2,3-Oxidosqualene, an Intermediate in the Biological Synthesis of Sterols from Squalene1
Abstract
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT2,3-Oxidosqualene, an Intermediate in the Biological Synthesis of Sterols from Squalene1E. J. Corey, William E. Russey, and Paul R. Ortiz de MontellanoCite this: J. Am. Chem. Soc. 1966, 88, 20, 4750–4751Publication Date (Print):October 1, 1966Publication History Published online1 May 2002Published inissue 1 October 1966https://pubs.acs.org/doi/10.1021/ja00972a056https://doi.org/10.1021/ja00972a056research-articleACS PublicationsRequest reuse permissionsArticle Views1103Altmetric-Citations190LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked In…
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Cholesterol homeostasis is maintained by negative feedback regulation of genes and their encoded enzymes in the pathway, including the rate-limiting enzymes HMGCR and SQLE.
“Cholesterol homeostasis is maintained by negative feedback regulation of genes and their encoded enzymes in the pathway, including the rate limiting enzymes HMG CoA reductase (HMGCR) and SQLE20–22.”
From A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett syndrome (2013) · cites this paper as [21]
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Studies on Squalene Epoxidase of Rat Liver
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- Authors
- Corey, E. J., Russey, W. E., & de Montellano, P. R. O.
- ORCID
- Corey, E. J.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 1966-10
- Volume
- 88
- Issue
- 20
- Pages
- 4750-4751
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2049714108
- Cited by
- 225
- References
- 0
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 1 · 2023: 1 · 2022: 4 · 2021: 3 · 2020: 3 · 2019: 1 · 2018: 2 · 2017: 3 · 2016: 6 · 2015: 4 · 2013: 6 · 2012: 2
- FWCI
- 9.99
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the American Chemical Society (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Steroid Chemistry and Biochemistry
- Health Sciences › Medicine › Surgery › Cholesterol and Lipid Metabolism
- Keywords
- 2,3-oxidosqualene, squalene, sterol biosynthesis, squalene epoxidation, natural product synthesis
- MeSH terms
- Animals, Chemistry, Chromatography, Squalene, Sterols, Rats, Chemical Phenomena, In Vitro Techniques
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