The Amyloid Formation Mechanism in Human IAPP: Dimers Have β-Strand Monomer−Monomer Interfaces
Dupuis, Nicholas F., Wu, Chun, Shea, Joan-Emma, Bowers, Michael T.·2011·Journal of the American Chemical Society
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- Prion Protein-Derived Cell-Penetrating Peptide Inhibits Type II Diabetes-Associated Islet Amyloid Polypeptide Aggregation and CytotoxicityYujeong Oh, Loganathan Palanikumar, Madeline Howarth, Debabrata Maity, Liaqat Ali, Morad Mustafa, Sunil Kumar, Andrew D. Hamilton, Mazin M. Magzoub · 2026 · Biochemistry
- An islet amyloid polypeptide oligomer model inhibits fibril formationAnne Pfitzer, Celina M. Schulz, Robin Backer, Filip Hasecke, Lothar Gremer, Wolfgang Hoyer · 2026 · Biophysical Chemistry
- Mouse Pancreatic Peptide Hormones Probed at the Sub-Single-Islet Level: The Effects of Acute Corticosterone TreatmentAleksandra Antevska, Connor Christopher Long, Samuel D. Dupuy, J. Jason Collier, Michael D. Karlstad, Thanh D. Do · 2022 · Journal of Proteome Research
- Deciphering the impact of F23L mutation on the aggregation propensity of human islet amyloid polypeptide using molecular simulationsAnisha Manchanda, Bhupesh Goyal · 2024 · Journal of Molecular Liquids
- Structural Characterization of Protein Complexes Using Native Mass SpectrometryKazumi Saikusa · 2024 · Journal of the Mass Spectrometry Society of Japan
- Inhibitory mechanism of lithospermic acid on the fibrillation of type 2 diabetes associated islet amyloid polypeptideAnisha Manchanda, Bhupesh Goyal · 2025 · Journal of Molecular Graphics and Modelling
- Impact of glucagon oxidation on fibril formationAleksandra Antevska, Gaoyuan Lu, Emmanuel Nkyaagye, Sarah S. Hirschbeck, Connor Christopher Long, Lingjun Li, Thanh D. Do · 2025 · International Journal of Mass Spectrometry
- Molecular mechanisms of amyloid aggregation in human proteinopathiesBertrand Morel, Francisco Conejero‐Lara · 2020 · Elsevier eBooks
- Stability Analysis of Human Islet Amyloid Polypeptide and Its Mutated Oligomeric FormsAshok Kumar, Kanika Gupta, Amit Pal · 2015 · Journal of Neurology and Neurological Disorders
- Conformational Changes of the Wild-Type hIAPP and the S20P Mutant in Water Revealed by Molecular Dynamics SimulationsMian Wang, Jian Yi Wang · 2011 · Advanced materials research
- Développement de techniques physiques et chimiques pour l’étude et l’inhibition de l’oligomérisation et de l’agrégation de IAPP : intérêt dans le diabète de type IICorentin Berardet · 2018
- Fine-Tuning hIAPP Amyloidogenesis: Probing Molecular Mechanisms via Fluorinated Core SubstitutionsArtem Pavlov, Hossein Batebi, Nicklas Österlund, Kevin Pagel, Boris Schade, Mario Schubert, Roland R. Netz, Beate Koksch · 2026 · ACS Bio & Med Chem Au
- Delineating the structural distortions in hIAPP protofibrils by rationally designed hexapeptides using computer simulationsTanishka Mehta, Bhupesh Goyal · 2026 · Physical Chemistry Chemical Physics
- Decongested 2D IR Spectra Reveal N-Terminal Helices in Amyloid Oligomers Associated with Type 2 DiabetesShivani T. Shivani, Josée Maurais, Brynn E. LeMasters, Harrison J. Esterly, Martin T. Zanni · 2026 · Journal of the American Chemical Society
- Native Ion Mobility–Mass Spectrometry Reports Kinetically Trapped Conformational Ensembles, Not Single StructuresChristian Bleiholder, Fanny C. Liu · 2026 · Journal of the American Society for Mass Spectrometry