The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
What Do Medicinal Chemists Actually Make? A 50-Year Retrospective
Abstract
ADVERTISEMENT RETURN TO ISSUEPerspectiveNEXTWhat Do Medicinal Chemists Actually Make? A 50-Year RetrospectiveW. Patrick Walters*, Jeremy Green, Jonathan R. Weiss, and Mark A. MurckoView Author Information Vertex Pharmaceuticals Inc., 130 Waverly Street, Cambridge, Massachusetts 02139, United StatesVoice: 617-444-6242. Fax: 617-444-6688. E-mail: [email protected]Cite this: J. Med. Chem. 2011, 54, 19, 6405–6416Publication Date (Web):July 14, 2011Publication History Received25 April 2011Published online31 August 2011Published inissue 13 October 2011https://pubs.acs.org/doi/10.1021/jm200504phttps://doi.org/10.1021/jm200504preview-articleACS PublicationsCopyright © 2011 American Chemical SocietyRequest reuse permissionsArticle Views18194Altmetric-Citations314LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Drug discovery,Medicinal chemistry,Molecules,Partition coefficient,Pharmaceuticals Get e-Alerts
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Citations
Cites
Molecular properties that influence the oral bioavailability of drug candidates
Veber, D. F., Johnson, S. R., Cheng, H.-Y., Smith, B. R., Ward, K. W., & Kopple, K. D. (2002) · Journal of Medicinal Chemistry · doi:10.1021/jm020017n · Cited by 8,420
A quantitative analysis of kinase inhibitor selectivity
Karaman, M. W., Herrgard, S., Treiber, D. K., Gallant, P., Atteridge, C. E., Campbell, B. T., Chan, K. W., Ciceri, P., Davis, M. I., Edeen, P. T., et al. (2008) · Nature Biotechnology · doi:10.1038/nbt1358 · Cited by 2,466
The influence of drug-like concepts on decision-making in medicinal chemistry
Leeson, P. D., & Springthorpe, B. (2007) · Nature Reviews Drug Discovery · doi:10.1038/nrd2445 · Cited by 2,403
Kansy, M., Senner, F., & Gubernator, K. (1998) · Journal of Medicinal Chemistry · doi:10.1021/jm970530e · Cited by 1,304
Can we rationally design promiscuous drugs?
HOPKINS, A., MASON, J., & OVERINGTON, J. (2006) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2006.01.013 · Cited by 469
Ligand efficiency and fragment-based drug discovery
Bembenek, S. D., Tounge, B. A., & Reynolds, C. H. (2009) · Drug Discovery Today · doi:10.1016/j.drudis.2008.11.007 · Cited by 196
Cited by
Escape from Flatland 2: complexity and promiscuity
Lovering, F. (2013) · MedChemComm · doi:10.1039/c2md20347b · Cited by 1,444
The role of ligand efficiency metrics in drug discovery
Hopkins, A. L., Keserü, G. M., Leeson, P. D., Rees, D. C., & Reynolds, C. H. (2014) · Nature Reviews Drug Discovery · doi:10.1038/nrd4163 · Cited by 1,181
The influence of lipophilicity in drug discovery and design
Arnott, J. A., & Planey, S. L. (2012) · Expert Opinion on Drug Discovery · doi:10.1517/17460441.2012.714363 · Cited by 868
The UDP-glucuronosyltransferases: Their role in drug metabolism and detoxification
Rowland, A., Miners, J. O., & Mackenzie, P. I. (2013) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2013.02.019 · Cited by 709
Metallaphotoredox-enabled deoxygenative arylation of alcohols
Dong, Z., & MacMillan, D. W. C. (2021) · Nature · doi:10.1038/s41586-021-03920-6 · Cited by 432
Metadata
- Authors
- Walters, W. P., Green, J., Weiss, J. R., & Murcko, M. A.
- Venue
- Journal of Medicinal Chemistry
- Publisher
- American Chemical Society (ACS)
- Published
- 2011-08-31
- Volume
- 54
- Issue
- 19
- Pages
- 6405-6416
- ISSN
- 0022-2623 (ISSN-L)
- 1520-4804
- OpenAlex
- W1966316733
- Cited by
- 387
- References
- 6
- FWCI
- 22.98
- Type
- journal article
- Language
- en
- Open access
- closed
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- Walters, W. P., Green, J., Weiss, J. R., & Murcko, M. A. (2011). What Do Medicinal Chemists Actually Make? A 50-Year Retrospective. Journal of Medicinal Chemistry. https://doi.org/10.1021/jm200504p
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
