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Cited by 891

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Nanoscale Metal−Organic Frameworks as Potential Multimodal Contrast Enhancing Agents

Open access
Rieter, William J., Taylor, Kathryn M. L., An, Hongyu, Lin, Weili, Lin, Wenbin·2006·Journal of the American Chemical Society
DOI 10.1021/ja0627444
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Abstract

Nanoscale metal-organic frameworks (NMOFs) based on Gd3+ centers and benzenedicarboxylate and benzenetricarboxylate bridging ligands were synthesized using reverse microemulsions and characterized using SEM, PXRD, and TGA. These NMOFs exhibit extraordinarily large R1 and R2 relaxivities because of the presence of up to tens of millions of Gd3+ centers in each nanoparticle and are thus efficient T1 and T2 contrast agents for MRI. The NMOFs can also be made highly luminescent by doping with Eu3+ or Tb3+ centers. The results from this work suggest that NMOFs can be used as potential contrast agents for multimodal imaging.

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Metadata

Authors
Rieter, W. J., Taylor, K. M. L., An, H., Lin, W., & Lin, W.
Venue
Journal of the American Chemical Society
Publisher
American Chemical Society (ACS)
Published
2006-06-27
Volume
128
Issue
28
Pages
9024-9025
ISSN
  • 0002-7863 (ISSN-L)
  • 1520-5126
DOI
10.1021/ja0627444
OpenAlex
W1967551950
Cited by
891
References
0
FWCI
23.64
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Nanoscale Metal−Organic Frameworks as Potential Multimodal Contrast Enhancing Agents. https://app.cochat.ai/papers/10.1021/ja0627444
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Rieter, W. J., Taylor, K. M. L., An, H., Lin, W., & Lin, W. (2006). Nanoscale Metal−Organic Frameworks as Potential Multimodal Contrast Enhancing Agents. Journal of the American Chemical Society. https://doi.org/10.1021/ja0627444

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