Potential oxidative pathways of brain catecholamines

Tse, Daniel C. S., McCreery, Richard L., Adams, Ralph N.·1976·Journal of Medicinal Chemistry
DOI 10.1021/jm00223a008

Cited by (416)

Items 201–300 of 416

  1. l-DOPA-induced 6-hydroxydopamine production in the striata of rodents is sensitive to the degree of denervation
    Anupom Borah, Kochupurackal P. Mohanakumar · 2009 · Neurochemistry International
  2. Myoglobin Modification by Enzyme‐Generated Dopamine Reactive Species
    Stefania Nicolis, Matteo Zucchelli, Enrico Monzani, Luigi Casella · 2008 · Chemistry - A European Journal
  3. Correlating Selective Electrocatalysis of Dopamine and Ascorbic Acid Electrooxidation at Nanoporous Gold Surfaces with Structural-Defects
    Abhishek Kumar, Josué M. Gonçalves, Jéssica Soares da Silva · 2019 · Journal of The Electrochemical Society
  4. Selective electrochemical detection of dopamine in a microfluidic channel on carbon nanoparticulate electrodes
    Ewa Roźniecka, Martin Jönsson‐Niedziółka, Anna Celebańska · 2014 · The Analyst
  5. The epinephrine assay for superoxide: Why dopamine does not work
    Ramia Alhasan, David Njus · 2008 · Analytical Biochemistry
  6. Cytoprotective role of taurine in a renal epithelial cell culture model
    Bärbel Eppler, Ralph Dawson · 2002 · Biochemical Pharmacology
  7. Mass spectrometric observation on free radicals during electrooxidation of dopamine
    Jie Jiang, Yuchen Cao, Jilin Liu, Hong Zhang, Guangfeng Kan, Kai Yu · 2021 · Analytica Chimica Acta
  8. Neuromelanin in the Human Brain: A Review and Atlas of Pigmented Cells in the Substantia Nigra
    Kamen G. Usunoff, Dimitar E. Itzev, Wladimir A. Ovtscharoff, E. Marani · 2002 · Archives of Physiology and Biochemistry
  9. Copper increases the ability of 6‐hydroxydopamine to generate oxidative stress and the ability of ascorbate and glutathione to potentiate this effect: potential implications in Parkinson's disease
    Antón Cruces‐Sande, Estefanía Méndez‐Álvarez, Ramón Soto‐Otero · 2017 · Journal of Neurochemistry
  10. MPTP
    Joyce E. Royland, J. William Langston · 1998 · Humana Press eBooks
  11. Introduction to In Vivo Voltammetry
    Joseph B. Justice · 1987 · Humana Press eBooks
  12. 3,4-Dihydroxybenzylamine: An Improved Dopamine Analog Cytotoxic for Melanoma Cells in Part Through Oxidation Products Inhibitory to DNA Polymerase
    George B. FitzGerald, Michael M. Wick · 1983 · Journal of Investigative Dermatology
  13. Scutellarin activates IDH1 to exert antitumor effects in hepatocellular carcinoma progression
    Zhao Cui, Caifeng Li, Wei Liu, Mo Sun, Shiwen Deng, Junxian Cao, Hongjun Yang, Peng Chen · 2024 · Cell Death and Disease
  14. Microscale reactor embedded with Graphene/hierarchical gold nanostructures for electrochemical sensing: application to the determination of dopamine
    Mahsa Jalali, Elizabeth Filine, Samantha R. Dalfen · 2020 · Microchimica Acta
  15. Role of Protein Damage Inflicted by Dopamine Metabolites in Parkinson’s Disease: Evidence, Tools, and Outlook
    Alexander K. Hurben, Natalia Y. Tretyakova · 2022 · Chemical Research in Toxicology
  16. Structural characterization by infrared multiple photon dissociation spectroscopy of protonated gas-phase ions obtained by electrospray ionization of cysteine and dopamine
    Jeffrey D. Steill, Jan Szczepański, Jos Oomens · 2011 · Analytical and Bioanalytical Chemistry
  17. Neuroglobin Modification by Reactive Quinone Species
    Stefania Nicolis, Enrico Monzani, Alessandro Pezzella, Paolo Ascenzi, Diego Sbardella, Luigi Casella · 2013 · Chemical Research in Toxicology
  18. Nonsteroidal anti-inflammatory drugs in Parkinson’s disease: possible involvement of quinone formation
    M. Asanuma, Ikuko Miyazaki · 2006 · Expert Review of Neurotherapeutics
  19. Algorithm for converting peak detection and tailing into chromatographic information
    W. A. Spencer, Lockhart Burgess. Rogers · 1980 · Analytical Chemistry
  20. In vivo protein targets for increased quinoprotein adduct formation in aged substantia nigra
    Guohua Yu, Huiyan Liu, Wei Ping Zhou, Xuewei Zhu, Chao Yuan Yu, Na Wang, Yi Zhang, Ji Ma, Yulan Zhao, Yuanyuan Xu et al. · 2015 · Experimental Neurology
  21. Catecholamine Analogs as Potential Antitumor Agents
    John S. Driscoll · 1979 · Journal of Pharmaceutical Sciences
  22. Effects of acute and chronic systemic administration of some typical antipsychotic drugs on turnover of dopamine and potassium ion-induced release of dopamine in the striatum of the rat in vivo
    Terrell Ann Patterson, James O. Schenk · 1991 · Neuropharmacology
  23. Oxidative metabolism of dopamine: A colour reaction from human midbrain analysed by mass spectrometry
    Angela De Iuliis, Giorgio Arrigoni, Liselotte Andersson, Pamela Zambenedetti, Alessandro P. Burlina, Peter James, Paola Arslan, Fábio Vianello · 2008 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  24. Electrochemically Degraded Dopamine Film for the Determination of Dopamine
    Hye-Young Chang, Dong Il Kim, Yu Chul Park · 2006 · Electroanalysis
  25. Molecular mechanism of biological action of the serotonergic neurotoxin 5,7-dihydroxytryptamine
    Achintya K. Sinhababu, Ronald T. Borchardt · 1988 · Neurochemistry International
  26. Salicylic acid protects against chronic l-DOPA-induced 6-OHDA generation in experimental model of parkinsonism
    Anupom Borah, Kochupurackal P. Mohanakumar · 2010 · Brain Research
  27. Highly Uniform, Flexible Microelectrodes Based on the Clean Single-Walled Carbon Nanotube Thin Film with High Electrochemical Activity
    Nguyễn Xuân Viết, Shigeru Kishimoto, Yutaka Ohno · 2019 · ACS Applied Materials & Interfaces
  28. Activation of the microsomal glutathione S-transferase by metabolites of α-methyldopa
    Guido R.M.M. Haenen, Frank P. Jansen, Nico Vermeulen · 1991 · Archives of Biochemistry and Biophysics
  29. Binding of serotonin and dopamine to ‘serotonin binding proteins’ in bovine frontal cortex: evidence for iron-induced oxidative mechanisms
    Marlene Jiménez-Del-Río, Carlos Velez‐Pardo, Jef A. PINXTEREN · 1993 · European Journal of Pharmacology Molecular Pharmacology
  30. Proteome-Wide Profiling of Cellular Targets Modified by Dopamine Metabolites Using a Bio-Orthogonally Functionalized Catecholamine
    Alexander K. Hurben, Luke N. Erber, Natalia Y. Tretyakova, Todd M. Doran · 2021 · ACS Chemical Biology
  31. Hydroxybenzaldoximes Are D ‐GAP‐Competitive Inhibitors of E. coli 1‐Deoxy‐ D ‐Xylulose‐5‐Phosphate Synthase
    David Bartee, Francine Morris, Amer Al‐khouja · 2015 · ChemBioChem
  32. Ascorbate in the treatment of experimental transplanted melanoma
    GG Meadows, Herbert F. Pierson, RM Abdallah · 1991 · American Journal of Clinical Nutrition
  33. Pyrolysis-gas chromatography-mass spectrometry of synthetic neuromelanins
    Anna Dzierżęga‐Lęcznar, Ewa Chodurek, Krystyna B. Stȩpień, Tadeusz Wilczok · 2002 · Journal of Analytical and Applied Pyrolysis
  34. Determination of sulfur dioxide by reaction with electrogenerated bromine in a thin-layer cell having a gas-porous wall
    Stanley Bruckenstein, Kevin A. Tucker, Paul R. Gifford · 1980 · Analytical Chemistry
  35. Iron- and peroxide-dependent conjugation of dopamine with cysteine: oxidative routes to the novel brain metabolite 5-S-cysteinyldopamine
    Anna Palumbo, Marco d’Ischia, Giovanna Misuraca, Luigi De Martino, Giuseppe Prota · 1995 · Biochimica et Biophysica Acta (BBA) - General Subjects
  36. Prostaglandin H Synthase-1-Catalyzed Bioactivation of Neurotransmitters, Their Precursors, and Metabolites: Oxidative DNA Damage and Electron Spin Resonance Spectroscopy Studies
    Luísa M. L. Gonçalves, Annmarie Ramkissoon, Peter G. Wells · 2009 · Chemical Research in Toxicology
  37. The relationship between oxidative stress and post-translational modification of the dopamine transporter in bipolar disorder
    Helena Kyunghee Kim, Ana C. Andreazza · 2012 · Expert Review of Neurotherapeutics
  38. Effect of liposome membranes on disaggregation of amyloid β fibrils by dopamine
    Huong Thi Vu, Toshinori Shimanouchi, Daisuke Ishikawa, Tadaharu Matsumoto, Hisashi Yagi, Yuji Goto, Hiroshi Umakoshi, Ryoichi Kuboi · 2012 · Biochemical Engineering Journal
  39. Model neuromelanins as antioxidative agents during lipid peroxidation
    Tadeusz Wilczok, Krystyna B. Stȩpień, Anna Dzierżęga‐Lęcznar, Alicja Zajdel, Adam Wilczok · 1999 · Neurotoxicity Research
  40. Improved electrochemical properties of stearate-graphite paste electrodes after albumin and phospholipid treatments
    Charles D. Blaha, Douglas Liu, Anthony G. Phillips · 1996 · Biosensors and Bioelectronics
  41. Extracellular dopamine in the rat striatum during ischemia and reperfusion as measured by in vivo electrochemistry and in vivo microdialysis
    Emma R. Wood, Ariane Coury, Charles D. Blaha · 1992 · Brain Research
  42. Dopamine-Modified Chitosan Patterning Hydrogel with Dynamic Information Storage Ability
    Yuting Li, Chen Yang, Feng Hu · 2024 · ACS Applied Materials & Interfaces
  43. Methylene blue intercalated aptamer to amplify signals toward sensitively electrochemical detection of dopamine released from living Parkinson's disease model cells
    Chuyue Tang, Zhuo Zou, Taotao Liang, Chengsong Yuan, Jiechang Gao, Kanglai Tang, Chang Ming Li · 2022 · Sensors and Actuators Reports
  44. Free-standing Plastic electrodes: Formulation, electrochemical characterization and application to dopamine detection
    Massimiliano Marsilia, Sabina Susmel · 2017 · Sensors and Actuators B Chemical
  45. Molecularly imprinted silica films prepared by electroassisted deposition for the selective detection of dopamine
    María Porcel-Valenzuela, Alfonso Salinas‐Castillo, Emilia Morallón · 2015 · Sensors and Actuators B Chemical
  46. A novel hydrogen peroxide-dependent oxidation pathway of dopamine via 6-hydroxydopamine
    Paola Manini, Lucia Panzella, Alessandra Napolitano · 2003 · Tetrahedron
  47. Role of azide concentration in pulse radiolysis studies of oxidation: 3,4-dihydroxyphenylalanine
    Chris Lambert, Terence George Truscott, E. J. Land, Patrick Anthony Riley · 1991 · Journal of the Chemical Society Faraday Transactions
  48. Iron and copper ions accelerate and modify dopamine oxidation to eumelanin: implications for neuromelanin genesis
    Shosuke Ito, Alessandra Napolitano, Tadeusz Sarna, Kazumasa Wakamatsu · 2022 · Journal of Neural Transmission
  49. Taurine Inhibition of Iron-Stimulated Catecholamine Oxidation
    Ralph Dawson, Elisa Tang, Debbie Shih · 1998 · Advances in experimental medicine and biology
  50. Anodic fracturing and vacuum heat treated annealing of pitch-based carbon fibers
    Greg M. Swain, Theodore Kuwana · 1992 · Analytical Chemistry
  51. Interaction Between the Angiotensin-(1–7) Mas Receptor and the Dopamine D2 Receptor
    Natalia L. Rukavina Mikusic, Mauro G. Silva, Luciana R. Mazzitelli, Robson A.S. Santos, Karina A. Gómez, Hernán E. Grecco, Mariela Mercedes Gironacci · 2021 · Hypertension
  52. Facile synthesis of Au-graphene nanocomposite for the selective determination of dopamine
    Minjeong Kwak, Sohee Lee, Dong‐Won Kim, Seung‐Keun Park, Yuanzhe Piao · 2016 · Journal of Electroanalytical Chemistry
  53. Understanding the role of glycogen synthase kinase-3 in L-DOPA-induced dyskinesia in Parkinson’s disease
    Hojin Choi, Seong‐Ho Koh · 2017 · Expert Opinion on Drug Metabolism & Toxicology
  54. Cyclization step of noradrenaline and adrenaline autoxidation: a quantum chemical study
    Nejc Umek · 2020 · RSC Advances
  55. The chemical interaction between the neurotransmitter dopamine and the antipsychotic drugs olanzapine and quetiapine
    Raphael Prata Bacil, Estenio A. de O. Marcondes Filho, Kevin de Aquino Dias, Marcelo Cecconi Portes, William Reis de Araujo, Diogo Oliveira‐Silva, Alcindo A. Dos Santos, Sı́lvia H.P. Serrano · 2021 · Journal of Electroanalytical Chemistry
  56. Manganese and copper promote the binding of dopamine to “serotonin binding proteins” in bovine frontal cortex
    Carlos Velez‐Pardo · 1995 · Neurochemistry International
  57. Dopamine Agonist Pergolide Prevents Levodopa-Induced Quinoprotein Formation in Parkinsonian Striatum and Shows Quenching Effects on Dopamine-Semiquinone Generated in Vitro
    Ikuko Miyazaki, Masato Asanuma, Francisco J. Javier Diaz-Corrales, Ko Miyoshi, Norio Ogawa · 2005 · Clinical Neuropharmacology
  58. Studies of interaction between iron (III) and intermediates of synthetic neuromelanin by means of cyclic voltammetry of and dopamine
    Jianguo Wang, Yuling Wang, Hui Lv, Fei Hui, Yong Ma, Shijian Lu, Qiuju Sha, Erkang Wang · 2006 · Journal of Electroanalytical Chemistry
  59. Taurine inhibition of metal-stimulated catecholamine oxidation
    Ralph Dawson, Deron Baker, Baerbel Eppler · 2000 · Neurotoxicity Research
  60. Intracerebral infusion of 3H‐dopamine and 3H‐mannitol in the striatum of halothane‐anaesthetized male rats.A dual‐probe microdialysis study of long‐distance diffusion
    Malin Höistad, Ján Kehr, Beth Andbjer · 2000 · European Journal of Neuroscience
  61. Oxygen-dependent free radicals in spermine oxidation cytostasis and chemiluminescence and the role of superoxide dismutase
    J. M. Gaugas, David L. Dewey · 1980 · British Journal of Cancer
  62. Modulation of Reactive Oxygen Species Homeostasis as a Pleiotropic Effect of Commonly Used Drugs
    Carolin Thomas, Lia Wurzer, Ernst Malle, Michael Ristow, Corina T. Madreiter‐Sokolowski · 2022 · Frontiers in Aging
  63. Neurotoxins as Preclinical Models for Parkinson’s Disease
    Juan Segura‐Aguilar · 2018 · Neurotoxicity Research
  64. Density Functional Theory-Based Calculation Shed New Light on the Bizarre Addition of Cysteine Thiol to Dopaquinone
    Ryo Kishida, Shosuke Ito, Manickam Sugumaran, Ryan Lacdao Arevalo, Hiroshi Nakanishi, Hideaki Kasai · 2021 · International Journal of Molecular Sciences
  65. Electrochemical determination of selected neurotransmitters at electrodes modified with oppositely charged carbon nanoparticles
    Magdalena Kundys, Katarzyna Szot, Ewa Roźniecka · 2014 · Analytical Methods
  66. Fish and Clips: A Convenient Strategy to Identify Tyrosinase Substrates with Rapid Activation Behavior for Materials Science Applications
    Justus Horsch, Patrick Wilke, Heike Stephanowitz · 2019 · ACS Macro Letters
  67. Molecular cloning, localization and characterization of a 40‐kDa catecholamine‐regulated protein
    Venugopalan D. Nair, Ram K. Mishra · 2001 · Journal of Neurochemistry
  68. Preparation, Characterization and Analytical Applications of a New and Novel Electrically Conducting Polymer
    Fabiana D’Eramo, Leonides Sereno, Alejandro Heraldo Arévalo · 2006 · Electroanalysis
  69. Autoxidation of catechol(amine)s
    M. T. I. W. Schüsler-Van Hees, G. M. J. Beijersbergen Van Henegouwen, P. Stoutenberg · 1985 · Pharmacy World & Science
  70. Melanin as a virulence factor of Paracoccidioides brasiliensis and other dimorphic pathogenic fungi
    Carlos P. Taborda, Lineu Prestes, Marcelo Barreto da Silva · 2009
  71. FTO – an Electrode Material for the Stable Electrochemical Determination of Dopamine
    Gero Göbel, Anja Talke, Fred Lisdat · 2017 · Electroanalysis
  72. Cyclooxygenase activity contributes to the monoaminergic damage caused by serial exposure to stress and methamphetamine
    Nicole A. Northrop, Bryan K. Yamamoto · 2013 · Neuropharmacology
  73. Micronutrients and Risk of Parkinson’s Disease
    Ayesha Z. Sherzai, Michele Tagliati, Katherine Park, Shant Pezeshkian, Dean Sherzai · 2016 · Gerontology and Geriatric Medicine
  74. Nanogap-Based Electrochemical Measurements at Double-Carbon-Fiber Ultramicroelectrodes
    Pavithra Pathirathna, Ryan J. Balla, Shigeru Amemiya · 2018 · Analytical Chemistry
  75. Overexpression of Vesicular Monoamine Transporter-2 may Block Neurotoxic Metabolites from Cytosolic Dopamine: a Potential Neuroprotective Therapy for Parkinson's Disease.
    Segura-Aguilar, David L. Sulzer, Fabio Andrea Zucca, Luigi Zecca · 2019 · PubMed
  76. Polymerizing Like Mussels Do: Toward Synthetic Mussel Foot Proteins and Resistant Glues
    Justus Horsch, Patrick Wilke, Matthias Pretzler · 2018 · Angewandte Chemie
  77. 2‐Mercaptonicotinoyl glycine, a new potent melanogenesis inhibitor, exhibits a unique mode of action while preserving melanocyte integrity
    Peggy Sextius, Emilie Warrick, Amélie Prévot‐Guéguiniat, Guillaume Léreaux, Florence Boirre, Ludwig Baux, Safa Ben Hassine, Jie Qiu, Xiaoming Huang, Jinzhu Xu et al. · 2024 · Pigment Cell & Melanoma Research
  78. Electrochemical Detection of Dopamine with Graphene Oxide Carbon Dots Modified Electrodes
    Omar Isaac Torres-Soto, Alejandro Vega‐Ríos, Rocio Berenice Dominguez · 2025 · Chemosensors
  79. Facile Fabrication of Mussel‐Inspired Multifunctional Polymeric Membranes with Remarkable Anticoagulant, Antifouling, and Antibacterial Properties
    M. Shao, Rui Wang, Wei-Feng Zhao, Jian-Shu Li, Chang-Sheng Zhao · 2018 · Macromolecular Materials and Engineering
  80. Determination of the Second-Order Rate Constant for the Reduction of Dopamine Quinone with Ascorbic Acid
    David Sopchak, Barry Miller · 2000 · The Journal of Physical Chemistry A
  81. Circulating antibodies to cysteinyl catecholamines in amyotrophic lateral sclerosis and Parkinson's disease patients
    L. Salauze, C. van der Velden, I. Lagroye · 2005 · Amyotrophic Lateral Sclerosis
  82. Neurotoxic Phenylalkylamines and Indolealkylamines
    H. G. Baumgarten, Bernd Alois Zimmermann · 1994 · Springer eBooks
  83. More Accurate Measurement of Return Peak Current in Cyclic Voltammetry Using Diffusional Baseline Fitting
    David S. Macedo, Theo Rodopoulos, Mikko Vepsäläinen · 2024 · Analytical Chemistry
  84. Fabrication and Optimization of a Molecularly Imprinted Carbon Fiber Microelectrode for Selective Detection of Met-enkephalin Using Fast-Scan Cyclic Voltammetry
    Nicole A. Villarini, Nathan Robins, Yangguang Ou · 2024 · ACS Applied Materials & Interfaces
  85. Phytochemical synergies in BK002: advanced molecular docking insights for targeted prostate cancer therapy
    Moon Nyeo Park, Jinwon Choi, Md. Maharub Hossain Fahim, Estéfani Alves Asevedo, Fahrul Nurkolis, Rosy Iara Maciel de Azambuja Ribeiro, Han Na Kang, Sojin Kang, Rony Abdi Syahputra, Bonglee Kim · 2025 · Frontiers in Pharmacology
  86. Reaction of malondialdehyde with amine neurotransmitters. Formation and oxidation chemistry of fluorescent 1,4-dihydropyridine adducts
    Marco d’Ischia, Alessandra Napolitano, Claudio Costantini · 1995 · Tetrahedron
  87. Immunohistochemical evidence and ultrastructural compartmentalization of a new antioxidant enzyme in the rat substantia nigra
    Francesco Fornai, Marco Gesi, Michela Saviozzi, Paola Lenzi, Simona Piaggi, Michela Ferrucci, Alessandro Casini · 2001 · Journal of Neurocytology
  88. Serotonin binding proteins “SBP”: Target proteins and tool for in vitro neurotoxicity studies
    Marlene Jiménez-Del-Río, Carlos Velez‐Pardo, Guy Ebinger, Georges Vauquelin · 1995 · General Pharmacology The Vascular System
  89. Peroxynitrite mediated linoleic acid oxidation and tyrosine nitration in the presence of synthetic neuromelanins.
    Karolina Stępień, Adam Wilczok, Alicja Zajdel, Anna Dzierżęga‐Lęcznar, Tadeusz Wilczok · 2000 · Acta Biochimica Polonica
  90. Photo-oxidation and Photoreduction of Catechols by Chlorophyll Metabolites and Methylene Blue
    Lisa M. Landino, Zachary T. Shuckrow, Alexander S. Mooney · 2022 · Chemical Research in Toxicology
  91. Versatile Electrochemical Platform for the Determination of Phenol‐like Compounds Based on Laccases from Different Origins
    Ignacio Borón, Sonia Alejandra Wirth, Fernando Battaglini · 2016 · Electroanalysis
  92. Complicated function of dopamine in Aβ-related neurotoxicity: Dual interactions with Tyr10 and SNK(26–28) of Aβ
    Mengmeng Liu, Lu Kou, Yannan Bin, Liping Wan, Juan Xiang · 2016 · Journal of Inorganic Biochemistry
  93. The time‐dependent inactivation of human brain dihydropteridine reductase by the oxidation products of L‐dopa
    Paul Waring · 1986 · European Journal of Biochemistry
  94. A kinetic analysis of a catechol-specific binding site in the microsomal fraction from the rabbit aorta
    Robert R. Ruffolo Jr., Richard L. McCreery, Popat N. Patil · 1976 · European Journal of Pharmacology
  95. 522—Catalytic oxydation of biological components on platinum electrodes modified by adsorbed metals
    Mizuho Sakamoto, Kiyoko Takamura · 1982 · Journal of Electroanalytical Chemistry
  96. Do mtDNA Mutations Participate in the Pathogenesis of Sporadic Parkinsons Disease?
    Elmar Kirches · 2009 · Current Genomics
  97. Production of cysteinyl-dopamine during intravenous dopamine therapy
    Julia L. Magnay, Jeff Tong, Rosa Drangova · 2001 · Kidney International
  98. Covalent binding of catechols to src family SH2 domains
    Christopher T. Jagoe, Scott E. Kreifels, Jongming Li · 1997 · Bioorganic & Medicinal Chemistry Letters
  99. Cyclooxygenase-Independent Neuroprotective Effects of Aspirin Against Dopamine Quinone-Induced Neurotoxicity
    Masato Asanuma, Ikuko Miyazaki, Yuri Kikkawa · 2012 · Neurochemical Research
  100. Manganese-stimulated redox cycling of dopamine derivatives: Implications for manganism
    Praneet Kaur Marwah, Gijong Paik, Christopher J. Issa · 2022 · NeuroToxicology