Cited by 225Plant biochemistry and biosynthesisSteroid Chemistry and BiochemistryCholesterol and Lipid Metabolism

2,3-Oxidosqualene, an Intermediate in the Biological Synthesis of Sterols from Squalene1

Corey, E. J., Russey, William E., de Montellano, Paul R. Ortiz·1966·Journal of the American Chemical Society

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT2,3-Oxidosqualene, an Intermediate in the Biological Synthesis of Sterols from Squalene1E. J. Corey, William E. Russey, and Paul R. Ortiz de MontellanoCite this: J. Am. Chem. Soc. 1966, 88, 20, 4750–4751Publication Date (Print):October 1, 1966Publication History Published online1 May 2002Published inissue 1 October 1966https://pubs.acs.org/doi/10.1021/ja00972a056https://doi.org/10.1021/ja00972a056research-articleACS PublicationsRequest reuse permissionsArticle Views1103Altmetric-Citations190LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked In…

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  • Cholesterol homeostasis is maintained by negative feedback regulation of genes and their encoded enzymes in the pathway, including the rate-limiting enzymes HMGCR and SQLE.

    “Cholesterol homeostasis is maintained by negative feedback regulation of genes and their encoded enzymes in the pathway, including the rate limiting enzymes HMG CoA reductase (HMGCR) and SQLE20–22.”

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Authors
Corey, E. J., Russey, W. E., & de Montellano, P. R. O.
Venue
Journal of the American Chemical Society
Published
1966-10
Volume
88
Issue
20
Pages
4750-4751
ISSN
  • 0002-7863 (ISSN-L)
  • 1520-5126
OpenAlex
W2049714108
Cited by
225
References
0
Citations by year
2026: 2 · 2025: 4 · 2024: 1 · 2023: 1 · 2022: 4 · 2021: 3 · 2020: 3 · 2019: 1 · 2018: 2 · 2017: 3 · 2016: 6 · 2015: 4 · 2013: 6 · 2012: 2
FWCI
9.99
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of the American Chemical Society (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Steroid Chemistry and Biochemistry
  • Health Sciences › Medicine › Surgery › Cholesterol and Lipid Metabolism
Keywords
2,3-oxidosqualene, squalene, sterol biosynthesis, squalene epoxidation, natural product synthesis
MeSH terms
Animals, Chemistry, Chromatography, Squalene, Sterols, Rats, Chemical Phenomena, In Vitro Techniques

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