Light-Induced Protein Degradation with Photocaged PROTACs

Xue, Gang, Wang, Kun, Zhou, Danli, Zhong, Hanbing, Pan, Zhengying·2019·Journal of the American Chemical Society
DOI 10.1021/jacs.9b06422

Cited by (383)

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  67. BindingDB Entry 50022943: Synthesis, SAR, and application of JQ1 analogs as PROTACs for cancer therapy.
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  73. BindingDB Entry 50012249: Designing an eEF2K-Targeting PROTAC small molecule that induces apoptosis in MDA-MB-231 cells.
    BindingDB · 2022 · UC San Diego
  74. BindingDB Entry 50021317: Progress in the controllability technology of PROTAC.
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  75. BindingDB Entry 50016429: Emerging targeted protein degradation tools for innovative drug discovery: From classical PROTACs to the novel and beyond.
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  76. BindingDB Entry 50023478: PROTAC unleashed: Unveiling the synthetic approaches and potential therapeutic applications.
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  77. BindingDB Entry 50017547: Discovery of BP3 as an efficacious proteolysis targeting chimera (PROTAC) degrader of HSP90 for treating breast cancer.
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  78. BindingDB Entry 50018350: Recent advances in epigenetic proteolysis targeting chimeras (Epi-PROTACs).
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  79. BindingDB Entry 50023360: PROTAC technology: From drug development to probe technology for target deconvolution.
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  80. BindingDB Entry 50013395: Discovery of novel anti-angiogenesis agents. Part 11: Development of PROTACs based on active molecules with potency of promoting vascular normalization.
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  81. BindingDB Entry 50020203: Exploitation of Proximity-Mediated Effects in Drug Discovery: An Update of Recent Research Highlights in Perturbing Pathogenic Proteins and Correlated Issues.
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