Antioxidant, Antibacterial, and Antibiofilm Properties of Polyphenols from Muscadine Grape (Vitis rotundifolia Michx.) Pomace against Selected Foodborne Pathogens
Abstract
Polyphenols are predominantly secondary metabolites in muscadine grapes, playing an important role in the species' strong resistance to pests and diseases. This study examined the above property by evaluating the antioxidant, antibacterial, and antibiofilm activities of muscadine polyphenols against selected foodborne pathogens. Results showed that antioxidant activity for different polyphenols varied greatly, ranging from 5 to 11.1 mmol Trolox/g. Antioxidant and antibacterial activities for polyphenols showed a positive correlation. Muscadine polyphenols exhibited a broad spectrum of antibacterial activity against tested foodborne pathogens, especially Staphylococcus aureus (MIC = 67-152 mg/L). Muscadine polyphenols at 4 × MIC caused nearly a 5 log10 CFU/mL drop in cell viability for S. aureus in 6 h with lysis, whereas at 0.5 × MIC they inhibited its biofilm formation and at 16 × MIC they eradicated biofilms. Muscadine polyphenols showed synergy with antibiotics and maximally caused a 6.2 log10 CFU/mL drop in cell viability at subinhibitory concentration.
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Muscadine grape polyphenols exhibit strong antibacterial activities against a broad range of food-borne pathogens, mainly Staphylococcus aureus.
“Muscadine grape polyphenols exhibited strong antibacterial activities against a broad range of food-borne pathogens, mainly Staphylococcus aureus.”
From Valorization of Fruit Waste for Bioactive Compounds and Their Applications in the Food Industry (2023) · cites this paper as [152]
A decrease of nearly 5 log10 CFU/mL in S. aureus cell viability was observed over 6 h with lysis.
“A reported decrease of nearly 5 log10 CFU/mL in cell viability for S. aureus was observed in a 6 h period with lysis [152].”
From Valorization of Fruit Waste for Bioactive Compounds and Their Applications in the Food Industry (2023) · cites this paper as [152]
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The high-value and sustainable utilization of grape pomace: A review
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- Authors
- Xu, C., Yagiz, Y., Hsu, W.-Y., Simonne, A., Lu, J., & Marshall, M. R.
- Affiliations
- University of Florida (US)
- China Agricultural University (CN)
- Corresponding author
- Marshall, Maurice R.
- Venue
- Journal of Agricultural and Food Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2014-07-03
- Volume
- 62
- Issue
- 28
- Pages
- 6640-6649
- ISSN
- 0021-8561 (ISSN-L)
- 1520-5118
- OpenAlex
- W2002303667
- Cited by
- 118
- References
- 0
- Citations by year
- 2026: 3 · 2025: 11 · 2024: 9 · 2023: 14 · 2022: 11 · 2021: 9 · 2020: 11 · 2019: 9 · 2018: 15 · 2017: 10 · 2016: 9 · 2015: 7
- FWCI
- 6.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Agricultural and Food Chemistry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Physical Sciences › Chemistry › Organic Chemistry › Antimicrobial agents and applications
- Keywords
- muscadine grape, Vitis rotundifolia, grape pomace, polyphenols, antioxidant activity, antibacterial activity, antibiofilm activity, Staphylococcus aureus, foodborne pathogens, biofilm eradication, antibiotic synergy, subinhibitory concentrations
- MeSH terms
- Anti-Bacterial Agents, Antioxidants, Drug Synergism, Foodborne Diseases, Fruit, Staphylococcus aureus, Biofilms, Vitis, Polyphenols
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