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Cited by 211

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Enhanced Mechanical Rigidity of Hydrogels Formed from Enantiomeric Peptide Assemblies

Open access
Nagy, Katelyn J., Giano, Michael C., Jin, Albert, Pochan, Darrin J., Schneider, Joel P.·2011·Journal of the American Chemical Society

Abstract

Chirality can be used as a design tool to control the mechanical rigidity of hydrogels formed from self-assembling peptides. Hydrogels prepared from enantiomeric mixtures of self-assembling β-hairpins show nonadditive, synergistic, enhancement in material rigidity compared to gels prepared from either pure enantiomer, with the racemic hydrogel showing the greatest effect. CD spectroscopy, TEM, and AFM indicate that this enhancement is defined by nanoscale interactions between enantiomers in the self-assembled state.

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Metadata

Authors
Nagy, K. J., Giano, M. C., Jin, A., Pochan, D. J., & Schneider, J. P.
Venue
Journal of the American Chemical Society
Published
2011-09-07
Volume
133
Issue
38
Pages
14975-14977
ISSN
  • 0002-7863 (ISSN-L)
  • 1520-5126
OpenAlex
W2052193935
Cited by
211
References
1
FWCI
4.07
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Enhanced Mechanical Rigidity of Hydrogels Formed from Enantiomeric Peptide Assemblies. https://app.cochat.ai/papers/10.1021/ja206742m
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Nagy, K. J., Giano, M. C., Jin, A., Pochan, D. J., & Schneider, J. P. (2011). Enhanced Mechanical Rigidity of Hydrogels Formed from Enantiomeric Peptide Assemblies. Journal of the American Chemical Society. https://doi.org/10.1021/ja206742m

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