The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Oxidative Cleavage of Cellulose by Fungal Copper-Dependent Polysaccharide Monooxygenases
Abstract
Fungal-derived, copper-dependent polysaccharide monooxygenases (PMOs), formerly known as GH61 proteins, have recently been shown to catalyze the O(2)-dependent oxidative cleavage of recalcitrant polysaccharides. Different PMOs isolated from Neurospora crassa were found to generate oxidized cellodextrins modified at the reducing or nonreducing ends upon incubation with cellulose and cellobiose dehydrogenase. Here we show that the nonreducing end product formed by an N. crassa PMO is a 4-ketoaldose. Together with isotope labeling experiments, further support is provided for a mechanism involving oxygen insertion and subsequent elimination to break glycosidic bonds in crystalline cellulose.
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Cites
US Department of Energy (USDOE), W., Perlack, R., USDOE Office of Energy Efficiency and Renewable Energy (EERE), O. O. S. T. B. T. O. (., Oak Ridge National Laboratory (ORNL), O. R., USDA, Wright, L., Turhollow, A., Graham, R., Stokes, B., & Erbach, D. (2005) · doi:10.2172/1216415 · Cited by 1,327
Cited by
O'Connell, R. J., Thon, M. R., Hacquard, S., Amyotte, S. G., Kleemann, J., Torres, M. F., Damm, U., Buiate, E. A., Epstein, L., Alkan, N., et al. (2012) · Nature Genetics · doi:10.1038/ng.2372 · Cited by 1,047
Payne, C. M., Knott, B. C., Mayes, H. B., Hansson, H., Himmel, M. E., Sandgren, M., Ståhlberg, J., & Beckham, G. T. (2015) · Chemical Reviews · doi:10.1021/cr500351c · Cited by 855
Oxidative cleavage of polysaccharides by monocopper enzymes depends on H2O2
Bissaro, B., Røhr, Å. K., Müller, G., Chylenski, P., Skaugen, M., Forsberg, Z., Horn, S. J., Vaaje-Kolstad, G., & Eijsink, V. G. H. (2017) · Nature Chemical Biology · doi:10.1038/nchembio.2470 · Cited by 594
Lytic Polysaccharide Monooxygenases in Biomass Conversion
Hemsworth, G. R., Johnston, E. M., Davies, G. J., & Walton, P. H. (2015) · Trends in Biotechnology · doi:10.1016/j.tibtech.2015.09.006 · Cited by 314
Enzymatic upgrading of nanochitin using an ancient lytic polysaccharide monooxygenase
(2022) · doi:10.1038/s43246-022-00277-9 · Cited by 16
Metadata
- Authors
- Beeson, W. T., Phillips, C. M., Cate, J. H. D., & Marletta, M. A.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2011-12-28
- Volume
- 134
- Issue
- 2
- Pages
- 890-892
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W1995038206
- Cited by
- 465
- References
- 1
- FWCI
- 18.96
- Type
- journal article
- Language
- en
- Open access
- closed
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- Beeson, W. T., Phillips, C. M., Cate, J. H. D., & Marletta, M. A. (2012). Oxidative Cleavage of Cellulose by Fungal Copper-Dependent Polysaccharide Monooxygenases. Journal of the American Chemical Society. https://doi.org/10.1021/ja210657t
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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