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Enantioselective Conjugate Additions of α-Amino Radicals via Cooperative Photoredox and Lewis Acid Catalysis
Open accessAbstract
We report the highly enantioselective addition of photogenerated α-amino radicals to Michael acceptors. This method features a dual-catalyst protocol that combines transition metal photoredox catalysis with chiral Lewis acid catalysis. The combination of these two powerful modes of catalysis provides an effective, general strategy to generate and control the reactivity of photogenerated reactive intermediates.
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Citations
Cites
Asymmetric photochemical reactions in solution
Inoue, Y. (1992) · Chemical Reviews · doi:10.1021/cr00013a001 · Cited by 657
Cited by
Nakajima, K., Miyake, Y., & Nishibayashi, Y. (2016) · Accounts of Chemical Research · doi:10.1021/acs.accounts.6b00251 · Cited by 435
Metadata
- Authors
- Ruiz Espelt, L., McPherson, I. S., Wiensch, E. M., & Yoon, T. P.
- Venue
- Journal of the American Chemical Society
- Publisher
- American Chemical Society (ACS)
- Published
- 2015-02-16
- Volume
- 137
- Issue
- 7
- Pages
- 2452-2455
- ISSN
- 0002-7863 (ISSN-L)
- 1520-5126
- OpenAlex
- W2316173449
- Cited by
- 310
- References
- 1
- FWCI
- 19.18
- Type
- journal article
- Language
- en
- Open access
- green
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- The paper
- Ruiz Espelt, L., McPherson, I. S., Wiensch, E. M., & Yoon, T. P. (2015). Enantioselective Conjugate Additions of α-Amino Radicals via Cooperative Photoredox and Lewis Acid Catalysis. Journal of the American Chemical Society. https://doi.org/10.1021/ja512746q
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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