The DOI matches its Crossref record.
Catalytic Intermolecular Amination of C−H Bonds: Method Development and Mechanistic Insights
Abstract
Reaction methodology for intermolecular C-H amination of benzylic and 3 degrees C-H bonds is described. This process uses the starting alkane as the limiting reagent, gives optically pure tetrasubstituted amines through stereospecific insertion into enantiomeric 3 degrees centers, displays high chemoselectivity for benzylic oxidation, and enables the facile preparation of isotopically enriched 15N-labeled compounds. Access to substituted amines, amino alcohols, and diamines is thereby made possible in a single transformation. Important information relevant to understanding the initial steps in the catalytic cycle, reaction chemoselectivity, the nature of the active oxidant, and pathways for catalyst inactivation has been gained through mechanistic analysis; these studies are also presented.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion
Davies, H. M. L., & Manning, J. R. (2008) · Nature · doi:10.1038/nature06485 · Cited by 2,303
Inamoto, K., Hasegawa, C., Hiroya, K., & Doi, T. (2008) · Organic Letters · doi:10.1021/ol802033p · Cited by 290
Chemo- and site-selective derivatizations of natural products enabling biological studies
Robles, O., & Romo, D. (2014) · Nat. Prod. Rep. · doi:10.1039/c3np70087a · Cited by 154
Metadata
- Authors
- Fiori, K. W., & Du Bois, J.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2007-01-01
- Volume
- 129
- Issue
- 3
- Pages
- 562-568
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2052015737
- Cited by
- 462
- References
- 0
- FWCI
- 18.41
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Catalytic Intermolecular Amination of C−H Bonds: Method Development and Mechanistic Insights. https://app.cochat.ai/papers/10.1021/ja0650450
- The paper
- Fiori, K. W., & Du Bois, J. (2007). Catalytic Intermolecular Amination of C−H Bonds: Method Development and Mechanistic Insights. Journal of the American Chemical Society. https://doi.org/10.1021/ja0650450
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
