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Biodegradation and Adsorption of Antibiotics in the Activated Sludge Process

Li, Bing, Zhang, Tong·2010·Environmental Science & Technology

Abstract

The removal of 11 antibiotics of 6 classes, that is, two beta-lactams (ampicillin and cefalexin), two sulfonamides (sulfamethoxazole and sulfadiazine), three fluoroquinolones (norfloxacin, ofloxacin, and ciprofloxacin), one tetracyclines (tetracycline), two macorlides (roxithromycin and anhydro-erythromycin), and one others (trimethoprim), in activated sludge process was investigated using two series of batch reactors treating freshwater and saline sewage respectively. At environmental relevant concentrations tested in this study, biodegradation and adsorption were the major removal routes for the target antibiotics, where volatilization and hydrolysis were neglectable. Among the 11 target antibiotics, cefalexin and the two sulfonamides were predominantly removed by biodegradation in both freshwater and saline sewage systems. Ampicillin, norfloxacin, ciprofloxacin, ofloxacin, tetracycline, roxithromycin, and trimethoprim were mainly removed by adsorption. Divalent cations (Ca(2+) and Mg(2+)) in saline sewage significantly decreased the adsorption of the three fluoroquinolones onto activated sludge. These three fluoroquinolones also exhibited certain biodegradability in the saline activated sludge reactor. Erythromycin-H(2)O was persistent in both saline and freshwater systems under the experimental conditions and could not be removed at all. Kinetics study showed that biodegradation of cefalexin, the two sulfonamides and the three fluoroquinolones followed first-order model well (R(2): 0.921-0.997) with the rate constants ranging from 5.2 x 10(-3) to 3.6 x 10(-1) h(-1).

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Metadata

Authors
Li, B., & Zhang, T.
Venue
Environmental Science & Technology
Published
2010-04-12
Volume
44
Issue
9
Pages
3468-3473
ISSN
  • 0013-936X (ISSN-L)
  • 1520-5851
OpenAlex
W2041919346
Cited by
953
References
1
FWCI
27.48
Type
journal article
Language
en
Open access
closed

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Li, B., & Zhang, T. (2010). Biodegradation and Adsorption of Antibiotics in the Activated Sludge Process. Environmental Science & Technology. https://doi.org/10.1021/es903490h

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