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Cited by 163

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

BODIPY-Based Molecular Probe for Imaging of Cerebral β-Amyloid Plaques

Open access
Ono, Masahiro, Watanabe, Hiroyuki, Kimura, Hiroyuki, Saji, Hideo·2012·ACS Chemical Neuroscience

Abstract

We designed and synthesized a BODIPY-based probe (BAP-1) for the imaging of β-amyloid plaques in the brain. In binding experiments in vitro, BAP-1 showed excellent affinity for synthetic Aβ aggregates. β-Amyloid plaques in Tg2576 mouse brain were clearly visualized with BAP-1. In addition, the labeling of β-amyloid plaques was demonstrated in vivo in Tg2576 mice. These results suggest BAP-1 to be a useful fluorescent probe for the optical imaging of cerebral β-amyloid plaques in patients with Alzheimer's disease.

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Crossref · 10.1021/cn3000058

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Metadata

Authors
Ono, M., Watanabe, H., Kimura, H., & Saji, H.
Venue
ACS Chemical Neuroscience
Published
2012-02-17
Volume
3
Issue
4
Pages
319-324
ISSN
1948-7193 (ISSN-L)
OpenAlex
W235668762
Cited by
163
References
2
FWCI
6.04
Type
journal article
Language
en
Open access
green

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.