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Synthesis of Water-Dispersible Fluorescent, Radio-Opaque, and Paramagnetic CdS:Mn/ZnS Quantum Dots: A Multifunctional Probe for Bioimaging
Abstract
Ultra-small (3.1 nm) multifunctional CdS:Mn/ZnS core-shell semiconductor quantum dots (Qdots), which possess fluorescent, radio-opacity, and paramagnetic properties, have been shown here. To demonstrate in vivo bioimaging capability, a rat was administered endovascularly with Qdots conjugated with a TAT peptide. The labeling efficacy of these Qdots was demonstrated on the basis of the histological analysis of the microtome sliced brain tissue, clearly showing that TAT-conjugated Qdots stained brain blood vessels.
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Cites
Tunable Near-Infrared Optical Gain and Amplified Spontaneous Emission Using PbSe Nanocrystals
Schaller, R. D., Petruska, M. A., & Klimov, V. I. (2003) · The Journal of Physical Chemistry B · doi:10.1021/jp0311660 · Cited by 321
Cited by
Quantum Dots and Their Multimodal Applications: A Review
Bera, D., Qian, L., Tseng, T.-K., & Holloway, P. H. (2010) · Materials · doi:10.3390/ma3042260 · Cited by 1,365
Self-citationMultimodality Imaging Probes: Design and Challenges
Louie, A. (2010) · Chemical Reviews · doi:10.1021/cr9003538 · Cited by 1,044
Doped quantum dots for chemo/biosensing and bioimaging
Wu, P., & Yan, X.-P. (2013) · Chemical Society Reviews · doi:10.1039/c3cs60017c · Cited by 667
“SMART” Drug Delivery Systems: Double-Targeted pH-Responsive Pharmaceutical Nanocarriers
Sawant, R. M., Hurley, J. P., Salmaso, S., Kale, A., Tolcheva, E., Levchenko, T. S., & Torchilin, V. P. (2006) · Bioconjugate Chemistry · doi:10.1021/bc060080h · Cited by 540
van Schooneveld, M. M., Vucic, E., Koole, R., Zhou, Y., Stocks, J., Cormode, D. P., Tang, C. Y., Gordon, R. E., Nicolay, K., Meijerink, A., et al. (2008) · Nano Letters · doi:10.1021/nl801596a · Cited by 256
Metadata
- Authors
- Santra, S., Yang, H., Holloway, P. H., Stanley, J. T., & Mericle, R. A.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2005-01-21
- Volume
- 127
- Issue
- 6
- Pages
- 1656-1657
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2091436279
- Cited by
- 327
- References
- 1
- FWCI
- 14.71
- Type
- journal article
- Language
- en
- Open access
- closed
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- Santra, S., Yang, H., Holloway, P. H., Stanley, J. T., & Mericle, R. A. (2005). Synthesis of Water-Dispersible Fluorescent, Radio-Opaque, and Paramagnetic CdS:Mn/ZnS Quantum Dots: A Multifunctional Probe for Bioimaging. Journal of the American Chemical Society. https://doi.org/10.1021/ja0464140
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