformatics · doi:10.1093/bioinformatics/btl170 · Cited by 353
Self-citationJia, J., Liu, Z., Xiao, X., Liu, B., & Chou, K.-C. (2016) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2016.01.020 · Cited by 323
Self-citationZhou, X.-B., Chen, C., Li, Z.-C., & Zou, X.-Y. (2007) · Journal of Theoretical Biology · doi:10.1016/j.jtbi.2007.06.001 · Cited by 314
iRNA-PseU: Identifying RNA pseudouridine sites
Chen, W., Tang, H., Ye, J., Lin, H., & Chou, K.-C. (2016) · Molecular Therapy - Nucleic Acids · doi:10.1038/mtna.2016.37 · Cited by 291
Self-citationFeng, P., Ding, H., Yang, H., Chen, W., Lin, H., & Chou, K.-C. (2017) · Molecular Therapy - Nucleic Acids · doi:10.1016/j.omtn.2017.03.006 · Cited by 288
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Metadata
- Authors
- Chou, K.-C., & Cai, Y.-D.
- Venue
- Journal of Chemical Information and Modeling
- Publisher
- American Chemical Society (ACS)
- Published
- 2005-02-12
- Volume
- 45
- Issue
- 2
- Pages
- 407-413
- ISSN
- 1549-9596 (ISSN-L)
- 1549-960X
- OpenAlex
- W2118467383
- Cited by
- 175
- References
- 1
- FWCI
- 4.84
- Type
- journal article
- Language
- en
- Open access
- closed
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