Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models

Skouta, Rachid, Dixon, Scott J., Wang, Jianlin, Dunn, Denise E., Orman, Marina, Shimada, Kenichi, Rosenberg, Paul A., Lo, Donald C. +3 more·2014·Journal of the American Chemical Society
DOI 10.1021/ja411006a

Cited by (1,001)

Items 401–500 of 1,001

  1. Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached
    Daniel J. Wilcock, Andrew P. Badrock, Chun Wai Wong, Rhys Owen, Melissa Guerin, Andrew D. Southam, Hannah R. Johnston, Brian A. Telfer, Paul Fullwood, Joanne Watson et al. · 2022 · Cell Reports
  2. Ferroptosis in tumor immunity and therapy
    Chuandong Gong, Qiankun Ji, Miaojing Wu, Zewei Tu, Kunjian Lei, Min Luo, Junzhe Liu, Li Lin, Kuangxun Li, Jingying Li et al. · 2022 · Journal of Cellular and Molecular Medicine
  3. Biological and Catalytic Properties of Selenoproteins
    Jean Chaudière · 2023 · International Journal of Molecular Sciences
  4. Ferroptosis Is Regulated by Mitochondria in Neurodegenerative Diseases
    Jue-Pu Zhou, Yao Jin, Yu-Hong Lei, Tianyi Liu, Zheng Wan, Hao Meng, Honglei Wang · 2020 · Neurodegenerative Diseases
  5. Chemically Induced Models of Parkinson’s Disease: History and Perspectives for the Involvement of Ferroptosis
    Shuheng Wen, Toshihiko Aki, Kana Unuma, Koichi Uemura · 2020 · Frontiers in Cellular Neuroscience
  6. Paeoniflorin alleviates ischemia/reperfusion induced acute kidney injury by inhibiting Slc7a11-mediated ferroptosis
    Lijuan Ma, Xueqi Liu, Mengya Zhang, Lang Zhou, Ling Jiang, Li Gao, Xian Wang, Yuebo Huang, Han-xu Zeng, Yonggui Wu · 2023 · International Immunopharmacology
  7. Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis In Vivo
    John T. Randolph, Matthew J. O’Connor, Fei Han, Charles W. Hutchins, Y. Amy Siu, Min Y. Cho, Yunan Zheng, Jonathan A. Hickson, Jana L. Markley, Vlasios Manaves et al. · 2023 · Journal of Medicinal Chemistry
  8. Ferroptosis and Neurodegenerative Diseases: Insights into the Regulatory Roles of SLC7A11
    Chen Wang, Haihui Liu, Si Xu, Yu Lin Deng, Bin Xu, Tianyao Yang, Wei Liu · 2023 · Cellular and Molecular Neurobiology
  9. Ferroptosis in hepatic ischemia‑reperfusion injury: Regulatory mechanisms and new methods for therapy (Review)
    Linfeng Luo, Guoheng Mo, Deqiang Huang · 2021 · Molecular Medicine Reports
  10. Cycloacceleration of Reactive Oxygen Species Generation Based on Exceedingly Small Magnetic Iron Oxide Nanoparticles for Tumor Ferroptosis Therapy
    Huimin Zhou, Xuanyi Lu, Chao Du, Zijian Zhou, Jie Feng, Zhiyu Liang, Yikai Xu, Xiaozhong Qiu, Zheyu Shen · 2022 · Small
  11. AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells
    Kaitlyn M. Cahuzac, Abigail Lubin, Kaitlyn N. Bosch, Nicole Stokes, Sarah Schoenfeld, Royce W. Zhou, Haddy Lemon, John M. Asara, Ramon E. Parsons · 2023 · Cell Reports
  12. Abnormal Ferroptosis in Myelodysplastic Syndrome
    Qi Lv, Haiyue Niu, Lanzhu Yue, Jiaxi Liu, Liyan Yang, Chunyan Liu, Huijuan Jiang, Shuwen Dong, Zonghong Shao, Limin Xing et al. · 2020 · Frontiers in Oncology
  13. Ferroptosis in cardiac hypertrophy and heart failure
    Kuo Zhang, Xin-Miao Tian, Wei Li, Liying Hao · 2023 · Biomedicine & Pharmacotherapy
  14. Role of ferroptosis in chronic kidney disease
    Shiyang Li, Qiuxia Han, Chang Liu, Yixue Wang, Fengxun Liu, Shaokang Pan, Lihua Zuo, Dan Gao, Kai Chen, Qi Feng et al. · 2024 · Cell Communication and Signaling
  15. Insight into Iron, Oxidative Stress and Ferroptosis: Therapy Targets for Approaching Anticancer Strategies
    Marialuisa Piccolo, Maria Grazia Ferraro, Federica Iazzetti, Rita Santamaria, Carlo Irace · 2024 · Cancers
  16. Ferroptosis Contributes to Isoflurane Neurotoxicity
    Yimeng Xia, Xiaoyun Sun, Yan Luo, Creed M. Stary · 2019 · Frontiers in Molecular Neuroscience
  17. Redox Balance Keepers and Possible Cell Functions Managed by Redox Homeostasis in Trypanosoma cruzi
    Andrea C. Mesías, Nisha Jain Garg, Maria Paola Zago · 2019 · Frontiers in Cellular and Infection Microbiology
  18. Ether lipid deficiency disrupts lipid homeostasis leading to ferroptosis sensitivity
    Marcos A. Perez, Andrea J. Clostio, Isabel R. Houston, Jimena Ruiz, Leslie Magtanong, Scott J. Dixon, Jennifer L. Watts · 2022 · PLoS Genetics
  19. IRF1/ZNF350/GPX4-mediated ferroptosis of renal tubular epithelial cells promote chronic renal allograft interstitial fibrosis
    Yao Zhang, Jianjian Zhang, Dengyuan Feng, Hai Zhou, Zeping Gui, Ming Zheng, Zhou Hang, Zijie Wang, Zengjun Wang, Min Jeong Gu et al. · 2022 · Free Radical Biology and Medicine
  20. Induction Mechanism of Ferroptosis, Necroptosis, and Pyroptosis: A Novel Therapeutic Target in Nervous System Diseases
    Lu Tang, Sitong Liu, Shiwei Li, Ye Chen, Bingqing Xie, Jun F. Zhou · 2023 · International Journal of Molecular Sciences
  21. Ferroptosis mechanism and Alzheimer's disease
    Lina Feng, Jingyi Jenny Sun, Ling Xia, Qiang Shi, Ya‐Jun Hou, Lili Zhang, Mingquan Li, Cundong Fan, Bao‐liang Sun · 2023 · Neural Regeneration Research
  22. The role of glutathione peroxidase 4 in neuronal ferroptosis and its therapeutic potential in ischemic and hemorrhagic stroke
    Chao Wei · 2024 · Brain Research Bulletin
  23. Ferrostatin-1 alleviates cerebral ischemia/reperfusion injury through activation of the AKT/GSK3β signaling pathway
    Xinyao Liu, Yue Du, Jian Liu, Linggang Cheng, Wen He, Wei Zhang · 2022 · Brain Research Bulletin
  24. Iron overload and altered iron metabolism in ovarian cancer
    Stephanie Rockfield, Joseph Raffel, Radhe Mehta, Nabila Rehman, Meera Nanjundan · 2017 · Biological Chemistry
  25. iTRAQ-based quantitative proteomics reveals a ferroptosis-like programmed cell death in plants infected by a highly virulent tobacco mosaic virus mutant 24A+UPD
    Mercy Wairimu Macharia, Prem Prakash Das, Naweed I. Naqvi, Sek‐Man Wong · 2020 · Phytopathology Research
  26. Silica Nanoparticles Cause Activation of NLRP3 Inflammasome in-vitro Model-Using Microglia
    Shanshan Hou, Chao Li, Yihua Wang, Jiayin Sun, Yutong Guo, Xiaofan Ning, Kai Ma, Xinyue Li, Hua Shao, Guanqun Cui et al. · 2022 · International Journal of Nanomedicine
  27. Cysteine preservation confers resistance to glutathione-depleted cells against ferroptosis via CDGSH iron sulphur domain-containing proteins (CISDs)
    Takujiro Homma, Sho Kobayashi, Junichi Fujii · 2020 · Free Radical Research
  28. Insight into the potential role of ferroptosis in neurodegenerative diseases
    Yingying Ji, Kai Zheng, Shiming Li, Caili Ren, Ying Shen, Lin Tian, Haohao Zhu, Zhenhe Zhou, Ying Jiang · 2022 · Frontiers in Cellular Neuroscience
  29. Protective effect of curcumin on hepatolenticular degeneration through copper excretion and inhibition of ferroptosis
    Xun Sun, Xinyu Zhang, Hui Yan, Hongfei Wu, Shijian Cao, Wenchen Zhao, Ting Dong, An Zhou · 2022 · Phytomedicine
  30. Targeting Ferroptosis in Parkinson’s Disease: Mechanisms and Emerging Therapeutic Strategies
    Minghao Zhou, Keyang Xu, Jianxian Ge, Xingnian Luo, Mengyao Wu, Ning Wang, Jianfeng Zeng · 2024 · International Journal of Molecular Sciences
  31. Iron, Oxidative Damage and Ferroptosis in Rhabdomyosarcoma
    Alessandro Fanzani, Maura Poli · 2017 · International Journal of Molecular Sciences
  32. Palladium‐Catalyzed Synthesis of N‐Cyclohexyl Anilines from Phenols with Hydrazine or Hydroxylamine via N‐N/O Cleavage
    Jiang‐Sheng Li, Zihang Qiu, C.‐J. LI · 2017 · Advanced Synthesis & Catalysis
  33. Cell Death Pathways Drive Necroinflammation during Acute Kidney Injury
    Anne von Mäßenhausen, Wulf Tonnus, Andreas Linkermann · 2018 · The Nephron journals/Nephron journals
  34. Ferroptosis induces detrimental effects in chronic EAE and its implications for progressive MS
    Jhelum, Priya, Zandee, Stephanie, Ryan, Fari, Zarruk, Juan G., Michalke, Bernhard, Venkataramani, Vivek, Curran, Laura, Klement, Wendy, Prat, Alexandre, David, Samuel · 2023 · Acta Neuropathologica Communications
  35. Nucleotide biosynthesis links glutathione metabolism to ferroptosis sensitivity
    Amy Tarangelo, Jason Rodencal, Joon T. Kim, Leslie Magtanong, Jonathan Z. Long, Scott J. Dixon · 2022 · Life Science Alliance
  36. Hypertoxic self-assembled peptide with dual functions of glutathione depletion and biosynthesis inhibition for selective tumor ferroptosis and pyroptosis
    Yang Gao, Yun Li, Hongmei Cao, Haixue Jia, Dianyu Wang, Chunhua Ren, Zhongyan Wang, Cuihong Yang, Jianfeng Liu · 2022 · Journal of Nanobiotechnology
  37. Induction of ferroptosis by HO-1 contributes to retinal degeneration in mice with defective clearance of all-trans-retinal
    Chao Chen, Kunhuan Yang, Danxue He, Bo Yang, Lei Tao, Jingmeng Chen, Yalin Wu · 2022 · Free Radical Biology and Medicine
  38. Neutrophil membrane-based biomimetic metal-polyphenol self-assembled nanozyme for the targeting treatment of early brain injury following subarachnoid hemorrhage
    Wei Huang, Yu Tian, Jing Ma, Penghui Wei, Chengzhong Du, Xiaodan Zhang, Fuxiang Chen, Yuanxiang Lin, Yang Zhu, Dezhi Kang · 2024 · Chemical Engineering Journal
  39. Regulated Cell Death Seen through the Lens of Islet Transplantation
    Antônio de Castro Bruni, Stefan Richard Bornstein, Andreas Linkermann, A. M. James Shapiro · 2018 · Cell Transplantation
  40. GPX4: old lessons, new features
    Thamara Nishida Xavier da Silva, José Pedro Friedmann Angeli, Irina Ingold · 2022 · Biochemical Society Transactions
  41. Ferritinophagy in the etiopathogenic mechanism of related diseases
    Xuemei Jin, Chunjie Jiang, Zhizhou Zou, He Huang, Xiaojian Li, Songji Xu, Rongshao Tan · 2023 · The Journal of Nutritional Biochemistry
  42. A targetable PRR11-DHODH axis drives ferroptosis- and temozolomide-resistance in glioblastoma
    Zong Miao, Lei Xu, Wei Jun Gu, Yimin Ren, Rong Li, Shuai Zhang, Chao Chen, Hongxiang Wang, Jing Ji, Juxiang Chen · 2024 · Redox Biology
  43. Designing an ESIPT-based fluorescent probe for imaging of hydrogen peroxide during the ferroptosis process
    Han-Chen Zhang, Dihua Tian, Ya-Long Zheng, Fang Dai, Bo Zhou · 2020 · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy
  44. MiR-378a-3p/ SLC7A11 regulate ferroptosis in nerve injury induced by lead exposure
    Wang, Weixuan, Shi, Fan, Cui, Jianmei, Pang, Shulan, Zheng, Gang, Zhang, Yanshu · 2022 · Ecotoxicology and Environmental Safety
  45. Systems biology of ferroptosis: A modeling approach
    Anna Konstorum, Lia Tesfay, Bibbin T. Paul, Frank M. Torti, Reinhard Laubenbacher, Suzy V. Torti · 2020 · Journal of Theoretical Biology
  46. Adipocyte GPX4 protects against inflammation, hepatic insulin resistance and metabolic dysregulation
    Julian Schwärzler, Lisa Mayr, Bernhard Radlinger, Felix Grabherr, Maureen Philipp, Bernhard Texler, Christoph Grander, Andreas Ritsch, Monika Hunjadi, Barbara Enrich et al. · 2022 · International Journal of Obesity
  47. Structure-activity relationship study of RSL3-based GPX4 degraders and its potential noncovalent optimization
    Cangxin Zheng, Chao Wang, Dan Sun, Han Wang, Bingru Li, Guoquan Liu, Zhenming Liu, Liangren Zhang, Ping Xu · 2023 · European Journal of Medicinal Chemistry
  48. Regulated cell death pathways in the sodium iodate model: Insights and implications for AMD
    Mala Upadhyay, Vera L. Bonilha · 2023 · Experimental Eye Research
  49. Ferroptosis-based advanced therapies as treatment approaches for metabolic and cardiovascular diseases
    Francesca Maremonti, Wulf Tonnus, Shubhangi Gavali, Stefan Richard Bornstein, Ajay M. Shah, Mauro Giacca, Andreas Linkermann · 2024 · Cell Death and Differentiation
  50. Ferroptosis: a novel cell death form will be a promising therapy target for diseases
    Di Wu, Linxi Chen · 2015 · Acta Biochimica et Biophysica Sinica
  51. Targeting oxidative stress, a crucial challenge in renal transplantation outcome
    Romain Carcy, Marc Cougnon, Mallorie Poët, Manon Durandy, Antoine Sicard, Laurent Counillon, Nicolas Blondeau, Thierry Hauet, Michel Tauc, Didier F. Pisani · 2021 · Free Radical Biology and Medicine
  52. Silencing of PTPN18 Induced Ferroptosis in Endometrial Cancer Cells Through p-P38-Mediated GPX4/xCT Down-Regulation
    Haibo Wang, Siyuan Peng, Junhong Cai, Shan Bao · 2021 · Cancer Management and Research
  53. Long non-coding RNA ADAMTS9-AS1 attenuates ferroptosis by Targeting microRNA-587/solute carrier family 7 member 11 axis in epithelial ovarian cancer
    Cai Li, Xiaoqing Hu, Ye Lu, Pingjuan Bai, Youkun Jie, Kuanyong Shu · 2022 · Bioengineered
  54. Ferroptosis contributes to endometrial fibrosis in intrauterine adhesions
    Qi Zhu, Simin Yao, Ziying Ye, Peipei Jiang, Huiyan Wang, Xiwen Zhang, Dan Liu, Haining Lv, Chenrui Cao, Zhenhua Zhou et al. · 2023 · Free Radical Biology and Medicine
  55. Impact of ferroptosis on preeclampsia: A review
    Yuping Shan, Chengcheng Guan, Jingli Wang, Weihong Qi, Aiping Chen, Shiguo Liu · 2023 · Biomedicine & Pharmacotherapy
  56. Targeting ferroptosis in melanoma: cancer therapeutics
    Khatereh Khorsandi, HomaSadat Esfahani, Saeedeh Keyvani‐Ghamsari, Parisa lakhshehei · 2023 · Cell Communication and Signaling
  57. Metal-polyphenol self-assembled nanodots for NIR-II fluorescence imaging-guided chemodynamic/photodynamic therapy-amplified ferroptosis
    Yang Zhu, Chengyu Ding, Wenhua Fang, Tuanwei Li, Lingjun Yan, Yu Qing Tian, Wei Huang, Penghui Wei, Jing Ma, Xin Lin et al. · 2024 · Acta Biomaterialia
  58. Assessing the Antioxidant Properties of Larrea tridentata Extract as a Potential Molecular Therapy against Oxidative Stress
    Rachid Skouta, Karla Morán-Santibañez, Carlos A. Valenzuela, Abimael H Vasquez, Karine Fénelon · 2018 · Molecules
  59. Neutrophil metabolomics in severe COVID-19 reveal GAPDH as a suppressor of neutrophil extracellular trap formation
    Yafeng Li, Jessica S. Hook, Ding Qing, Xue Xiao, Stephen S. Chung, Marcel Mettlen, Lin Xu, Jessica G. Moreland, Michalis Agathocleous · 2023 · Nature Communications
  60. Redox (phospho)lipidomics of signaling in inflammation and programmed cell death
    Yulia Y. Tyurina, Claudette M. St. Croix, Simon C. Watkins, Alan M. Watson, Michael W. Epperly, Tamil S. Anthonymuthu, Elena R. Kisin, Irina I. Vlasova, Olga Krysko, Dmitri V. Krysko et al. · 2019 · Journal of Leukocyte Biology
  61. Beclin1-mediated ferroptosis activation is associated with isoflurane-induced toxicity in SH-SY5Y neuroblastoma cells
    Ruizhu Liu, Xuefeng Li, Guoqing Zhao · 2019 · Acta Biochimica et Biophysica Sinica
  62. PRDX6-mediated pulmonary artery endothelial cell ferroptosis contributes to monocrotaline-induced pulmonary hypertension
    Juan Liao, Shanshan Xie, Yan Deng, Dandan Wu, Hui Meng, Wei‐Fang Lan, Ping Dai · 2022 · Microvascular Research
  63. Targeting ferroptosis in neuroimmune and neurodegenerative disorders for the development of novel therapeutics.
    Zi-Hao Li, Ye Zhang, Mei-Ling Ji, Cheng-Long Wu, Yan-Xing Zhang, Senlin Ji · 2024 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  64. The clinical relevance of necroinflammation—highlighting the importance of acute kidney injury and the adrenal glands
    Wulf Tonnus, Florian Gembardt, Markus Latk, Simon Paul Parmentier, Christian Hugo, Stefan Richard Bornstein, Andreas Linkermann · 2018 · Cell Death and Differentiation
  65. Ferroptosis in Low-Grade Glioma: A New Marker for Diagnosis and Prognosis
    Yan Liu, Zhennan Xu, Tao Jin, Ke Xu, Mingfa Liu, Haixiong Xu · 2020 · Medical Science Monitor
  66. The role of ferroptosis in neurodegenerative diseases
    Yunfei Xu, Jie Zhao, Yao Zhao, Lin Zhou, Haoduo Qiao, Qing Xu, Ying Liu · 2022 · Molecular Biology Reports
  67. Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis
    Tian, Ruilin, Abarientos, Anthony, Hong, Jason, Hashemi, Sayed Hadi, Yan, Rui, Dräger, Nina, Leng, Kun, Nalls, Mike A., Singleton, Andrew B., Xu, Ke et al. · 2020
  68. Ferroptosis in Neurological Disease
    Samuel David, Fari Ryan, Priya Jhelum, Antje Kroner · 2022 · The Neuroscientist
  69. Lipid peroxidation of immune cells in cancer
    Liuling Xiao, Miao Xian, Chuanchao Zhang, Qi Guo, Qing Yi · 2024 · Frontiers in Immunology
  70. Down-regulation of Glutathione Peroxidase 4 in Oral Cancer Inhibits Tumor Growth Through SREBP1 Signaling
    Masakatsu Fukuda, Yudai Ogasawara, Hiroyasu Hayashi, Ayako Okuyama, Junya Shiono, Katsuyuki Inoue, Hideaki Sakashita · 2021 · Anticancer Research
  71. Ferroptosis promotes microtubule-associated protein tau aggregation via GSK-3β activation and proteasome inhibition
    Shaohui Wang, Yao Xing Jiang, Yabo Liu, Qianhui Liu, Hongwei Sun, Mengjie Mei, Xiaomei Liao · 2022 · Molecular Neurobiology
  72. Novel druggable mechanism of Parkinson's disease: Potential therapeutics and underlying pathogenesis based on ferroptosis
    Xiaoying Jiang, Kaiyu Wu, Xiang‐Yang Ye, Tian Xie, Pengfei Zhang, Benjamin E. Blass, Renren Bai · 2023 · Medicinal Research Reviews
  73. Endoplasmic Reticulum-Targeting Quinazolinone-Based Lipophilic Probe for Specific Photoinduced Ferroptosis and Its Induced Lipid Dynamic Regulation
    Zhiming Xing, Jiangyu Yan, Yongxiang Miao, Yawen Ruan, Haojun Yao, Youkang Zhou, Yingqun Tang, Guorui Li, Zhibin Song, Yiyuan Peng et al. · 2024 · Journal of Medicinal Chemistry
  74. Polyunsaturated fatty acids-induced ferroptosis suppresses pancreatic cancer growth
    Akane Suda, Banlanjo Abdulaziz Umaru, Yui Yamamoto, Hiroki Shima, Yuriko Saiki, Yijun Pan, Liang Jin, Jiaqi Sun, Yi Ling Low, Chitose Suzuki et al. · 2024 · Scientific Reports
  75. How does ferrocene correlate with ferroptosis? Multiple approaches to explore ferrocene-appended GPX4 inhibitors as anticancer agents
    Wei Li, Jing Xia Yu, Jing Wang, Xuejing Fan, Ximing Xu, Hui Wang, Ying Xiong, Xinyu Li, Xiaomin Zhang, Qianer Zhang et al. · 2024 · Chemical Science
  76. GPX4 restricts ferroptosis of NKp46+ILC3s to control intestinal inflammation
    Xinyao Li, Junyu He, Xiang Gao, Guilang Zheng, Chunling Chen, Yimin Chen, Zhe Xing, Tianci Wang, Jian Tang, Yuxiong Guo et al. · 2024 · Cell Death and Disease
  77. Green barley mitigates cytotoxicity in human lymphocytes undergoing aggressive oxidative stress, via activation of both the Lyn/PI3K/Akt and MAPK/ERK pathways
    Blanca Estela Ruiz-Medina, Dennise Lerma, Michael J. Hwang, Jeremy A. Ross, Rachid Skouta, Renato J. Aguilera, Robert Arthur Kirken, Armando Varela-Ramı́rez, Elisa Robles‐Escajeda · 2019 · Scientific Reports
  78. Research mechanisms of and pharmaceutical treatments for ferroptosis in liver diseases
    Jun Ge Yu, Jianqing Wang · 2020 · Biochimie
  79. Ferroptosis—A Novel Mechanism With Multifaceted Actions on Stroke
    Xiaoling Fang, Shao-Yun Ding, Xiaozheng Du, Jin-Hai Wang, Xinglan Li · 2022 · Frontiers in Neurology
  80. Materno-fetal iron transfer and the emerging role of ferroptosis pathways
    Jonas Zaugg, Fabia Solenthaler, Christiane Albrecht · 2022 · Biochemical Pharmacology
  81. Ferritin confers protection against iron-mediated neurotoxicity and ferroptosis through iron chelating mechanisms in MPP+-induced MES23.5 dopaminergic cells
    Na Zhang, Xiao‐Qi Yu, Limei Song, Zhixin Xiao, Junxia Xie, Huamin Xu · 2022 · Free Radical Biology and Medicine
  82. Discovery of novel diphenylbutene derivative ferroptosis inhibitors as neuroprotective agents
    Yuying Fang, Qingyun Tan, Huihao Zhou, Qiong Gu, Jun Xu · 2022 · European Journal of Medicinal Chemistry
  83. mTORC1 beyond anabolic metabolism: Regulation of cell death
    Jiajun Zhu, Hua Wang, Xuejun Jiang · 2022 · The Journal of Cell Biology
  84. Iron-responsive-like elements and neurodegenerative ferroptosis
    Jack T. Rogers, Catherine M. Cahill · 2020 · Learning & Memory
  85. Peroxiredoxin 6 suppresses ferroptosis in lung endothelial cells
    Julia María Torres-Velarde, Kaitlin N. Allen, Andrea Salvador‐Pascual, Roberto G. Leija, Diamond Luong, Diana D. Moreno-Santillán, David C. Ensminger, José Pablo Vázquez‐Medina · 2024 · Free Radical Biology and Medicine
  86. Functional role of ferroptosis on cancers, activation and deactivation by various therapeutic candidates-an update
    The Hong Phong Nguyen, B. Mahalakshmi, Bharath Kumar Velmurugan · 2019 · Chemico-Biological Interactions
  87. Ferroptosis-Related Genes in Neurodevelopment and Central Nervous System
    Soo-Whee Kim, Soo-Whee Kim, Yu-Jin Kim, Joon‐Yong An · 2021 · Biology
  88. Ferroptosis: A new insight for treatment of acute kidney injury
    Shiyang Li, Rui Wang, Yixue Wang, Yong Liu, Yingjin Qiao, Peipei Li, Jingfang Chen, Shaokang Pan, Qi Feng, Zhangsuo Liu et al. · 2022 · Frontiers in Pharmacology
  89. Iron as a therapeutic target in chronic liver disease
    Elias Kouroumalis, Ioannis Tsomidis, Argyro Voumvouraki · 2023 · World Journal of Gastroenterology
  90. Ferroptosis: Emerging Role in Diseases and Potential Implication of Bioactive Compounds
    Giuseppe Tancredi Patanè, Stefano Putaggio, Ester Tellone, Davide Barreca, Silvana Ficarra, Carlo Maffei, Antonella Calderaro, Giuseppina Laganà · 2023 · International Journal of Molecular Sciences
  91. Fisetin suppresses ferroptosis through Nrf2 and attenuates intervertebral disc degeneration in rats
    Chenchao Li, Yekai Zhang, Yuxin Deng, Yu Chen, Chenyu Wu, Xiaoying Zhao, Ximiao Chen, Xiangyang Wang, Yifei Zhou, Xiaolei Zhang et al. · 2023 · European Journal of Pharmacology
  92. Human proximal tubular epithelial cell-derived small extracellular vesicles mediate synchronized tubular ferroptosis in hypoxic kidney injury
    Xiangju Wang, Chang Seong Kim, Benjamin C. Adams, Ray Wilkinson, Michelle Mei Chih Hill, Alok Kishorkumar Shah, Ahmed Mohamed, Mriga Dutt, Monica Suet Ying Ng, Jacobus P J Ungerer et al. · 2024 · Redox Biology
  93. Role of mitochondrial reactive oxygen species in chemically-induced ferroptosis
    Xiuhan Song, Xiangyu Hao, Bao Ting Zhu · 2024 · Free Radical Biology and Medicine
  94. Parkinson Disease Signaling Pathways, Molecular Mechanisms, and Potential Therapeutic Strategies: A Comprehensive Review
    M. S. Khan, Somayyeh Nasiripour, Jean C. Bopassa · 2025 · International Journal of Molecular Sciences
  95. Ferroptosis in Cancer and Inflammatory Diseases: Mechanisms and Therapeutic Implications
    Guangyi Shen, Jiachen Liu, Yinhuai Wang, Zebin Deng, Fei Deng · 2025 · MedComm
  96. Insight Into the Role of Ferroptosis in Non-neoplastic Neurological Diseases
    Jianwei Lei, Zhihua Chen, Shuxin Song, Chunpeng Sheng, Sihui Song, Jianming Zhu · 2020 · Frontiers in Cellular Neuroscience
  97. A new role of glutathione peroxidase 4 during human erythroblast enucleation
    Hakim Ouled‐Haddou, Kahia Messaoudi, Yohann Demont, Rogério Lopes Dos Santos, Candice Carola, Alexis Caulier, Pascal Vong, Nicolas Jankovsky, Delphine Lebon, Alexandre Willaume et al. · 2020 · Blood Advances
  98. Tetramethyl bisphenol a inhibits leydig cell function in late puberty by inducing ferroptosis
    Dichao Hu, Lili Tian, Xueyun Li, Yirui Chen, Zheqing Xu, Ren‐Shan Ge, Yiyan Wang · 2022 · Ecotoxicology and Environmental Safety
  99. Targeting ferroptosis for leukemia therapy: exploring novel strategies from its mechanisms and role in leukemia based on nanotechnology
    Muhammad Hossein Ashoub, Razieh Razavi, Kamran Heydaryan, Masoud Salavati‐Niasari, Mahnaz Amiri · 2024 · European journal of medical research
  100. Molecular hydrogen suppresses free-radical-induced cell death by mitigating fatty acid peroxidation and mitochondrial dysfunction
    Katsuya Iuchi, Kiyomi Nishimaki, Naomi Kamimura, Shigeo Ohta · 2019 · Canadian Journal of Physiology and Pharmacology