The Amyloid Formation Mechanism in Human IAPP: Dimers Have β-Strand Monomer−Monomer Interfaces

Dupuis, Nicholas F., Wu, Chun, Shea, Joan-Emma, Bowers, Michael T.·2011·Journal of the American Chemical Society

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  2. Prion Protein-Derived Cell-Penetrating Peptide Inhibits Type II Diabetes-Associated Islet Amyloid Polypeptide Aggregation and Cytotoxicity
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    Anne Pfitzer, Celina M. Schulz, Robin Backer, Filip Hasecke, Lothar Gremer, Wolfgang Hoyer · 2026 · Biophysical Chemistry
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    Aleksandra Antevska, Connor Christopher Long, Samuel D. Dupuy, J. Jason Collier, Michael D. Karlstad, Thanh D. Do · 2022 · Journal of Proteome Research
  5. Deciphering the impact of F23L mutation on the aggregation propensity of human islet amyloid polypeptide using molecular simulations
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  6. Structural Characterization of Protein Complexes Using Native Mass Spectrometry
    Kazumi Saikusa · 2024 · Journal of the Mass Spectrometry Society of Japan
  7. Inhibitory mechanism of lithospermic acid on the fibrillation of type 2 diabetes associated islet amyloid polypeptide
    Anisha Manchanda, Bhupesh Goyal · 2025 · Journal of Molecular Graphics and Modelling
  8. Impact of glucagon oxidation on fibril formation
    Aleksandra Antevska, Gaoyuan Lu, Emmanuel Nkyaagye, Sarah S. Hirschbeck, Connor Christopher Long, Lingjun Li, Thanh D. Do · 2025 · International Journal of Mass Spectrometry
  9. Molecular mechanisms of amyloid aggregation in human proteinopathies
    Bertrand Morel, Francisco Conejero‐Lara · 2020 · Elsevier eBooks
  10. Stability Analysis of Human Islet Amyloid Polypeptide and Its Mutated Oligomeric Forms
    Ashok Kumar, Kanika Gupta, Amit Pal · 2015 · Journal of Neurology and Neurological Disorders
  11. Conformational Changes of the Wild-Type hIAPP and the S20P Mutant in Water Revealed by Molecular Dynamics Simulations
    Mian Wang, Jian Yi Wang · 2011 · Advanced materials research
  12. Développement de techniques physiques et chimiques pour l’étude et l’inhibition de l’oligomérisation et de l’agrégation de IAPP : intérêt dans le diabète de type II
    Corentin Berardet · 2018
  13. Fine-Tuning hIAPP Amyloidogenesis: Probing Molecular Mechanisms via Fluorinated Core Substitutions
    Artem Pavlov, Hossein Batebi, Nicklas Österlund, Kevin Pagel, Boris Schade, Mario Schubert, Roland R. Netz, Beate Koksch · 2026 · ACS Bio & Med Chem Au
  14. Delineating the structural distortions in hIAPP protofibrils by rationally designed hexapeptides using computer simulations
    Tanishka Mehta, Bhupesh Goyal · 2026 · Physical Chemistry Chemical Physics
  15. Decongested 2D IR Spectra Reveal N-Terminal Helices in Amyloid Oligomers Associated with Type 2 Diabetes
    Shivani T. Shivani, Josée Maurais, Brynn E. LeMasters, Harrison J. Esterly, Martin T. Zanni · 2026 · Journal of the American Chemical Society
  16. Native Ion Mobility–Mass Spectrometry Reports Kinetically Trapped Conformational Ensembles, Not Single Structures
    Christian Bleiholder, Fanny C. Liu · 2026 · Journal of the American Society for Mass Spectrometry