The DOI matches its Crossref record; 897 of the 901 references it cites were found in a registry or an index.
Functions, Therapeutic Applications, and Synthesis of Retinoids and Carotenoids
Abstract
ADVERTISEMENT RETURN TO ISSUEReviewNEXTFunctions, Therapeutic Applications, and Synthesis of Retinoids and CarotenoidsRosana Álvarez†, Belén Vaz†, Hinrich Gronemeyer‡, and Ángel R. de Lera*†View Author Information† Departamento de Química Orgánica, Centro de Investigación Biomédica (CINBIO), and Instituto de Investigación Biomédica de Vigo (IBIV), Universidade de Vigo, 36310 Vigo, Spain‡ Department of Functional Genomics and Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC)/CNRS/INSERM/ULP, BP 10142, 67404 Illkirch Cedex, C. U. de Strasbourg, France*E-mail: [email protected]Cite this: Chem. Rev. 2014, 114, 1, 1–125Publication Date (Web):November 22, 2013Publication History Received26 February 2013Published online22 November 2013Published inissue 8 January 2014https://pubs.acs.org/doi/10.1021/cr400126uhttps://doi.org/10.1021/cr400126ureview-articleACS PublicationsCopyright © 2013 American Chemical SocietyRequest reuse permissionsArticle Views8977Altmetric-Citations186LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Condensation,Hydrocarbons,Mixtures,Molecular structure,Organic compounds Get e-Alerts
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Treatment with vitamin A in these cases is not straight-forward, as there is a fear of accumulation of excessive amounts of toxic retinoids that are formed as byproducts of vitamin A pathways.”
From The Role of Vitamin A in Retinal Diseases (2022) · cites this paper as [9]
In the citing paper
“A good example of this toxicity is ABCA4-retinopathy where toxic products of vitamin A accumulate excessively in the retina [9,23,76,77,78].”
From The Role of Vitamin A in Retinal Diseases (2022) · cites this paper as [9]
In the citing paper
“Although abundant lipofuscin accumulation is involved in the aetiology of certain retinal diseases (e.g., AMD, Best disease and ABCA4-retinopathy), it accumulates at a lower level also with age in the RPE of healthy eyes [9,72,73,74,75].”
From The Role of Vitamin A in Retinal Diseases (2022) · cites this paper as [9]
Citations
Cites
1 retracted
Tang, G., Hu, Y., Yin, S., Wang, Y., Dallal, G. E., Grusak, M. A., & Russell, R. M. (2012) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.111.030775 · Cited by 146
RetractedPalladium-Catalyzed Cross-Coupling Reactions of Organoboron Compounds
Miyaura, N., & Suzuki, A. (1995) · Chemical Reviews · doi:10.1021/cr00039a007 · Cited by 12,960
Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor
Palczewski, K., Kumasaka, T., Hori, T., Behnke, C. A., Motoshima, H., Fox, B. A., Trong, I. L., Teller, D. C., Okada, T., Stenkamp, R. E., et al. (2000) · Science · doi:10.1126/science.289.5480.739 · Cited by 5,637
(1994) · New England Journal of Medicine · doi:10.1056/nejm199404143301501 · Cited by 4,737
Metal‐Catalyzed Cross‐Coupling Reactions
(2004) · Wiley eBooks · doi:10.1002/9783527619535 · Cited by 4,270
The Heck Reaction as a Sharpening Stone of Palladium Catalysis
Beletskaya, I. P., & Cheprakov, A. V. (2000) · Chemical Reviews · doi:10.1021/cr9903048 · Cited by 3,940
Crystal structure of oxygen-evolving photosystem II at a resolution of 1.9 Å
Umena, Y., Kawakami, K., Shen, J., & Kamiya, N. (2011) · Nature · doi:10.1038/nature09913 · Cited by 3,920
STILLE, J. K. (1986) · Angewandte Chemie International Edition in English · doi:10.1002/anie.198605081 · Cited by 3,397
Palladium‐Catalyzed Cross‐Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize
Seechurn, C. C. C. J., Kitching, M. O., Colacot, T. J., & Snieckus, V. A. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201107017 · Cited by 3,019
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
Chinchílla, R., & Nájera, C. (2007) · Chemical Reviews · doi:10.1021/cr050992x · Cited by 2,986
Flagged first, then by citations
4 of the 901 references couldn’t be matched to a known paper.
Research works printed but not linked: 42
- Litwack G., 2007, Vitamin A; Vitamins and Hormones, 75
- Imdad A., 2010, Cochrane Database Syst., CD008524
- IARC, 1998, Handbooks of Cancer Prevention: Carotenoids, 2
- Sporn M. B., 1984, The Retinoids
- Laudet V., 2002, The Nuclear Receptor Facts Book
- Bourguet W., 2010, Methods in Enzymology, 485
- Sporn M. B., 1983, Cancer Res., 43, 3034
- Britton G., 1995, Carotenoids. Part 1A. Isolation and Analysis
- Britton G., 1995, Carotenoids. Part 1B. Spectroscopy
- Britton G., 1996, Carotenoids. Part 2. Synthesis
- Britton G., 1998, Carotenoids, 3
- Dawson M. I., 2004, Curr. Med. Chem.: Anti-Cancer Agents, 4, 199
- Nomenclature of Carotenoids. IUPAC-IUB Joint Commission on Biochemical Nomenclature (JCBN), 1975, Pure Appl. Chem., 41, 407
- Ruiz F. X., 2012, Front. Pharmacol., 3, 58
- Chen Y., 1999, Cancer Res., 59, 3985
- Derguini F., 1986, Photochem. Photobiol., 13, 259
- Dawson M. I., 2012, Biochem. Biophys. Acta, Mol. Cell Biol. Lipids, 1821, 21
- Loeliger P., 1980, Eur. J. Med. Chem., 15, 9
- Nakayama Y., 2009, Anticancer Res., 29, 2059
- Pollard M., 1991, Cancer Res., 51, 3610
- Ziouzenkova O., 2007, Mol. Endocrinol., 21, 77, 10.1210/me.2006-0225 · DOI
- Gu Y., 2012, Topics in Current Chemistry, 327, 197
- Shchavlinskii A. N., 1982, Khim.-Farm. Zh., 16, 602
- Julia M., 1973, Bull. Chem. Soc. Fr., 110, 746
- Lee J. S., 2004, Synlett, 11, 1937
- Chemla F., 1993, Bull. Chem. Soc. Fr., 130, 200
- Maercker A., 1965, Org. React., 14, 270
- Wadsworth W. S., 1977, Org. React., 25, 73
- Vaz B., 2005, Synlett, 2, 294
- Sorg A., 2005, Synlett, 2, 289
- Ager D. J., 1990, Org. React., 38, 1
- Farina V., 1996, Advances in Metaloorganic Chemistry, 5
- Farina V., 1997, Organic Reactions
- Shapiro R. H., 1976, Org. React., 23, 405
- Chodkiewicz W., 1957, Ann. Chim., 2, 819
- Mariño-Ochoa E., 2002, Photochem. Photobiol., 76, 116, 10.1562/0031-8655(2002)076<0116:HEETFC>2.0.CO;2 · DOI
- Khachik F., 1997, Invest. Ophthalmol. Visual Sci., 38, 1802
- Minder E. I., 2009, Cell Mol. Biol., 55, 84
- Yamada T., 2012, Synlett, 20, 2980
- Tode C., 2001, J. Chem. Soc., Perkin Trans. 1, 24, 3338
- Lei X., 2012, Topics in Current Chemistry, 327, 163
- Han X., 2011, Front. Syst. Neurosci., 5, 18
Cited by
Sorted by citations
Leone, A., Spada, A., Battezzati, A., Schiraldi, A., Aristil, J., & Bertoli, S. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms160612791 · Cited by 807
Natural product and natural product derived drugs in clinical trials
Butler, M. S., Robertson, A. A. B., & Cooper, M. A. (2014) · Natural Product Reports · doi:10.1039/c4np00064a · Cited by 619
Bioactive Components in Moringa Oleifera Leaves Protect against Chronic Disease
Vergara-Jiménez, M. D. J., Almatrafi, M. M., & Fernández, M. L. (2017) · Antioxidants · doi:10.3390/antiox6040091 · Cited by 593
A new class of synthetic retinoid antibiotics effective against bacterial persisters
Kim, W., Zhu, W., Hendricks, G. L., Tyne, D. V., Steele, A. D., Keohane, C. E., Fricke, N., Conery, A. L., Shen, S., Pan, W., et al. (2018) · Nature · doi:10.1038/nature26157 · Cited by 412
Meléndez‐Martínez, A. J. (2019) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201801045 · Cited by 272
Metadata
- Authors
- Álvarez, R., Vaz, B., Gronemeyer, H., & de Lera, Á. R.
- Affiliations
- Universidade de Vigo (ES)
- Centre National de la Recherche Scientifique (FR)
- Corresponding author
- de Lera, Ángel R.
- Venue
- Chemical Reviews
- Publisher
- American Chemical Society (ACS)
- Published
- 2013-11-22
- Volume
- 114
- Issue
- 1
- Pages
- 1-125
- ISSN
- 0009-2665 (ISSN-L)
- 1520-6890
- OpenAlex
- W2008245372
- Cited by
- 260
- References
- 901
- Citations by year
- 2026: 17 · 2025: 19 · 2024: 21 · 2023: 18 · 2022: 28 · 2021: 14 · 2020: 27 · 2019: 24 · 2018: 20 · 2017: 18 · 2016: 27 · 2015: 15 · 2014: 12
- FWCI
- 1.69
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Chemical Reviews (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Retinoids in leukemia and cellular processes
- Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
- Physical Sciences › Chemistry › Organic Chemistry › Natural product bioactivities and synthesis
- Keywords
- retinoids, carotenoids, retinoid synthesis, carotenoid biosynthesis, vitamin A
- MeSH terms
- Alzheimer Disease, Animals, Antioxidants, Carotenoids, Humans, Metabolic Diseases, Neoplasms, Retinoids, Tretinoin, Vitamin A, Apoptosis, Reactive Oxygen Species, Receptors, Cytoplasmic and Nuclear, beta Carotene
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review