Bifunctional Compounds for Controlling Metal-Mediated Aggregation of the Aβ42Peptide

Sharma, Anuj K., Pavlova, Stephanie T., Kim, Jaekwang, Finkelstein, Darren, Hawco, Nicholas J., Rath, Nigam P., Kim, Jungsu, Mirica, Liviu M.·2012·Journal of the American Chemical Society

DOI 10.1021/ja210588m

Cited by (202)

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Jiang‐Yang Shao, Si‐Hai Wu, Junjie Ma · 2020 · Chemical Communications
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Orkid Coskuner‐Weber · 2016 · JBIC Journal of Biological Inorganic Chemistry
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Xuesong Wang, Lei He, Cong Zhao, Weihong Du, Jun Xiong Lin · 2013 · JBIC Journal of Biological Inorganic Chemistry
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Srinivasarao Yaragorla, Ravikrishna Dada, Garima Singh · 2016 · ChemistrySelect
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Alzheimer’s Disease, Drosophila melanogaster and Polyphenols
Marlene Jiménez-Del-Río, Carlos Velez‐Pardo · 2015 · Advances in experimental medicine and biology
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Ardeshir Shokrollahi, Fereshteh Zarghampour, Sima Akbari, Ayda Salehi · 2015 · Analytical Methods
Platinoid complexes to target monomeric disordered peptides: a forthcoming solution against amyloid diseases?
Christelle Hureau, Peter Faller · 2014 · Dalton Transactions
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Yonghwan Ji, Hyuck Jin Lee, Minjeong Kim, Geewoo Nam, Shin Jung C. Lee, Jaeheung Cho, Cheol‐Min Park, Mi Hee Lim · 2017 · Inorganic Chemistry
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Elżbieta Studzińska-Sroka, Magdalena Bulicz, Marika Henkel, Natalia Rosiak, Magdalena Paczkowska‐Walendowska, Dominik Szwajgier, Ewa Baranowska‐Wójcik, Katarzyna Korybalska, Judyta Cielecka‐Piontek · 2023 · Molecules
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Sefat A. Alwarsh, Kolawole Ayinuola, Silvana S. Dormi, Matthias C. McIntosh · 2012 · Organic Letters
Amentoflavone Promotes Cellular Uptake and Degradation of Amyloid-Beta in Neuronal Cells
Byung Hee Han, Brooke Cofell, Emily Everhart, Courtney Humpal, Sam-Sik Kang, Sang Kook Lee, Jeong Sook Kim‐Han · 2022 · International Journal of Molecular Sciences
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Furong Gao, Jiefang Chen, Yuancun Zhou, Letong Cheng, Ming Hu, Xiaohui Wang · 2023 · RSC Medicinal Chemistry
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Priyanka Chauhan, S. Muralidharan, Anand Babu Velappan, Dhrubajyoti Datta, Sanjay Pratihar, Joy Debnath, Kalyan Sundar Ghosh · 2017 · JBIC Journal of Biological Inorganic Chemistry
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Chelation-induced diradical formation as an approach to modulation of the amyloid-β aggregation pathway
Meghan R. Porter, Akiko Kochi, Jonathan A. Karty, Mi Hee Lim, Jeffrey M. Zaleski · 2014 · Chemical Science
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Chin‐Lan Fu, Li‐Shin Hsu, Yung‐Feng Liao, Ming‐Kuan Hu · 2016 · Archiv der Pharmazie
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Mohsen Asadbegi, A. Shamloo · 2019 · ACS Chemical Neuroscience
Aryldiazoquinoline based multifunctional small molecules for modulating Aβ 42 aggregation and cholinesterase activity related to Alzheimer's disease
Monika Rana, Abhishek Pareek, Shivani Bhardwaj, Geeta Arya, Surendra Nimesh, Hemant Arya, Tarun Kumar Bhatt, Srinivasarao Yaragorla, Anuj K. Sharma · 2020 · RSC Advances
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Olga Olegovna Krasnovskaya, Daniil V. Spector, Alexander Zlobin · 2020 · International Journal of Molecular Sciences
2-(4-Hydroxyphenyl)benzothiazole dicarboxylate ester TACN chelators for 64 Cu PET imaging in Alzheimer's disease
Yujue Wang, Truc T. Huynh, Nilantha Bandara, Hong‐Jun Cho, Buck E. Rogers, Liviu M. Mirica · 2021 · Dalton Transactions
Identification of 2-subsituted benzothiazole derivatives as triple-functional agents with potential for AD therapy
Liu Jiang, Minkui Zhang, Li Tang, Qinjie Weng, Yanhong Shen, Yongzhou Hu, Rong Sheng · 2016 · RSC Advances
Synthesis and Evaluation of Novel Ligustrazine Derivatives as Multi-Targeted Inhibitors for the Treatment of Alzheimer’s Disease
Wenhao Wu, Xintong Liang, Guoquan Xie, Lang-di Chen, Weixiong Liu, Guolin Luo, Peiquan Zhang, Lihong Yu, Xuehua Zheng, Hong Ji et al. · 2018 · Molecules
A role for bioinorganic chemistry in the reactivation of mutant p53 in cancer
Jessica J. Miller, Kalvin Kwan, Christian Gaiddon, Tim Storr · 2022 · JBIC Journal of Biological Inorganic Chemistry
High-Affinity Fluorescent Probes for the Detection of Soluble and Insoluble Aβ Deposits in Alzheimer’s Disease
Rathnam Mallesh, Juhee Khan, Prabir Kumar Gharai, Subhajit Ghosh, Shubham Garg, Mohammad Umar Arshi, Surajit Ghosh · 2023 · ACS Chemical Neuroscience
Salen-based bifunctional chemosensor for copper (II) ions: Inhibition of copper-induced amyloid-β aggregation.
Hui-juan Yu, Wei Zhao, Yu Zhou, Gui-Juan Cheng, Ming Sun, Lu Wang, Lin Yu, Steven H. Liang, Chong-Zhao Ran · 2020 · Analytica Chimica Acta
Targeting misfolding and aggregation of the amyloid-β peptide and mutant p53 protein using multifunctional molecules
Lauryn Grcic, Grace Leech, Kalvin Kwan, Tim Storr · 2024 · Chemical Communications
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Yiran Huang, Truc T. Huynh, Liang Sun, Chi‐Herng Hu, Yung-Ching Wang, Buck E. Rogers, Liviu M. Mirica · 2022 · Inorganic Chemistry
Development of multifunctional heterocyclic Schiff base as a potential metal chelator: a comprehensive spectroscopic approach towards drug discovery
Manojkumar Jadhao, Chayan Das, Anoop Rawat, Himank Kumar, Ritika Joshi, Sudipta Maiti, Sujit Kumar Ghosh · 2016 · JBIC Journal of Biological Inorganic Chemistry
Bifunctional compounds targeting both D2 and non-α7 nACh receptors: Design, synthesis and pharmacological characterization
Carlo Matera, Luca Pucci, Chiara Fiorentini, Sergio Fucile, Cristina Missale, Giovanni Grazioso, Francesco Clementi, Michèle Zoli, Marco De Amici, Cecilia Gotti et al. · 2015 · European Journal of Medicinal Chemistry
Metallo-Biopolymers: Conjugation Strategies and Applications
Prakash Sista, Koushik Ghosh, Jennifer S. Martinez, Reginaldo C. Rocha · 2014 · Journal of macromolecular science. Part C, Reviews in macromolecular chemistry and physics/Journal of macromolecular science. Reviews in macromolecular chemistry and physics
Structure and mechanism behind the inhibitory effect of water soluble metalloporphyrins on Aβ 1–42 aggregation
Qianqian Zhang, Yiqing Liu, Jinming Wu · 2022 · Inorganic Chemistry Frontiers
Donepezil and Memantine Derivatives for Dual-Function and Prodrug Applications in Alzheimer’s Disease
Karna Terpstra, C. G. GUTIERREZ, Kai Gui, Liviu M. Mirica · 2025 · ACS Chemical Neuroscience
Design, synthesis, and evaluation of 2,2’-bipyridyl derivatives as bifunctional agents against Alzheimer’s disease
Ren‐Xian Tan, Weihao Li, Jia-Min Pang, Si-Min Zhong, Xin-Yi Huang, Jun-Ze Deng, Luyi Zhou, Jia‐Qiang Wu, Xiaoqin Wang · 2023 · Molecular Diversity
Molecular Insights into Cu/Zn Metal Response to the Amyloid β-Peptide (1–42)
Anurag Prakash Sunda, Anuj K. Sharma · 2023 · ACS Physical Chemistry Au
Spin state dependent peroxidase activity of heme bound amyloid β peptides relevant to Alzheimer's disease
Arnab Kumar Nath, Madhuparna Roy, Chinmay Dey, Abhishek Dey, Somdatta Ghosh Dey · 2022 · Chemical Science
Bifunctional Copper Chelators Capable of Reducing Aβ Aggregation and Aβ-Induced Oxidative Stress
Olga Olegovna Krasnovskaya, Daniil Abramchuk, Alexander N. Vaneev, Petr V. Gorelkin, Maxim A. Abakumov, Roman V. Timoshenko, Ilia Kuzmichev, Nelly S. Chmelyuk, Veronika V. Vadekhina, Regina M. Kuanaeva et al. · 2024 · ACS Omega
An electrochemiluminescent/colorimetric dual-mode biosensor for ultrasensitive detection of amyloid β based on Cu2+-g-C3N4 nanomaterials
Yingru Tang, Niankang Qiu, Lufei Pi · 2024 · Microchemical Journal
N,N′-1,10-Bis(Naringin) Triethylenetetraamine, Synthesis and as a Cu(II) Chelator for Alzheimer’s Disease Therapy
Lixia Guo, Bin Sun · 2020 · Biological and Pharmaceutical Bulletin
A new copper ionophore DPMQ protects cells against ultraviolet B irradiation by inhibiting the TRPV1 channel
Kuo‐Feng Huang, Kuo‐Hsing Ma, Yu‐Chien Hung, Liang‐Chuan Lo, Kuo‐Chen Lin, Pei‐Shan Liu, Ming‐Kuan Hu, Sheau‐Huei Chueh · 2018 · Journal of Cellular Physiology
Revisiting Cu(II) Bound Amyloid-β40 and Amyloid-β42 Peptides: Varying Coordination Chemistries
Orkid Coskuner‐Weber · 2018 · Journal of the Turkish Chemical Society Section A Chemistry
Metal Binding by GMP-1 and Its Pyrimido [1, 2]benzimidazole Analogs Confirms Protection Against Amyloid-β Associated Neurotoxicity
Rajnish Kumar, Pavel F. Pavlov, Bengt G. Winblad · 2019 · Journal of Alzheimer s Disease
Design, synthesis and comparison of water-soluble phthalocyanine/porphyrin analogues and their inhibition effects on Aβ 42 fibrillization
Weiyuan Xu, Chao Gao, Xinyang Sun, William Tai, Hong Lok Lung, Ga‐Lai Law · 2021 · Inorganic Chemistry Frontiers
Ligand Design to Target and Modulate Metal–Protein Interactions in Neurodegenerative Diseases
Michael W. Beck, Amit S. Pithadia, Alaina S. DeToma, Kyle J. Korshavn, Mi Hee Lim · 2014 · Wiley eBooks
Evaluation of Anti‐Alzheimer's Potential of Azo‐Stilbene‐Thioflavin‐T derived Multifunctional Molecules: Synthesis, Metal and Aβ Species Binding and Cholinesterase Activity
Monika Rana, Karna Terpstra, C. G. GUTIERREZ, Kerui Xu, Hemant Arya, Tarun Kumar Bhatt, Liviu M. Mirica, Anuj K. Sharma · 2024 · Chemistry - A European Journal
Turn-on fluorescent sensors for Cu-rich amyloid β peptide aggregates
Yiran Huang, Liang Sun, Liviu M. Mirica · 2022 · Sensors & Diagnostics
A multifunctional metal regulator as the potential theranostic agent: Design, synthesis, anti-AD activities and metallic ion sensing properties
Xiaodi Kou, Chengting Hu, Xuli Shi, Xingying Li, Ai‐Hong Yang, Rui Shen · 2022 · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy
A small bifunctional chelator that modulates Aβ42 aggregation
Chaofeng Zhang, Luiza Moreira Gomes, Tonglu Zhang, Tim Storr · 2017 · Canadian Journal of Chemistry
Rational Design of a Cu Chelator That Mitigates Cu‐Induced ROS Production by Amyloid Beta
Suchitra Mitra, Kallol Talukdar, Pallavi Prasad, Sandeep Kumar Misra, Shabana Iqrar Khan, Joshua S. Sharp, Jonah W. Jurss, Saumen Chakraborty · 2021 · ChemBioChem
Aβ-Targeting Bifunctional Chelators (BFCs) for Potential Therapeutic and PET Imaging Applications
Olga Olegovna Krasnovskaya, A. О. Kononova, Alexander S. Erofeev, Petr V. Gorelkin, Alexander G. Majouga, Elena Kimovna Beloglazkina · 2022 · International Journal of Molecular Sciences
Spectroscopic study on the interaction of Aβ42 with di(picolyl)amine derivatives and the toxicity to SH-S5Y5 cells
Meng-Yun Kong, Qiu‐Yun Chen, Ling Yao, Yin-Bing Wang · 2014 · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy
Griess’s Reagent-Based Azo Compounds Ameliorate Multifaceted Toxicity and Ferroptosis in Alzheimer’s Disease
Ashish Kumar, Tanmay Mondal, Madhu Ramesh, Jikesh Bhoi, Sourav Samanta, Thimmaiah Govindaraju · 2026 · ACS Chemical Neuroscience
Ultraviolet light triggers the conversion of Cu2+-bound Aβ42 aggregates into cytotoxic species in a copper chelation-independent manner
Xiongwei Dong, Zhe Zhang, Dan Yang Zhao, Yaojing Liu, Yan Meng, Yong Zhang, Dan Zhang, Changlin Liu · 2015 · Scientific Reports
Sialic Acid Hydroxamate: A Potential Antioxidant and Inhibitor of Metal‐Induced β‐Amyloid Aggregates
Rohan Yadav, Raghavendra Vasudeva Murthy, Raghavendra V Kikkeri · 2015 · ChemBioChem
Umbelliferyloxymethyl phosphonate compounds-weakly binding zinc ionophores with neuroprotective properties
Sébastien Guesné, Laura Connole, Stephanie Kim, Majid Motevalli, Lesley G. Robson, Adina Teodora Michael-Titus, Alice C. Sullivan · 2021 · Dalton Transactions
Hydrogen Exchange Mass Spectrometry for the Analysis of Ligand Binding and Protein Aggregation
Ying Zhang, Don L. Rempel, Michael L. Gross · 2016 · Wiley eBooks
Papaverine-Derived Dual-Active Modulator Ameliorates Alzheimer’s Disease Pathology in Aged APP/PSEN1 Transgenic Mice
Ashish Kumar, Madhu Ramesh, Jikesh Bhoi, Thimmaiah Govindaraju · 2025 · Journal of Medicinal Chemistry
Discovery of a Potent, Selective, and Blood-Brain Barrier Permeable Non-nitrocatechol Inhibitor of Catechol-O-methyltransferase
Sofia Benfeito, Bárbara Albuquerque, Lisa Sequeira, Carla Lima, Daniel Chavarria, Paula Serrão, Fernando Cagide, Patrı́cio Soares-da-Silva, Fernanda Borges · 2024 · Journal of Medicinal Chemistry
Lung nodules after whole lung radiation.
Mervyn D. Cohen, David L. Mirkin, Arthur J. Provisor, Ned B. Hornback, J A Smith, Robert D. Slabaugh · 1983 · PubMed
Metal Ions and Complexes in A lzheimer's Disease: From Fundamental to Therapeutic Perspectives
Christelle Hureau · 2018 · Wiley eBooks
An Electrochemistry and Computational Study at an Electrified Liquid–Liquid Interface for Studying Beta-Amyloid Aggregation
Bongiwe Silwane, Mark Richard Wilson, Ritu Kataky · 2023 · Membranes
2-Phenylbenzothiazolyl iridium complexes as inhibitors and probes of amyloid β aggregation
Karna Terpstra, Yiran Huang, Hanah Na, Liang Sun, Citlali Gutierrez, Zhengxin Yu, Liviu M. Mirica · 2024 · Dalton Transactions
Ruthenium Complexes of Phenylbenzothiazole‐Quinoline based Ligands for Selective α‐Olefination of Methylazaarenes
Surabhi Bhatt, Priyal Malpani, Swati Swornaprava Pati, Nitish Kumar, Nattamai S. P. Bhuvanesh, Hemant Joshi, Anuj K. Sharma · 2024 · European Journal of Inorganic Chemistry
Synthesis and bio-activities of bifunctional tetrahydrosalen Cu (II) chelators with potential efficacy in Alzheimer's disease therapy
Bin Sun, Heyan Jiang · 2024 · Journal of Inorganic Biochemistry
Ultraviolet irradiation-mediated formation of Aβ 42 oligomers and reactive oxygen species in Zn 2+ -bound Aβ 42 aggregates irrespective of the removal of Zn 2+
Xiang Li, Xiongwei Dong, Yaojing Liu, Yan Meng, Yong Zhang, Dan Zhang, Changlin Liu · 2016 · New Journal of Chemistry
Targeting Assembly and Disassembly of Protein Aggregates
Pierfausto Seneci · 2015 · Elsevier eBooks
Different Inhibitors of Aβ42-Induced Toxicity Have Distinct Metal-Ion Dependency
Ashley J Mason, Ian Hurst, Ravinder Malik, Ibrar Ahmed Siddique, Inna Solomonov, Irit Sagi, Frank‐Gerrit Klärner, Thomas H. Schrader, Gal Bitan · 2020 · ACS Chemical Neuroscience
Dexter Energy Transfer Photocatalytic Microdissection of Amyloid Plaques in Alzheimer’s Disease
Rui Xue Sun, Jintai Deng, Di Shen, Jian Yan, Yanan Huang, Huan Feng, Man Li, Yusong Ge, Xin Zhang, Yu Liu · 2026 · JACS Au
Zinc-porphyrin complex as multifunctional anti-AD agent: Synthesis, X-ray single crystal analysis and activity study
Xiang Zhou, Lijun Zhang, Jie Zhi, Lihua Zhao, Rui Shen, Aihong Yang, Xiaodi Kou · 2026 · Journal of Inorganic Biochemistry
Exploring Flavonoids Rutin and Morin as Multi‐Target–Directed Ligands for Metal Chelation, Amyloid Interaction, and AChE‐Induced Amyloid Inhibition
Priyal Malpani, Monika Rana, Umesh Morda, Anuj K. Sharma · 2026 · ChemistrySelect
Aβ-affine bifunctional copper chelators capable of Aβ-induced oxidative stress reduction and amyloid disaggregation
Olga Olegovna Krasnovskaya, Daniil Abramchuk, Alexander N. Vaneev, Petr V. Gorelkin, Maxim A. Abakumov, Roman V. Timoshenko, Nelly S. Chmelyuk, Veronika V. Vadekhina, Regina M. Kuanaeva, Evgeniy V. Dubrovin et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
Combining BACE1 Inhibition with Metal Chelation as Possible Therapy for Alzheimer’s Disease
Maged Henary, Tyler L. Dost, Eric A. Owens, Surendra Reddy Punganuru · 2014 · Elsevier eBooks
Myco-Nanoparticles: A Novel Approach for Inhibiting Amyloid-β Fibrillation
Aditya Saran, Rajender Boddula, Priyanka Dubey, Ramyakrishna Pothu, Saurabh Gautam · 2018 · Nanotechnology in the life sciences
Unveiling the Light Induced Energy Transfer Events in Water Soluble Benzothiazole Appended Borondipyrromethene: Synthesis, Photophysical Study, and Applications to Amyloid Binding
Srikanth Bandi, RMH Rathnayaka, Monika Rana, Akanksha Ashok Sangolkar, Ghida Fawaz, Esha Gahunia, Amandine Courtemanche, Anjaiah Boligorla, Ravinder Pawar, Anuj K. Sharma et al. · 2025 · Chemistry - An Asian Journal