Lumpidin, a Novel Biomarker of Some Ochratoxin A Producing Penicillia
Abstract
The novel compound lumpidin (1) has been isolated as a major compound from an isolate of Penicillium nordicum. Compound 1 is a diketopiperazine with a unique ring system likely to be a condensate of one mole each of L-tryptophan, L-phenylalanine, and L-homo-proline. The fact that 1 has been detected from only three out of sixteen isolates of P. nordicum indicates that lumpidin-producing isolates might represent a separate and third ochratoxin A producing Penicillium species.
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Penicillium chrysogenum produces secalonic acid D and F and/or a metabolite related to lumpidin.
“P. chrysogenum produces secalonic acid D and F and/or a metabolite related to lumpidin”
From Fleming’s penicillin producing strain is not Penicillium chrysogenum but P. rubens (2011) · cites this paper as Larsen et al. 2001
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Fleming’s penicillin producing strain is not Penicillium chrysogenum but P. rubens
Houbraken, J., Frisvad, J. C., & Samson, R. A. (2011) · IMA Fungus · doi:10.5598/imafungus.2011.02.01.12 · Cited by 262 · see citing works
- Authors
- Larsen, T. O., Petersen, B. O., & Duus, J. Ø.
- Affiliations
- Carlsberg Laboratory (DK)
- Corresponding author
- Larsen, Thomas Ostenfeld
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2001-09-14
- Volume
- 49
- Issue
- 10
- Pages
- 5081-5084
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W2003674851
- Cited by
- 14
- References
- 0
- Citations by year
- 2017: 1 · 2016: 3 · 2015: 1 · 2013: 1 · 2012: 1
- FWCI
- 1.82
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Agricultural and Food Chemistry (publishedVersion)
- PubMed (publishedVersion)
- Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU) (submittedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Mycotoxins in Agriculture and Food
- Health Sciences › Medicine › Pharmacology › Microbial Natural Products and Biosynthesis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Microbial Metabolism and Applications
- Keywords
- ochratoxin A, Penicillium nordicum, diketopiperazines, fungal secondary metabolites, biomarkers, tryptophan, phenylalanine, fungal taxonomy, mycotoxigenic fungi
- MeSH terms
- Imidazoles, Magnetic Resonance Spectroscopy, Ochratoxins, Penicillium, Piperazines, Molecular Structure, Biomarkers
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