Recent Advances of Catalytic Asymmetric 1,3-Dipolar Cycloadditions

Peptidotriazoles on Solid Phase: [1,2,3]-Triazoles by Regiospecific Copper(I)-Catalyzed 1,3-Dipolar Cycloadditions of Terminal Alkynes to Azides

Tornøe, C. W., Christensen, C., & Meldal, M. (2002) · The Journal of Organic Chemistry · doi:10.1021/jo011148j · Cited by 8,696

1,3‐Dipolar Cycloadditions. Past and Future

Huisgen, R. (1963) · Angewandte Chemie International Edition in English · doi:10.1002/anie.196305651 · Cited by 2,929

Asymmetric 1,3-Dipolar Cycloaddition Reactions

Gothelf, K. V., & Jørgensen, K. A. (1998) · Chemical Reviews · doi:10.1021/cr970324e · Cited by 1,912

Brønsted-Acid-Catalyzed Asymmetric Multicomponent Reactions for the Facile Synthesis of Highly Enantioenriched Structurally Diverse Nitrogenous Heterocycles

Yu, J., Shi, F., & Gong, L.-Z. (2011) · Accounts of Chemical Research · doi:10.1021/ar2000343 · Cited by 903

Theory of 1,3-Dipolar Cycloadditions: Distortion/Interaction and Frontier Molecular Orbital Models

Ess, D. H., & Houk, K. N. (2008) · Journal of the American Chemical Society · doi:10.1021/ja800009z · Cited by 856

Organocatalytic Synthesis of Spiro[pyrrolidin-3,3′-oxindoles] with High Enantiopurity and Structural Diversity

Chen, X.-H., Wei, Q., Luo, S.-W., Xiao, H., & Gong, L.-Z. (2009) · Journal of the American Chemical Society · doi:10.1021/ja905302f · Cited by 577

Highly enantioselective synthesis and cellular evaluation of spirooxindoles inspired by natural products

Antonchick, A. P., Gerding-Reimers, C., Catarinella, M., Schürmann, M., Preut, H., Ziegler, S., Rauh, D., & Waldmann, H. (2010) · Nature Chemistry · doi:10.1038/nchem.730 · Cited by 569

New Strategies for Organic Catalysis: The First Enantioselective Organocatalytic 1,3-Dipolar Cycloaddition

Jen, W. S., Wiener, J. J. M., & MacMillan, D. W. C. (2000) · Journal of the American Chemical Society · doi:10.1021/ja005517p · Cited by 512

Catalytic Enantioselective 1,3-Dipolar Cycloadditions of Azomethine Ylides for Biology-Oriented Synthesis

Narayan, R., Potowski, M., Jia, Z.-J., Antonchick, A. P., & Waldmann, H. (2014) · Accounts of Chemical Research · doi:10.1021/ar400286b · Cited by 486

The Asymmetric Total Synthesis of (+)- and (−)-Spirotryprostatin B

Sebahar, P. R., & Williams, R. M. (2000) · Journal of the American Chemical Society · doi:10.1021/ja001133n · Cited by 434

Metal‐Free, Noncovalent Catalysis of Diels–Alder Reactions by Neutral Hydrogen Bond Donors in Organic Solvents and in Water

Wittkopp, A., & Schreiner, P. R. (2003) · Chemistry – A European Journal · doi:10.1002/chem.200390042 · Cited by 414

Recent advances in the catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides

Adrio, J., & Carretero, J. C. (2014) · Chem. Commun. · doi:10.1039/c4cc04381b · Cited by 373

Catalytic Asymmetric [3+2] Cycloaddition of Azomethine Ylides. Development of a Versatile Stepwise, Three-Component Reaction for Diversity-Oriented Synthesis

Chen, C., Li, X., & Schreiber, S. L. (2003) · Journal of the American Chemical Society · doi:10.1021/ja036558z · Cited by 289

Copper-Catalyzed Reaction of Terminal Alkynes with Nitrones. Selective Synthesis of 1-Aza-1-buten-3-yne and 2-Azetidinone Derivatives

Miura, M., Enna, M., Okuro, K., & Nomura, M. (1995) · The Journal of Organic Chemistry · doi:10.1021/jo00121a018 · Cited by 287

Asymmetric Copper(I)-Catalyzed Azide–Alkyne Cycloaddition to Quaternary Oxindoles

Zhou, F., Tan, C., Tang, J., Zhang, Y.-Y., Gao, W.-M., Wu, H.-H., Yu, Y.-H., & Zhou, J. (2013) · Journal of the American Chemical Society · doi:10.1021/ja4066656 · Cited by 184

Organocatalytic Diastereo‐ and Enantioselective 1,3‐Dipolar Cycloaddition of Azlactones and Methyleneindolinones

Sun, W., Zhu, G., Wu, C., Li, G., Hong, L., & Wang, R. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201302831 · Cited by 145

Catalytic asymmetric 1,3-dipolar cycloaddition of N-unprotected 2-oxoindolin-3-ylidene derivatives and azomethine ylides for the construction of spirooxindole-pyrrolidines

Liu, T., Xue, Z.-Y., Tao, H., & Wang, C. (2010) · Organic & Biomolecular Chemistry · doi:10.1039/c0ob00943a · Cited by 137

Catalytic Enantioselective Synthesis of Functionalized Tropanes Reveals Novel Inhibitors of Hedgehog Signaling

Narayan, R., Bauer, J. O., Strohmann, C., et al. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201307392 · Cited by 126

CuI–Fesulphos complexes: efficient chiral catalysts for asymmetric 1,3-dipolar cycloaddition of azomethine ylides

Cabrera, S., Arrayás, R. G., Martín‐Matute, B., Cossío, F. P., & Carretero, J. C. (2007) · Tetrahedron · doi:10.1016/j.tet.2007.03.130 · Cited by 123

Catalytic Asymmetric exo′‐Selective [3+2] Cycloaddition for Constructing Stereochemically Diversified Spiro[pyrrolidin‐3,3′‐oxindole]s

Awata, A., & Arai, T. (2012) · Chemistry - A European Journal · doi:10.1002/chem.201201249 · Cited by 121

Organocatalytic asymmetric multi-component [C+NC+CC] synthesis of highly functionalized pyrrolidine derivatives

Ibrahem, I., Rios, R., Veselý, J., & Córdova, A. (2007) · Tetrahedron Letters · doi:10.1016/j.tetlet.2007.07.031 · Cited by 115

A Convenient Procedure for the Catalytic Asymmetric 1,3-Dipolar Cycloaddition of Azomethine Ylides and Alkenes

Alemparte, C., Blay, G., & Jørgensen, K. A. (2005) · Organic Letters · doi:10.1021/ol0514653 · Cited by 112

Asymmetic Organocatalytic 1,3-Dipolar Cycloaddition of Azomethine Ylide to Methyl 2-(2-Nitrophenyl)acrylate for the Synthesis of Diastereoisomers of Spirotryprostatin A

Cheng, M., Wang, H., & Gong, L. (2011) · Organic Letters · doi:10.1021/ol200652j · Cited by 109

Origins of the Loss of Concertedness in Pericyclic Reactions: Theoretical Prediction and Direct Observation of Stepwise Mechanisms in [3 + 2] Thermal Cycloadditions

Vivanco, S., Lecea, B., Arrieta, A., Prieto, P., Morao, I., Linden, A., & Cossío, F. P. (2000) · Journal of the American Chemical Society · doi:10.1021/ja9945360 · Cited by 108

Enantioposition-Selective Copper-Catalyzed Azide–Alkyne Cycloaddition for Construction of Chiral Biaryl Derivatives

Osako, T., & Uozumi, Y. (2014) · Organic Letters · doi:10.1021/ol502778j · Cited by 97

Enantioselective 1,3-dipolar cycloaddition of methyleneindolinones and N,N′-cyclic azomethine imines

Hong, L., Kai, M., Wu, C., Sun, W., Zhu, G., Li, G., Yao, X., & Wang, R. (2013) · Chemical Communications · doi:10.1039/c3cc41507d · Cited by 96

Catalytic Asymmetric 1,3‐Dipolar Cycloadditions of Alkynes with Isatin‐Derived Azomethine Ylides: Enantioselective Synthesis of Spiro[indoline‐3,2′‐pyrrole] Derivatives

Shi, F. J., Zhu, R., Liang, X., & Tu, S. (2013) · Advanced Synthesis & Catalysis · doi:10.1002/adsc.201300366 · Cited by 88

Kinugasa reaction: an ‘ugly duckling’ of β-lactam chemistry

Stecko, S., Furman, B., & Chmielewski, M. (2014) · Tetrahedron · doi:10.1016/j.tet.2014.06.024 · Cited by 87

Dynamic One‐Pot Three‐Component Catalytic Asymmetric Transformation by Combination of Hydrogen‐Bond‐Donating and Amine Catalysts

Lin, S., Deiana, L., Zhao, G., Sun, J., & Córdova, A. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201101966 · Cited by 86

Organocatalytic and metal-mediated asymmetric [3+2] cycloaddition reactions

Xing, Y., & Wang, N. (2012) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2012.01.002 · Cited by 85

Catalytic Asymmetric Synthesis of α‐Quaternary Proline Derivatives by 1,3‐Dipolar Cycloaddition of α‐Silylimines

Hernández‐Toribio, J., Padilla, S., Adrio, J., & Carretero, J. C. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201203828 · Cited by 84

Chiral 2,6-Bis(oxazolinyl)pyridine−Rare Earth Metal Complexes as Catalysts for Highly Enantioselective 1,3-Dipolar Cycloaddition Reactions of 2-Benzopyrylium-4-olates

Suga, H., Inoue, K., Inoue, S., Kakehi, A., & Shiro, M. (2004) · The Journal of Organic Chemistry · doi:10.1021/jo049007f · Cited by 82

Nickel(II)‐Catalyzed Enantioselective 1,3‐Dipolar Cycloaddition of Azomethine Imines with Alkylidene Malonates

Li, J., Lian, X., Liu, X., Lin, L., & Feng, X. (2013) · Chemistry - A European Journal · doi:10.1002/chem.201203891 · Cited by 81

Asymmetric Synthesis of Spiro[isoxazolin-3,3′-oxindoles] via the Catalytic 1,3-Dipolar Cycloaddition Reaction of Nitrile Oxides

Lian, X., Guo, S., Wang, G., Lin, L., Liu, X., & Feng, X. (2014) · The Journal of Organic Chemistry · doi:10.1021/jo5012625 · Cited by 81

Enantioselective synthesis of the spirotryprostatin A scaffold

Antonchick, A. P., Schuster, H., Bruss, H., Schürmann, M., Preut, H., Rauh, D., & Waldmann, H. (2011) · Tetrahedron · doi:10.1016/j.tet.2011.04.056 · Cited by 68

Asymmetric Synthesis of trans‐β‐Lactams by a Kinugasa Reaction on Water

Chen, Z., Lin, L., Wang, M., Liu, X., & Feng, X. (2013) · Chemistry - A European Journal · doi:10.1002/chem.201204373 · Cited by 62

Chiral amplification in Diels-Alder and 1,3-dipolar cycloadditions catalyzed by bis(oxazoline)-Zn(II)-based chiral complexes

Crosignani, S., Desimoni, G., Faita, G., Filippone, S., Mortoni, A., Righetti, P., & Zema, M. (1999) · Tetrahedron Letters · doi:10.1016/s0040-4039(99)01425-2 · Cited by 60

Enantioselective synthesis of 4-aminopyrrolidine-2,4-dicarboxylate derivatives via Ag-catalyzed cycloaddition of azomethine ylides with alkylidene azlactones

González‐Esguevillas, M., Adrio, J., & Carretero, J. C. (2013) · Chemical Communications · doi:10.1039/c3cc41663a · Cited by 58

Catalytic Asymmetric Construction of Quaternary α‐Amino Acid Containing Pyrrolidines through 1,3‐Dipolar Cycloaddition of Azomethine Ylides to α‐Aminoacrylates

Wang, Z., Luo, S., Zhang, S., Yang, W., Liu, Y., Li, H., Luo, X., & Deng, W. (2013) · Chemistry - A European Journal · doi:10.1002/chem.201300204 · Cited by 53

Asymmetric Multicomponent [C+NC+CC] Synthesis of Highly Functionalized Pyrrolidines Catalyzed by Silver(I)

Garner, P., Kanıskan, H. Ü., Hu, J., Youngs, W. J., & Panzner, M. J. (2006) · Organic Letters · doi:10.1021/ol061113b · Cited by 51

X=Y-ZH Systems as potential 1,3-dipoles. Part 39. Metallo-azomethine ylides from aliphatic aldimines. Facile regio- and stereo-specific cycloaddition reactions

Grigg, R., Montgomery, J., & Somasunderam, A. (1992) · Tetrahedron · doi:10.1016/s0040-4020(01)88346-0 · Cited by 50

Stereoselective Construction of Spiro(butyrolactonepyrrolidines) by Highly Efficient Copper(I)/TF‐BiphamPhos‐Catalyzed Asymmetric 1,3‐Dipolar Cycloaddition

Liu, T., He, Z., Tao, H., & Wang, C. (2012) · Chemistry - A European Journal · doi:10.1002/chem.201103876 · Cited by 50

Highly Enantioselective Construction of Polycyclic Spirooxindoles by Organocatalytic 1,3‐Dipolar Cycloaddition of 2‐Cyclohexenone Catalyzed by Proline‐Sulfonamide

Xiao, J., Liu, Q., Ren, J., Liu, J., Carter, R. G., Chen, X., & Yang, H. (2014) · European Journal of Organic Chemistry · doi:10.1002/ejoc.201402953 · Cited by 44

Asymmetric cycloaddition reactions between 2-benzopyrylium-4-olates and 3-(2-alkenoyl)-2-oxazolidinones in the presence of 2,6-bis(oxazolinyl)pyridine-lanthanoid complexes

Suga, H., Suzuki, T., Inoue, K., & Kakehi, A. (2006) · Tetrahedron · doi:10.1016/j.tet.2006.07.028 · Cited by 40

An efficient, one-pot, three-component procedure for the synthesis of chiral spirooxindolopyrrolizidines via catalytic highly enantioselective 1,3-dipolar cycloaddition

Salahi, F., Taghizadeh, M. J., Arvinnezhad, H., Moemeni, M., Jadidi, K., & Notash, B. (2013) · Tetrahedron Letters · doi:10.1016/j.tetlet.2013.11.097 · Cited by 37

Tetranuclear titanium 7,7′‐modified binaphtholate cluster as a novel chiral Lewis acid catalyst

Mikami, K., Ueki, M., Matsumoto, Y., & Terada, M. (2001) · Chirality · doi:10.1002/chir.1174 · Cited by 35

Brönsted and Lewis acid catalysis of XY–ZH cycloadditions

Grigg, R., & Gunaratne, H. Q. N. (1982) · Journal of the Chemical Society Chemical Communications · doi:10.1039/c39820000384 · Cited by 35

A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective ligation of azides and terminal alkynes

Rostovtsev, V. V., Green, L. G., Fokin, V. V., & Sharpless, K. B. (2002) · Angewandte Chemie International Edition · doi:10.1002/1521-3773(20020715)41:14<2596::aid-anie2596>3.0.co;2-4

Asymmetric Cycloaddition and Cyclization Reactions Catalyzed by Chiral N,N′-Dioxide–Metal Complexes

Liu, X., Zheng, H., Xia, Y., Lin, L., & Feng, X. (2017) · Accounts of Chemical Research · doi:10.1021/acs.accounts.7b00377 · Cited by 485

Metal-catalyzed regiodivergent organic reactions

Nájera, C., Beletskaya, I. P., & Yus, M. (2019) · Chemical Society Reviews · doi:10.1039/c8cs00872h · Cited by 304

Consecutive multicomponent reactions for the synthesis of complex molecules

Zhi, S., Ma, X., & Zhang, W. (2019) · Organic & Biomolecular Chemistry · doi:10.1039/c9ob00772e · Cited by 293