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Light-Induced Modulation of Self-Assembly on Spiropyran-Capped Gold Nanoparticles: A Potential System for the Controlled Release of Amino Acid Derivatives

Ipe, Binil Itty, Mahima, S., Thomas, K. George·2003·Journal of the American Chemical Society

Abstract

A photoswitchable double-shell structure on Au nanoparticles, consisting of photochromic spiropyran as the first shell, which regulates the assembly and release of an outer shell of amino acid derivatives upon irradiation, is being reported for the first time. The light-regulated changes in the topographic properties of spiropyran-capped Au nanoparticles (i.e., interconversion between the zwitterionic and neutral forms) are exploited for the assembly and release of amino acid-based therapeutic agents such as l-DOPA.

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Authors
Ipe, B. I., Mahima, S., & Thomas, K. G.
Venue
Journal of the American Chemical Society
Published
2003-05-23
Volume
125
Issue
24
Pages
7174-7175
ISSN
  • 0002-7863 (ISSN-L)
  • 1520-5126
OpenAlex
W2087698664
Cited by
177
References
0
FWCI
4.24
Type
journal article
Language
en
Open access
closed

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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