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The Discovery of Ezetimibe: A View from Outside the Receptor
Abstract
The term “rationale drug design ” has been used for more than 30 years to describe a marriage of experiment and technology intended to promote a more directed approach toward drug discovery, often focusing on
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Ezetimibe was initially discovered as an inhibitor of ACAT2.
“EZ was initially discovered as an inhibitor of ACAT2 (11).”
From Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake (2023) · cites this paper as [11]
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Cited by
Sorted by citations
Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake
Ferrari, A., Whang, E., Xiao, X., Kennelly, J. P., Romartinez-Alonso, B., Mack, J. J., Weston, T., Chen, K., Kim, Y., Tol, M. J., et al. (2023) · Science · doi:10.1126/science.adf0966 · Cited by 61
Metadata
- Authors
- Clader, J. W.
- Affiliations
- Cardiovascular and CNS Medicinal Chemistry Department, Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033-0539
- Venue
- Journal of Medicinal Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2003-12-09
- Volume
- 47
- Issue
- 1
- Pages
- 1-9
- ISSN
- 0022-2623
- 1520-4804
- Cited by
- 325
- References
- 0
- Language
- en
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